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Methyl 4-acetamido-2-ethoxybenzoate

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Identification
Molecular formula
C12H15NO4
CAS number
17852-52-7
IUPAC name
methyl 4-acetamido-2-ethoxy-benzoate
State
State

At room temperature, methyl 4-acetamido-2-ethoxybenzoate is typically in a solid state. It is stable under normal conditions but should be stored away from heat sources and direct sunlight to prevent decomposition.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.20
Boiling point (Celsius)
357.50
Boiling point (Kelvin)
630.70
General information
Molecular weight
251.27g/mol
Molar mass
251.2710g/mol
Density
1.1960g/cm3
Appearence

Methyl 4-acetamido-2-ethoxybenzoate typically appears as a white crystalline solid. It may also be found as a powder depending on the method of synthesis and processing. Like many aromatic compounds, it usually exhibits a distinct, pleasant odor.

Comment on solubility

Solubility of Methyl 4-Acetamido-2-ethoxy-benzoate (C12H15NO4)

Methyl 4-acetamido-2-ethoxy-benzoate is a compound that exhibits intriguing solubility characteristics. Generally, the solubility of this ester can be influenced by various factors, including polarity, molecular structure, and the presence of functional groups.

Factors Influencing Solubility

  • Polarity: The presence of both hydrophobic (the ethoxy and methyl groups) and hydrophilic (the acetamido group) regions in the molecule can affect its solubility. This dual nature allows the compound to dissolve in a range of solvents.
  • Solvent Compatibility: It is expected to be soluble in polar organic solvents such as methanol and ethanol, due to the availability of hydrogen bonding sites from the acetamido group.
  • Molecular Interactions: Interaction with solvents may vary significantly, with stronger solubility observed in solvents that can provide hydrogen bonds or dipole-dipole interactions.

In conclusion, methyl 4-acetamido-2-ethoxy-benzoate exhibits a moderate solubility profile, showcasing a versatile behavior in different solvent environments. Understanding its solubility can be crucial for applications in pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts About Methyl 4-Acetamido-2-Ethoxy-Benzoate

Methyl 4-acetamido-2-ethoxy-benzoate, often referred to in the chemical literature, is a compound that showcases a variety of interesting properties and applications:

  • Structural Insights: The presence of both an ethoxy group and an acetamido group in its structure contributes to its unique reactivity and solubility characteristics, making it a significant compound in organic chemistry.
  • Biological Relevance: This compound has garnered attention for its potential use in medicinal chemistry. Compounds with similar structures are often investigated for their anti-inflammatory and analgesic properties.
  • Synthesis Pathways: The synthesis of this compound often involves various organic reactions, including Esterification and Acetylation, illustrating fundamental concepts in organic synthesis.
  • Applications in Research: Methyl 4-acetamido-2-ethoxy-benzoate serves as an important intermediate in the synthesis of more complex molecules. Its derivatives may even lead to the discovery of new pharmaceuticals.
  • Chemical Behavior: The compound’s reactivity can be influenced by the substituents on the aromatic ring, leading to interesting studies in substitution reactions and mechanistic chemistry.

As with many compounds in organic chemistry, understanding methyl 4-acetamido-2-ethoxy-benzoate opens the door to a greater appreciation for the complexity and interconnectedness of chemical systems. Each component of the molecule plays a role in determining its properties, reactions, and ultimately, its applications in various scientific fields.

Synonyms
ETHOPABATE
Methyl 4-acetamido-2-ethoxybenzoate
59-06-3
Ethopabat
Benzoic acid, 4-(acetylamino)-2-ethoxy-, methyl ester
EINECS 200-414-3
MFCD00075809
UNII-F4X3L6068O
Methyl 4-(acetylamino)-2-ethoxybenzoate
DTXSID6046264
4-Acetamido-2-ethoxybenzoesaeuremethylester
F4X3L6068O
Ethopabate [USP:BAN]
DTXCID4026264
NCGC00160624-01
Ethopabate 100 microg/mL in Acetonitrile
Ethopabate (USP:BAN)
Ethyl Pabate
ETHOPABATE (MART.)
ETHOPABATE [MART.]
ETHOPABATE (USP-RS)
ETHOPABATE [USP-RS]
ETHOPABATE (USP MONOGRAPH)
ETHOPABATE [USP MONOGRAPH]
CAS-59-06-3
Amprol Plus (veterinary)
Methyl4-acetamido-2-ethoxybenzoate
Ethopabate (USP)
Methyl 2-ethoxy-4-acetamidobenzoate
Ethopabate (Standard)
Ethopabate - Technical
ETHOPABATE [MI]
4-acetylamino-2-ethoxybenzoic acid methyl ester
SCHEMBL540932
CHEMBL458769
ETHOPABATE [GREEN BOOK]
HY-B2138R
CHEBI:183844
HY-B2138
Tox21 111943
Tox21_111943
s3707
Methyl 4-acetamido-2-ethoxy-benzoate
AKOS015892662
Tox21_111943_1
CCG-213430
CS-8028
FE22866
NCGC00160624-02
NCGC00160624-03
NCGC00160624-04
AS-11898
SY226309
DB-053312
NS00000013
4-Acetamido-2-ethoxybenzoic acid, methyl ester
D08916
Ethopabate, VETRANAL(TM), analytical standard
AB01563313_01
4-Acetylamino-2-ethoxy-benzoic acid, methyl ester
SR-01000944203
Q5404419
SR-01000944203-1
BRD-K02475039-001-01-0
Ethopabate, British Pharmacopoeia (BP) Reference Standard
Ethopabate, United States Pharmacopeia (USP) Reference Standard
200-414-3
4-Acetylamino-2-ethoxy-benzoic acid methyl ester;4-acetamido-2-ethoxy-benzoic acid methyl ester;4-Acetamido-2-ethoxybenzoic acid met hyl ester