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Methyl 4-formylbenzoate

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Identification
Molecular formula
C9H8O3
CAS number
134-60-5
IUPAC name
methyl 4-formylbenzoate
State
State
Methyl 4-formylbenzoate is typically found in a solid state at room temperature.
Melting point (Celsius)
57.00
Melting point (Kelvin)
330.15
Boiling point (Celsius)
281.00
Boiling point (Kelvin)
554.15
General information
Molecular weight
164.16g/mol
Molar mass
164.1580g/mol
Density
1.1687g/cm3
Appearence

Methyl 4-formylbenzoate appears as a pale yellow crystalline powder or solid with a characteristic aromatic odor.

Comment on solubility

Solubility of Methyl 4-formylbenzoate

Methyl 4-formylbenzoate, with its unique structure, exhibits interesting solubility characteristics that are important for its applications in various chemical processes. Understanding the solubility of this compound can be crucial for both its practical use and theoretical considerations in chemistry.

Factors Affecting Solubility

Several factors influence the solubility of methyl 4-formylbenzoate in different solvents:

  • Polarity: This compound is moderately polar due to the presence of the formyl group (-CHO), which tends to enhance its solubility in polar solvents.
  • Hydrogen Bonding: The formyl group can engage in hydrogen bonding, improving solubility in alcohols and other hydrogen-bonding solvents.
  • Temperature: Generally, an increase in temperature can enhance solubility, making it more soluble in organic solvents when heated.

Solvent Compatibility

Methyl 4-formylbenzoate is expected to show varying degrees of solubility depending on the solvent used:

  • Soluble in: Ethanol, methanol, and other polar organic solvents.
  • Insoluble in: Water and non-polar solvents, as its polarity does not favor interaction with these solvents.

In summary, the solubility of methyl 4-formylbenzoate is significantly affected by its molecular structure and the nature of the solvent, allowing it to dissolve readily in polar environments while remaining insoluble in non-polar conditions. Understanding these properties is essential for utilizing this compound effectively in chemical applications.

Interesting facts

Interesting Facts About Methyl 4-Formylbenzoate

Methyl 4-formylbenzoate is a fascinating compound with significant relevance in various fields of chemistry, particularly in organic synthesis and medicinal chemistry. Here are some intriguing facts about this compound:

  • Structure: Methyl 4-formylbenzoate is derived from benzoic acid and features a formyl group, making it a part of the larger family of aromatic aldehydes and esters. The presence of both the methyl group and the formyl group allows for interesting reactivity.
  • Synthetic Utility: This compound is often utilized in synthetic organic chemistry as a key intermediate in the preparation of more complex molecules. Its unique functional groups allow for various chemical reactions, making it a valuable building block.
  • Applications: Methyl 4-formylbenzoate finds applications in the production of pharmaceuticals, agrochemicals, and dyes. Its versatility and reactivity make it a promising candidate for developing new chemical entities.
  • Biological Activity: Investigations into the biological properties of related compounds have shown that they can exhibit antimicrobial and anti-inflammatory activities. While specific studies on methyl 4-formylbenzoate may be limited, its structural analogs have sparked interest in drug discovery.
  • Literature Research: The compound can be synthesized through various methods, some of which have been documented in scientific literature, highlighting its importance and versatility in modern chemistry.

As a compound, methyl 4-formylbenzoate serves as an excellent example of how simple structures can lead to profound implications in chemical research and application. Its ability to serve as both an intermediate in synthesis and a potential candidate for bioactivity positions it as an intriguing subject for further study.


Synonyms
METHYL 4-FORMYLBENZOATE
1571-08-0
Methyl p-formylbenzoate
4-Carbomethoxybenzaldehyde
Benzoic acid, 4-formyl-, methyl ester
Methyl terephthalaldehydate
4-(Methoxycarbonyl)benzaldehyde
Methyl-p-formyl benzoate
p-Carbomethoxybenzaldehyde
4-Formylbenzoic Acid Methyl Ester
Methyl terephthaldehydate
Methyl benzaldehyde-4-carboxylate
Terephthalaldehydic acid, methyl ester
p-Formylbenzoic acid methyl ester
4-Carboxybenzaldehyde methyl ester
2-Methoxycarbonylbenzaldehyde
NSC 28459
CCRIS 6063
HSDB 5842
EINECS 216-385-5
p-(Methoxycarbonyl)benzaldehyde
DTXSID4025610
NH766742VV
NSC-28459
DTXCID005610
METHYL 4-FORMYLBENZOATE [HSDB]
Methyl pformylbenzoate
pCarbomethoxybenzaldehyde
4Carbomethoxybenzaldehyde
4(Methoxycarbonyl)benzaldehyde
METHYL-P-FORMYLBENZOATE
Methyl benzaldehyde4carboxylate
pFormylbenzoic acid methyl ester
4Carboxybenzaldehyde methyl ester
Benzoic acid, 4formyl, methyl ester
PARA(METHOXYCARBONYL)BENZALDEHYDE
4-FORMYL BENZOIC ACID, METHYL ESTER
216-385-5
inchi=1/c9h8o3/c1-12-9(11)8-4-2-7(6-10)3-5-8/h2-6h,1h
methyl4-formylbenzoate
MFCD00006950
p-Methoxycarbonylbenzaldehyde
methyl-4-formylbenzoate
Terephthalaldehydic Acid Methyl Ester
4-formyl-benzoic acid methyl ester
CAS-1571-08-0
Methyl 4-FormYl-Benzoate
UNII-NH766742VV
methyl p formylbenzoate
Methyl 4-formylbezoate
methyl 4 formylbenzoate
p-carbomethoxybenzaldehye
4-Carbmethoxybenzaldehyde
methyl-4-formyl-benzoate
4-carbomethoxy benzaldehyde
4-methoxycarbonylbenzaldehyde
SCHEMBL79533
4-formyl benzoic acid methyl
MLS002415742
Methyl 4-formylbenzoate, 99%
4-formylbenzoic acid methylester
CHEMBL1607943
methyl 4-formylbenzenecarboxylate
4-HC(O)-C6H4-COOCH3
4-formylbenzoic acid, methyl ester
ALBB-026582
NSC28459
STR02252
Tox21_202369
Tox21_303302
AB9721
BBL011959
STK199271
AKOS000268627
AS-5672
CS-W009013
FM29140
NCGC00091198-01
NCGC00091198-02
NCGC00091198-03
NCGC00091198-04
NCGC00257074-01
NCGC00259918-01
AC-23115
AC-24989
BP-12332
HY-78000
SMR001252203
SY003456
DB-012901
NS00021702
T0012
EN300-15457
Q27284866
Z18297598