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L-16931

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Identification
Molecular formula
C15H22N2O3S
CAS number
123456-78-9
IUPAC name
methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate
State
State

At room temperature, methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate is typically found in a solid state.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.00
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.00
General information
Molecular weight
312.40g/mol
Molar mass
312.4010g/mol
Density
1.2000g/cm3
Appearence

This compound is typically a crystalline solid with a potential color ranging from white to off-white. The appearance can vary depending on purity and specific crystallization conditions.

Comment on solubility

Solubility of Methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate

The solubility of methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate in various solvents is an intriguing topic. This compound is a complex chemical structure, and its solubility profile can be influenced by several factors:

  • Polarity of Solvents: The solubility may vary significantly between polar and non-polar solvents. Typically, compounds with polar functional groups tend to exhibit a higher solubility in polar solvents such as water or ethanol.
  • Hydrogen Bonding: The presence of amino groups in the compound may facilitate hydrogen bonding, enhancing solubility in solvents capable of engaging in such interactions.
  • Temperature Effects: Increasing the temperature often leads to improved solubility, allowing for greater freedom of molecular movement and interaction with the solvent.
  • Concentration Thresholds: At higher concentrations, solubility could decrease due to interactions between solute molecules that may lead to precipitation.

It is essential to consider the comprehensive solubility data and conduct experiments to fully understand how this compound behaves in different environments. While the exact solubility can vary, one can generally predict that due to its complex structure, solubility might not be straightforward. As a general point, "like dissolves like," and thus knowledge of the chemical's functional groups will guide optimal solvent selection.

Interesting facts

Interesting Facts about Methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate

Methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate is a fascinating compound that showcases the unique properties of thiophene derivatives. With its diverse structural features, it is of particular interest in various fields of chemistry and pharmacology.

1. Structural Characteristics

This compound features a thiophene ring, which is a five-membered aromatic ring containing sulfur. The presence of functional groups such as esters and amines enhances its reactivity and potential for forming new compounds. These structural elements contribute to its potential biological activity and interaction with other molecules.

2. Applications in Chemistry and Pharmacology

  • Medicinal Chemistry: The incorporation of amino and carboxyl groups can increase the compound's ability to interact with biological targets, potentially leading to the development of new therapeutic agents.
  • Materials Science: Its unique properties might make it suitable for use in the synthesis of novel materials, particularly in the creation of conductive polymers or specialized coatings.
  • Research: The compound serves as a key intermediate for synthesizing more complex thiophene derivatives, which can be explored for various applications.

3. Synthesis and Reaction Pathways

The synthesis of methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate may involve techniques such as nucleophilic substitution, condensation reactions, and coupling strategies. These methodologies highlight the versatility of thiophene chemistry and contribute to the expanding library of organic compounds available for research.

4. Thriving Research Interest

Researchers are continually uncovering new properties and potential applications of thiophene derivatives. The study of such compounds enriches our understanding of chemical interactions and opens doors to innovative solutions in medicine and materials science. As scientists delve deeper into the characteristics of compounds like methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate, we can anticipate exciting developments on the horizon.


Synonyms
Articaine
23964-58-1
Carticaine
Articaina
Articainum
D3SQ406G9X
DTXSID7048536
methyl 4-methyl-3-[2-(propylamino)propanamido]thiophene-2-carboxylate
2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester
Articadent
Articain
Carticain
Orabloc
Ultacan
Ultacan Forte
methyl 4-methyl-3-(2-(propylamino)propanamido)thiophene-2-carboxylate
Hydrochloride, Carticaine
RefChem:388864
Septocaine and Epinephrine
Articaine HCl and Epinephrine
DTXCID3028003
N01BB08
articaine hydrochloride, epinephrine bitartrate
Articaine Hydrochloride; Epinephrine Bitartrate
Articaine hydrochloride and epinephrine bitartrate
607-295-0
Septocaine
Zorcaine
methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate
MFCD00864454
methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate hydrochloride
methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate
Articaine (INN)
ARTICAINE [INN]
Articaine [INN:BAN]
Articainum [INN-Latin]
Articaina [INN-Spanish]
4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid, methyl ester
UNII-D3SQ406G9X
4-Methyl-3-[2-(propylamino)propionamido]-2-thiophenecarboxylic acid, methyl ester
4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid Methyl Ester; 4-Methyl-3-[2-(propylamino)propionamido]-2-thiophenecarboxylic Acid Methyl Ester (8CI); Articaine; Carticaine
CARTICAINE [MI]
Prestwick0_001032
Prestwick1_001032
Prestwick2_001032
Prestwick3_001032
ARTICAINE [VANDF]
Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat)
ARTICAINE [USP-RS]
ARTICAINE [WHO-DD]
CHEMBL1093
SCHEMBL26715
BSPBio_001243
SPBio_003094
BPBio1_001368
HOE-45
orb1744251
CHEBI:91834
HY-B0516A
ALBB-022443
MSK11362
BBL023182
BDBM50225496
STL290419
AKOS005287449
DB09009
4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester
NCGC00179248-01
AC-27016
SY465997
VS-07343
5378B
AB00514635
CS-0009469
NS00006488
D07468
F88299
AB00514635_06
964A570
964A581
EN300-18562931
Q421297
BRD-A70514680-003-03-9
BRD-A70514680-003-11-2
Methyl 4-methyl-3-([2-(propylamino)propanoyl]amino)-2-thiophenecarboxylate #
METHYL 4-METHYL-3-(2-(PROPYLAMINO)PROPIONAMIDO)-2-THIOPHENECARBOXYLATE
2-thiophenecarboxylic acid, 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-, methyl ester, hydrochloride