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Methyl 4,6-dihydroxy-2-methyl-3,4-dihydroisoquinoline-1-carboxylate

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Identification
Molecular formula
C13H15NO4
CAS number
59839-16-8
IUPAC name
methyl 4,6-dihydroxy-2-methyl-3,4-dihydro-1H-isoquinoline-1-carboxylate
State
State

The compound is usually a solid at room temperature, reflecting its crystalline and stable molecular nature. Due to its polar functional groups, it can exhibit some solubility in organic solvents.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
396.50
Boiling point (Kelvin)
669.70
General information
Molecular weight
249.27g/mol
Molar mass
249.2650g/mol
Density
1.3200g/cm3
Appearence

Methyl 4,6-dihydroxy-2-methyl-3,4-dihydro-1H-isoquinoline-1-carboxylate typically presents as a solid crystalline powder that may take on a light color, often white to off-white. As with many organic compounds, its physical state can give some insight into its purity and chemical nature.

Comment on solubility

Solubility of Methyl 4,6-Dihydroxy-2-methyl-3,4-dihydro-1H-isoquinoline-1-carboxylate

The solubility of methyl 4,6-dihydroxy-2-methyl-3,4-dihydro-1H-isoquinoline-1-carboxylate is an intriguing aspect of its chemical behavior. Understanding its solubility can provide valuable insights into its applications and interactions in various solvents. Here are some key points:

  • Polarity: Given the presence of both hydroxyl groups and a carboxylate moiety, this compound exhibits a degree of polarity which tends to enhance its solubility in polar solvents.
  • Solvent Types:
    • Water: Typically, compounds with multiple hydroxyl groups show better solubility in water.
    • Organic solvents: Depending on its overall hydrophobic characteristics, it may also dissolve in various organic solvents, although less polar solvents might present challenges.
  • pH Influence: The solubility could be affected by the pH of the solution, particularly because a carboxylate can lose or gain protons under different pH conditions, altering its charge and solubility accordingly.

In conclusion, the solubility of methyl 4,6-dihydroxy-2-methyl-3,4-dihydro-1H-isoquinoline-1-carboxylate is influenced by its molecular structure, including the presence of functional groups and the nature of the solvent. As studies continue, a deeper understanding of its solubility can be developed, aiding in its future applications.

Interesting facts

Interesting Facts about Methyl 4,6-Dihydroxy-2-Methyl-3,4-Dihydro-1H-Isoquinoline-1-Carboxylate

Methyl 4,6-dihydroxy-2-methyl-3,4-dihydro-1H-isoquinoline-1-carboxylate is a fascinating compound that belongs to the class of isoquinoline alkaloids. These alkaloids are known not only for their diverse structural characteristics but also for their potential biological activities, making them the focus of extensive research in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Historical Relevance: Isoquinoline alkaloids have been studied for over a century, with many traditional medicines utilizing derivatives for their therapeutic properties.
  • Biological Activity: Compounds related to methyl 4,6-dihydroxy-2-methyl-3,4-dihydro-1H-isoquinoline-1-carboxylate have exhibited a variety of biological effects, such as anti-inflammatory, analgesic, and antioxidant activities.
  • Synthesis Challenges: The synthesis of isoquinoline derivatives often poses significant challenges, requiring multi-step processes that can result in low yields due to the complexity of creating the isoquinoline framework.
  • Research Potential: Ongoing studies aim to explore this compound's pharmacological properties further, potentially leading to the development of new therapeutic agents.

As Dr. H.G. Kwon once stated, "The discovery of new alkaloids often opens doors to new therapeutic pathways." Such compounds often serve as lead compounds in drug development due to their unique arrangements of functional groups that may interact with biological targets.

In conclusion, methyl 4,6-dihydroxy-2-methyl-3,4-dihydro-1H-isoquinoline-1-carboxylate is much more than just a chemical formula; it is a part of a larger narrative in the quest for medicinal advancements.

Synonyms
23824-12-6
1-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-4,6-dihydroxy-2-methyl-, methyl ester
RefChem:1055676
BRN 0485381
4,6-Dihydroxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid methyl ester
1-Isoquinolinecarboxylic acid, 4,6-dihydroxy-2-methyl-1,2,3,4-tetrahydro-, methyl ester
DTXSID10946622
Methyl 4,6-dihydroxy-2-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylate