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Leflunomide

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Identification
Molecular formula
C12H9F3N2O2
CAS number
75706-12-6
IUPAC name
methyl 5-[(1-carbamoyl-3-methyl-butyl)amino]-4-[[2-[[4-(3-methoxy-3-oxo-prop-1-enyl)benzoyl]amino]acetyl]amino]-5-oxo-pentanoate
State
State

At room temperature, Leflunomide is a solid.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
579.00
Boiling point (Kelvin)
852.15
General information
Molecular weight
270.20g/mol
Molar mass
270.2040g/mol
Density
1.3999g/cm3
Appearence

Leflunomide is a white to off-white crystalline powder.

Comment on solubility

Solubility of Methyl 5-[(1-carbamoyl-3-methyl-butyl)amino]-4-[[2-[[4-(3-methoxy-3-oxo-prop-1-enyl)benzoyl]amino]acetyl]amino]-5-oxo-pentanoate

The solubility of methyl 5-[(1-carbamoyl-3-methyl-butyl)amino]-4-[[2-[[4-(3-methoxy-3-oxo-prop-1-enyl)benzoyl]amino]acetyl]amino]-5-oxo-pentanoate (C12H9F3N2O2) can vary significantly based on various factors. Understanding the solubility of this compound is essential for its application in fields such as pharmaceuticals and agrochemicals. Here are some key points to consider:

  • Polarity: The presence of functional groups, particularly those capable of hydrogen bonding, may increase solubility in polar solvents.
  • Temperature: Solubility often increases with temperature; hence, this compound may dissolve better in warmer solvents.
  • Solvent Type: Depending on the solvent, the solubility can be drastically different—apolar solvents may dissolve non-polar portions effectively, while polar solvents may dissolve the more ionic parts.

It is also important to note that precise solubility data can vary based on experimental conditions. Always refer to specific literature for detailed solubility characteristics, as these can be influenced by the presence of other substances or the method of preparation.

In conclusion, determining the solubility of methyl 5-[(1-carbamoyl-3-methyl-butyl)amino]-4-[[2-[[4-(3-methoxy-3-oxo-prop-1-enyl)benzoyl]amino]acetyl]amino]-5-oxo-pentanoate necessitates a comprehensive approach, taking into account various influencing factors to predict behavior in different environments.

Interesting facts

Interesting Facts about Methyl 5-[(1-carbamoyl-3-methyl-butyl)amino]-4-[[2-[[4-(3-methoxy-3-oxo-prop-1-enyl)benzoyl]amino]acetyl]amino]-5-oxo-pentanoate

Methyl 5-[(1-carbamoyl-3-methyl-butyl)amino]-4-[[2-[[4-(3-methoxy-3-oxo-prop-1-enyl)benzoyl]amino]acetyl]amino]-5-oxo-pentanoate is a fascinating compound that belongs to a complex class of chemical entities with noteworthy applications in medicinal chemistry. Here are some intriguing facts about this compound:

  • Multifunctional Potential: The compound is structured to potentially target multiple biological mechanisms, making it a candidate for research in drug development.
  • Structure-Activity Relationship (SAR): Its unique functional groups may allow for the investigation of SAR, which is crucial in understanding how the structure of a compound affects its biological activity.
  • Applications: This compound could play a role in developing therapeutic agents due to its ability to interact with specific biological targets. It might lead to advancements in treatments for various conditions.
  • Analytical Techniques: Studying this compound requires advanced analytical techniques like NMR, LC-MS, and IR spectroscopy to confirm its structure and understand its properties.
  • Innovative Research: Chemists and biologists might engage in interdisciplinary collaborations to explore its pharmacokinetics and pharmacodynamics, paving the way for new drug formulations.

As a complex molecule, it exemplifies the intricate relationships within medicinal chemistry where a minute change in structure can significantly impact the efficacy and safety of potential pharmaceuticals. The ongoing exploration of such compounds could not only enhance our understanding of chemistry but also lead to groundbreaking therapeutic solutions.