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Lidocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
methyl 5-(dimethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate
State
State

At room temperature, lidocaine is usually found in a solid state as a powder, but it can also be dissolved in solution for medical use.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3430g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is typically a white to slightly yellowish crystalline powder. It is practically odorless and has a slightly bitter taste.

Comment on solubility

Solubility of Methyl 5-(dimethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate

Methyl 5-(dimethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate is an intriguing compound that displays a specific solubility profile influenced by its structural characteristics. Understanding its solubility can be essential for applications in various chemical processes. Here are some key points to consider:

  • Solubility in Organic Solvents: This compound tends to be soluble in a range of organic solvents due to the presence of non-polar hydrocarbon chains and aromatic groups. Common solvents include:
    • Ethyl acetate
    • Toluene
    • Hexane
  • Limited Aqueous Solubility: Given its hydrophobic characteristics, the compound displays limited solubility in water. This is typical for most organic compounds with significant non-polar regions.
  • Influence of Temperature: Solubility may vary with temperature, showing increased solubility in organic solvents when heated, which enhances molecular interactions.
  • pH Sensitivity: The presence of a dimethylamino group may cause the solubility to change with pH adjustments, potentially forming soluble ionic species under certain conditions.

In summary, the solubility of methyl 5-(dimethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate in organic solvents positions it advantageously for many applications, while its limited aqueous solubility indicates caution for use in aqueous environments. Understanding these properties can aid chemists in effectively utilizing this compound.

Interesting facts

Interesting Facts about Methyl 5-(dimethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate

Methyl 5-(dimethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate is a remarkable compound with various intriguing properties and applications. Here are some captivating facts about this compound:

  • Pharmacological Potential: This compound falls within the category of pharmaceutical intermediates, indicating its significance in the synthesis of potential therapeutic agents. The presence of the dimethylamino group may contribute to its biological activity.
  • Structural Complexity: The structure of this molecule is quite intricate, featuring several functional groups that can affect its reactivity and interaction with biological systems. Its naphthyl moiety can enhance lipophilicity, which may lead to improved membrane permeability in drug formulations.
  • Isopropyl Influence: The isopropyl group often imparts unique steric effects that can stabilize certain conformations of the molecule, potentially influencing its bioactivity and interaction with enzymes or receptors.
  • Applications in Synthesis: Methyl esters, such as this compound, are frequently utilized in organic synthesis and can serve as useful building blocks in the development of more complex molecules.
  • Research Interest: Ongoing research may uncover additional properties, making this compound a subject of interest in both academic and industrial settings.

In conclusion, the study of methyl 5-(dimethylamino)-2-isopropyl-2-(1-naphthyl)pentanoate showcases how intricate molecular design can lead to significant scientific advancements. As researchers continue to explore its potential, this compound might play a crucial role in the development of new pharmaceutical products.

Synonyms
6699-15-6
alpha-(3-(Dimethylamino)propyl)-alpha-isopropyl-1-naphthaleneacetic acid methyl ester
BRN 2765263
1-Naphthaleneacetic acid, alpha-(3-(dimethylamino)propyl)-alpha-isopropyl-, methyl ester
DTXSID70985799
methyl 5-(dimethylamino)-2-(naphthalen-1-yl)-2-(propan-2-yl)pentanoate