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Methyl 6-fluorohexanoate

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Identification
Molecular formula
C7H13FO2
CAS number
334-68-9
IUPAC name
methyl 6-fluorohexanoate
State
State

At room temperature, methyl 6-fluorohexanoate remains in a liquid state.

Melting point (Celsius)
-2.00
Melting point (Kelvin)
271.15
Boiling point (Celsius)
162.00
Boiling point (Kelvin)
435.15
General information
Molecular weight
148.18g/mol
Molar mass
148.1750g/mol
Density
1.0055g/cm3
Appearence

Methyl 6-fluorohexanoate is typically a colorless liquid with a faint, sweet ester-like odor. It is clear and free from any suspended matter.

Comment on solubility

Solubility of Methyl 6-Fluorohexanoate

Methyl 6-fluorohexanoate, with the chemical formula C7H13F O2, exhibits distinct solubility characteristics that can be quite interesting for various applications.

Generally, the solubility of this compound can be summarized as follows:

  • Polar vs. Non-Polar Solvents: Methyl 6-fluorohexanoate is likely more soluble in non-polar solvents. This is due to the hydrocarbon chain that dominates its structure, which typically favors interactions with other hydrophobic substances.
  • Water Solubility: The water solubility of this compound is expected to be low. The presence of the fluoro group may lend some polar characteristics but probably not enough to significantly enhance solubility in water.
  • Influence of Functional Groups: The structure comprises an ester functional group, which can participate in hydrogen bonding. This property may allow it to exhibit minor solubility in polar solvents compared to completely non-polar compounds.

In practical usage, consider the following:

  • In organic synthesis, using organic solvents (like hexane or dichloromethane) would enhance the solubility of methyl 6-fluorohexanoate.
  • For formulations in pharmaceuticals or agrochemicals, assessing solubility in various media can guide the choice of solvents or emulsifiers.

In summary, while methyl 6-fluorohexanoate may be less soluble in water, its solubility in organic solvents is noteworthy and can vary based on environmental conditions and solvent choice. This characteristic can crucially impact its functionality in different chemical processes.

Interesting facts

Interesting Facts about Methyl 6-Fluorohexanoate

Methyl 6-fluorohexanoate is a unique organic compound that belongs to the ester family. Esters often capture the imagination of chemists due to their diverse applications and interesting properties.

  • Structure and Function: This compound consists of a six-carbon chain with a fluoro substituent on the sixth carbon, making it a fluorinated organic molecule. The presence of fluorine can significantly affect the reactivity and stability of the compound, opening doors to various chemical applications.
  • Applications: Methyl 6-fluorohexanoate is utilized in the synthesis of pharmaceutical intermediates and agrochemicals. Its fluorinated structure may enhance the activity and selectivity of biological agents, contributing to advancements in drug design.
  • Reactivity: The fluoro group is known for imparting unique chemical properties that may lead to increased lipophilicity and metabolic stability. This can make fluorinated compounds more resistant to enzymatic degradation, which is especially beneficial in medicinal chemistry.
  • Flavor and Fragrance: Some esters are recognized for their delightful scents. While there’s limited information about the olfactory properties of methyl 6-fluorohexanoate specifically, many similar compounds contribute to the aroma of fruits and flowers.
  • Environmental Impact: As with many fluorinated compounds, it's essential to consider the environmental implications. Chemists are continuously investigating methods to mitigate any negative effects while harnessing their useful properties in various industries.

In conclusion, methyl 6-fluorohexanoate stands as a testament to the fascinating world of organic chemistry, showcasing how small changes in molecular structure can lead to significant variations in behavior and application. As research continues, who knows what new discoveries await in the realm of fluorinated compounds!

Synonyms
Methyl 6-fluorohexanoate
6-Fluorohexanoic acid methyl ester
333-07-3
Methyl omega-fluorohexanoate
HEXANOIC ACID, 6-FLUORO-, METHYL ESTER
BRN 1752061
DTXSID10186920
starbld0045450
SCHEMBL11446391
DTXCID50109411