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Praziquantel

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Identification
Molecular formula
C19H24N2O2
CAS number
55268-74-1
IUPAC name
methyl 7-(diethylamino)-4-oxo-6-propyl-1H-quinoline-3-carboxylate
State
State

Praziquantel is in a solid state at room temperature, typically presented as a crystalline powder. It is stable under normal conditions and needs to be protected from excessive heat and moisture to maintain its efficacy.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
312.41g/mol
Molar mass
312.4110g/mol
Density
1.2300g/cm3
Appearence

Praziquantel appears as a white to pale cream, odorless crystalline powder. It is typically available in a solid form and may sometimes be offered in powdered or tablet formulations. Its crystalline nature makes it reflect light, giving it a shiny appearance.

Comment on solubility

Solubility of Methyl 7-(Diethylamino)-4-oxo-6-propyl-1H-quinoline-3-carboxylate

Methyl 7-(diethylamino)-4-oxo-6-propyl-1H-quinoline-3-carboxylate is a complex organic compound whose solubility can be influenced by a variety of factors. Generally, the solubility of such compounds is governed by the following key considerations:

  • Polarity: The presence of polar functional groups, such as carboxylate, can enhance solubility in polar solvents like water.
  • Hydrophobic Regions: The hydrocarbon portions of the molecule may exhibit low solubility in water but better solubility in non-polar solvents like hexane.
  • Temperature: Increasing the temperature often improves solubility, as the kinetic energy facilitates interactions between solute and solvent molecules.
  • pH Influence: The protonation state of the amine group might change in different pH environments, potentially affecting solubility in aqueous solutions.

In summary, the solubility of methyl 7-(diethylamino)-4-oxo-6-propyl-1H-quinoline-3-carboxylate can be complex and context-dependent. To assess its solubility more thoroughly, one should consider the particular solvent system in use, as well as the temperature and pH conditions, which can significantly alter the compound's behavior. As with many organic compounds, the interaction between solute and solvent plays a crucial role, making empirical solubility testing essential in practical applications.

Interesting facts

Interesting Facts about Methyl 7-(diethylamino)-4-oxo-6-propyl-1H-quinoline-3-carboxylate

Methyl 7-(diethylamino)-4-oxo-6-propyl-1H-quinoline-3-carboxylate is a fascinating compound known for its versatile applications in the field of organic chemistry and medicinal research. Here are some intriguing aspects to consider:

  • Quinoline Derivative: This compound belongs to the quinoline class, which is known for its diverse biological activities. Quinoline derivatives have been explored for their potential as antimicrobial, antimalarial, and anticancer agents.
  • Biological Relevance: Due to its unique structure, this compound may exhibit interesting pharmacological properties. Scientists continue to research its effects on different biological targets, opening doors for potential therapeutic applications.
  • Structure-Activity Relationship (SAR): The specific arrangement of the diethylamino group, propyl side chain, and the carboxylate moiety can significantly influence the compound's activity, allowing chemists to design new derivatives with enhanced efficacy.
  • Synthetic Pathways: The synthesis of this compound involves several steps, which may include condensation reactions and modifications typical for quinoline derivatives, making it a subject of interest in synthetic organic chemistry.
  • Research Applications: Researchers use this compound as a building block in the development of other more complex structures, often leading to the discovery of new drugs or chemical probes in biological studies.

In summary, methyl 7-(diethylamino)-4-oxo-6-propyl-1H-quinoline-3-carboxylate showcases the interplay between structure and function in medicinal chemistry. As stated by prominent chemists, “The essence of chemistry lies in the manipulation of atoms to solve real-world problems.” This compound exemplifies that essence, paving the way for future discoveries.

Synonyms
AMQUINATE
17230-85-2
Amquinolate
Amquinatum
Anquinato
NSC-339053
Methyl 7-(diethylamino)-4-hydroxy-6-propyl-3-quinolinecarboxylate
21N28Z70CI
DTXSID10169253
3-Quinolinecarboxylic acid 7-(diethylamino)-4-hydroxy-6-propyl-, methyl ester
7-Diethylamino-4-hydroxy-6-propyl-3-quinolinecarboxylic acid methyl ester
DTXCID8091744
NSC339053
Methyl 7-(diethylamino)-4-hydroxy-6-propylquinoline-3-carboxylate
methyl 7-(diethylamino)-4-oxo-6-propyl-1H-quinoline-3-carboxylate
3-Quinolinecarboxylic acid, 7-(diethylamino)-4-hydroxy-6-propyl-, methyl ester
Amquinato
Amquinate (USAN/INN)
Amquinate [USAN:INN]
Amquinatum [INN-Latin]
Amquinato [INN-Spanish]
UNII-21N28Z70CI
NSC 339053
AMQUINATE [INN]
AMQUINATE [USAN]
SCHEMBL537649
CHEMBL2104009
SB72134
DA-43525
NS00124244
D02930
Q27253562
methyl 7-(diethylamino)-4-hydroxy-6-propyl-quinoline-3-carboxylate
Methyl7-(diethylamino)-4-hydroxy-6-propylquinoline-3-carboxylate