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Methyl benzimidazolecarbamate

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Identification
Molecular formula
C15H21N3O2
CAS number
10605-21-7
IUPAC name
methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate
State
State

At room temperature, this compound is in a solid state.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
363.00
Boiling point (Kelvin)
636.15
General information
Molecular weight
314.40g/mol
Molar mass
314.3970g/mol
Density
1.3000g/cm3
Appearence

The compound generally appears as a white crystalline powder.

Comment on solubility

Solubility of Methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate

The solubility of methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate in various solvents is a critical factor that influences its utility in both laboratory and industrial applications. Understanding its solubility can be framed through the following considerations:

  • Polar Solvents: Typically, compounds featuring polar functional groups exhibit higher solubility in polar solvents such as water and methanol. However, the hydrophobic butyl group in this compound may hinder its overall solubility in highly polar mediums.
  • Non-Polar Solvents: On the other hand, methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate may demonstrate improved solubility in non-polar solvents due to the presence of the alkyl chain, which enhances hydrophobic interactions.
  • Temperature Influence: The solubility of many chemical compounds strongly depends on temperature; as the temperature increases, solubility often increases as well.
  • pH Dependence: Being a carbamate, the solubility may also be influenced by the pH of the solution. Typically, a more alkaline environment may lead to greater solubility due to deprotonation.

In summary, while it is tempting to generalize, the solubility of methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate should be evaluated within the context of the solvent's characteristics, temperature variances, and the pH of the solution. Understanding these interactions is key to maximizing the compound’s effectiveness in practical applications.

Interesting facts

Interesting Facts about Methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate

Methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate is a fascinating compound with varied applications in the field of chemistry and beyond. Here are some compelling points to consider:

  • Biological Activity: This compound exhibits notable biological properties, making it an area of interest for researchers in medicinal chemistry. Compounds similar to it have been studied for potential anti-cancer and anti-inflammatory effects.
  • Structure-Activity Relationship: The unique structure of this compound, particularly the benzimidazole moiety, plays a crucial role in its interaction with biological targets. Understanding these interactions can lead to the development of more effective therapeutic agents.
  • Agrochemical Potential: Compounds like methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate are often explored for their potential use in agrochemicals, such as fungicides and pest control agents. Their ability to inhibit specific enzymes in pests holds the promise of developing more efficient agricultural solutions.
  • Research Applications: Due to its structural characteristics, the compound serves as a valuable tool in biochemical research, allowing scientists to elucidate biological pathways and mechanisms.
  • Innovation in Synthesis: The synthesis of this compound can involve advanced organic chemistry techniques, showcasing the creativity and innovation within the field. Chemists continuously seek novel methods to improve yield and reduce environmental impact during synthesis.

In summary, methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate not only represents a compelling subject of study but also embodies the potential for significant contributions to medicine and agriculture. As researchers continue to explore its properties, this compound could pave the way for exciting advancements in various sectors.

Synonyms
Parbendazole
14255-87-9
Worm Guard
Verminum
Parbendazol
Helatac
PBDZ
Parbendazolum
SK&F 29044
TCMDC-131798
METHYL 5-BUTYL-2-BENZIMIDAZOLECARBAMATE
Carbamic acid, (5-butyl-1H-benzimidazol-2-yl)-, methyl ester
N4X8WVX2UG
5-Butyl-2-(carbomethoxyamino)benzimidazole
SKF-29044
NSC-256420
DTXSID0045410
2-Benzimidazolecarbamic acid, 5-butyl-, methyl ester
(4-Butyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester
DTXCID8025410
SK&F-29044
238-133-3
Methyl (5-butyl-1H-benzo[d]imidazol-2-yl)carbamate
Helmatac
SKF 29044
methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate
Parbendazole free base
5-Butyl-2-benzimidazolecarbamic acid methyl ester
14255-87-9 (free base)
MFCD00864534
NCGC00016706-01
CAS-14255-87-9
methyl ~{N}-(5-butyl-1~{H}-benzimidazol-2-yl)carbamate
N-(6-Butyl-1H-benzimidazol-2-yl)carbamic Acid Methyl Ester
Parbendazol [INN-Spanish]
Parbendazolum [INN-Latin]
EINECS 238-133-3
UNII-N4X8WVX2UG
Parbendazole?
Parbendazole [USAN:INN:BAN]
Parbendazole (Standard)
N-(Butyl-5, benzimidazolyl)-2, carbamate de methyle [French]
Methyl 5(6)-butyl-2-benzimidazolecarbamate
Prestwick0_001110
Prestwick1_001110
Prestwick2_001110
Prestwick3_001110
PARBENDAZOLE [MI]
Parbendazole (USAN/INN)
PARBENDAZOLE [INN]
PARBENDAZOLE [USAN]
BSPBio_001220
PARBENDAZOLE [USP-RS]
SCHEMBL259455
SCHEMBL259456
SPBio_003090
BPBio1_001342
CHEMBL528271
N-(Butyl-5, benzimidazolyl)-2, carbamate de methyle
orb1301100
SCHEMBL27363030
SCHEMBL29409286
CHEBI:94267
YRWLZFXJFBZBEY-UHFFFAOYSA-N
HMS1571M22
HMS2098M22
HMS3715M22
PAA25587
Tox21_110571
MSK001630
NSC256420
s2444
WLN: T56 BM DNJ CMVO1 G4
AKOS015898352
AKOS015967508
Tox21_110571_1
2H-Benzimidazole, carbamic acid deriv.
AC-1936
CCG-221110
HY-115364R
NSC 256420
Methyl 5-butylbenzimidazole-2-carbamate
NCGC00016706-02
NCGC00016706-03
NCGC00016706-04
NCGC00016706-05
NCGC00016706-07
AS-68370
2-carbomethoxyamino-5-n-butylbenzimidazole
HY-115364
AB00514054
CS-0035171
NS00024636
methyl 5-butyl-1H-benzimidazol-2-ylcarbamate
D05365
F18423
Parbendazole, VETRANAL(TM), analytical standard
Methyl 5-butyl-1H-benzo[d]imidazol-2-ylcarbamate
methyl N-(5-butyl-1H-benzimidazol-2-yl)carbamate
SR-01000872691
(5-Butyl-2-benzimidazole)carbamic acid methyl ester
Methyl (6-butyl-1H-benzo[d]imidazol-2-yl)carbamate
SR-01000872691-1
BRD-K02407574-001-03-0
BRD-K02407574-001-04-8
BRD-K02407574-001-06-3
BRD-K02407574-001-09-7
Q27166068
METHYL N-(5-BUTYL-1H-1,3-BENZODIAZOL-2-YL)CARBAMATE
Parbendazole, United States Pharmacopeia (USP) Reference Standard
CARBAMIC ACID, N-(6-BUTYL-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER
H1C