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Methysulfate / Trospium Chloride

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Identification
Molecular formula
C25H43NO6S
CAS number
10405-02-4
IUPAC name
methyl sulfate;trimethyl-[3-(1,3,8,8-tetramethyl-3-azoniabicyclo[3.2.1]octan-3-yl)propyl]ammonium
State
State

At room temperature, Trospium chloride is generally found in a solid crystalline state.

Melting point (Celsius)
202.00
Melting point (Kelvin)
475.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
427.61g/mol
Molar mass
427.6080g/mol
Density
1.2500g/cm3
Appearence

Trospium chloride, commonly known as Methysulfate, appears as a white or almost white crystalline solid. It is odorless and hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of Trimethyl-[3-(1,3,8,8-tetramethyl-3-azoniabicyclo[3.2.1]octan-3-yl)propyl]ammonium Methyl Sulfate

The solubility of trimethyl-[3-(1,3,8,8-tetramethyl-3-azoniabicyclo[3.2.1]octan-3-yl)propyl]ammonium methyl sulfate is influenced by its unique structural characteristics and ionic nature. This compound can generally be categorized as a quaternary ammonium salt, known for its ability to dissolve in polar solvents. Here are some important points regarding its solubility:

  • Polar Solvents: It is highly soluble in water due to the ionic interaction between the methyl sulfate anion and the cationic portion of the molecule.
  • Hydrogen Bonding: The presence of functional groups can facilitate hydrogen bonding, which often enhances solubility in polar solvents such as alcohols.
  • Non-polar Solvents: It has limited solubility in non-polar solvents, which is typical for ionic compounds. The absence of charge interactions in non-polar environments results in relatively poor solubility.

In summary, the solubility of trimethyl-[3-(1,3,8,8-tetramethyl-3-azoniabicyclo[3.2.1]octan-3-yl)propyl]ammonium methyl sulfate is strongly dependent on its ionic structure, making it significantly soluble in water and polar solvents while exhibiting greatly reduced solubility in non-polar solvents. As a result, understanding its solubility characteristics is crucial for applications in various chemical and industrial processes.

Interesting facts

Interesting Facts about Trimethyl-3-(1,3,8,8-tetramethyl-3-azoniabicyclo[3.2.1]octan-3-yl)propyl Methyl Sulfate

This compound, known as trimethyl-3-(1,3,8,8-tetramethyl-3-azoniabicyclo[3.2.1]octan-3-yl)propyl methyl sulfate, is noteworthy due to its unique structure and potential applications. Here are some engaging highlights about this fascinating chemical:

  • Cationic Nature: Being quaternary ammonium, this compound carries a positive charge. This cationic character often makes it useful in a variety of applications, particularly in the field of surfactants and as a chemical in formulations.
  • Role in Organic Synthesis: The structure of the compound suggests it could play a significant role in organic synthesis reactions. Its ability to function as a nucleophile or electrophile could be harnessed for creating diverse organic molecules.
  • Potential Biological Applications: Compounds like this one have been noted for their potential biological activity. They might exhibit interesting antimicrobial properties or could be studied for their ability to penetrate biological membranes.
  • Stability and Reactivity: The bicyclic structure provides stability against degradation, which is crucial for many practical applications. Understanding the reactivity of such compounds can lead to novel uses in drug delivery systems.

As this compound contains a bicyclic structure, chemists are often intrigued by its geometric properties and implications for molecular interactions. The unique arrangement of atoms allows for a variety of *steric* and *electronic* factors that influence how it behaves in different environments. Researchers are continually exploring its properties to unlock further applications in medicinal chemistry and materials science.

In summary, trimethyl-3-(1,3,8,8-tetramethyl-3-azoniabicyclo[3.2.1]octan-3-yl)propyl methyl sulfate is not only a compound of interest due to its complex structure but also represents the vast possibilities within the domain of chemical synthesis and application. As scientists probe deeper into this realm, they may uncover even more about the potential of such compounds.

Synonyms
Trimethidinium methosulfate
Camphidonium
TRIMETHIDINIUM METHOSULPHATE
C1O32IJ4HS
Metosulfato de trimetidinio
Methosulfate de trimethidinium
trimethidinii methosulfas
237-994-2
methyl sulfate;trimethyl-(3-(3,5,8,8-tetramethyl-3-azoniabicyclo(3.2.1)octan-3-yl)propyl)azanium
14149-43-0
Trimethidinium methyl sulfate
DTXSID8046115
Ostensin
Euprex
1,3,8,8-Tetramethyl-3-(3-(trimethylammonio)propyl)-3-azoniabicyclo(3.2.1)octane bis(methyl sulfate)
Trimethidinium methosulfate [INN]
NCGC00160374-01
EINECS 237-994-2
HA 106
UNII-C1O32IJ4HS
WY-1395
Wy 1395
Trimethidinium methosulfate [INN:NF]
Trimethidinium-methosulfat
N-(3-Trimethylammoniumpropyl)-N-methylcamphidinium bis(methylsulfate)
N-(gamma-Trimethylammoniumpropyl)-N-methyl-camphidinium-dimethylsulphate
3-(3-(Dimethylamino)propyl)-1,3,8,8-tetramethyl-3-azoniabicyclo(3.2.1)octane methyl sulfate
SCHEMBL309185
CHEMBL2107688
DTXCID6026115
METHOCAMPHONE METHYLSULFATE
ZOSQTCOGKFRDET-UHFFFAOYSA-L
Tox21_111770
TRIMETHIDINIUM METHOSULFATE [MI]
TRIMETHIDINIUM METHOSULFATE [JAN]
3-Azoniabicyclo(3.2.1)octane, 1,3,8,8-tetramethyl-3-(3-(trimethylammonio)propyl)-, bis(methyl sulfate)
METHYL SULFATE;TRIMETHYL-[3-(1,3,8,8-TETRAMETHYL-3-AZONIABICYCLO[3.2.1]OCTAN-3-YL)PROPYL]AZANIUM
S,S'-Dimethyl 1,3,8,8-tetramethyl-3-(3-(trimethylammonio)propyl)-3-azoniabicyclo(3.2.1)octane disulphate
CAS-14149-43-0
NS00024586
Q27275063