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Iopamidol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
methyl(2,3,4,5,6-pentahydroxyhexyl)ammonium;2-[2,4,6-triiodo-3,5-bis(methylcarbamoyl)phenoxy]butanoate
State
State

At room temperature, Iopamidol usually exists as a solid in the form of a crystalline powder.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
777.09g/mol
Molar mass
777.0880g/mol
Density
1.4479g/cm3
Appearence

Iopamidol is a white to off-white crystalline powder that is odorless. It is soluble in water, forming a clear and colorless solution.

Comment on solubility

Solubility of Methyl(2,3,4,5,6-pentahydroxyhexyl)ammonium; 2-[2,4,6-triiodo-3,5-bis(methylcarbamoyl)phenoxy]butanoate

This compound presents a complex structure that influences its solubility in various solvents. The presence of multiple hydroxyl (-OH) groups in the methyl(2,3,4,5,6-pentahydroxyhexyl)ammonium portion suggests that it may be more soluble in polar solvents, such as water or alcohols, due to hydrogen bonding capabilities.

On the other hand, the presence of **lipophilic** components from the 2-[2,4,6-triiodo-3,5-bis(methylcarbamoyl)phenoxy]butanoate side may impart some degree of **hydrophobicity**, potentially leading to a heterogeneous solubility profile. Key factors affecting solubility include:

  • Temperature: Higher temperatures generally increase solubility for many compounds.
  • pH of the solution: The ionization of ammonium groups can be affected by the acidity or basicity of the solution.
  • Solvent polarity: The balance between polarity and non-polar segments will determine the solubility in different mixtures.

In practice, **mixing with polar solvents** will likely enhance its solubility due to the presence of multiple functional groups supporting interactions with water molecules. However, to achieve the desired solubility, careful consideration must be taken regarding the solvent system.

Thus, understanding the solubility of this compound can be essential for various applications, specifically in formulations that rely on its effective dispersal in a solvent system.

Interesting facts

Interesting Facts about Methyl(2,3,4,5,6-pentahydroxyhexyl)ammonium; 2-[2,4,6-triiodo-3,5-bis(methylcarbamoyl)phenoxy]butanoate

This compound represents a fascinating blend of properties that highlight the intricate world of chemical interactions. Here are some intriguing aspects of this compound:

  • Multi-functional Applications: The presence of hydroxyl groups suggests that this compound may exhibit high reactivity with various biological substrates, acting as a potential drug delivery system.
  • Elements of Design: The triiodinated phenoxy group demonstrates how iodine can enhance the compound's radio-logging properties, making it useful in medical imaging techniques.
  • Potential Therapeutic Uses: Compounds with such structures are often explored for their medicinal properties, particularly in the fields of oncology and therapeutic agents.
  • Structural Complexity: The pentahydroxyhexyl portion illustrates the complexity one can achieve in synthetic organic chemistry, promoting solubility and stability in biological environments.
  • Environmental Impact: The incorporation of iodine highlights the ongoing research into environmentally-friendly alternatives in pharmaceuticals and organic compounds.

Overall, this compound showcases the harmony of chemistry and biology, paving the way for innovative solutions to contemporary health challenges. As scholar Robert H. Grubbs once stated, "Chemistry is a waiting game, and nature has given us a rich set of molecules to explore." The journey of understanding this compound is surely filled with potential and discovery!

Synonyms
19080-47-8
RefChem:331235
C14H15I3N2O5.C7H17NO5