Skip to main content

Morpholine-4-carbaldehyde

ADVERTISEMENT
Identification
Molecular formula
C5H9NO2
CAS number
4394-85-8
IUPAC name
morpholine-4-carbaldehyde
State
State

At room temperature, Morpholine-4-carbaldehyde is in a liquid state. It is stable under normal conditions but can polymerize or react with oxidizing agents under certain circumstances.

Melting point (Celsius)
-12.00
Melting point (Kelvin)
261.15
Boiling point (Celsius)
247.00
Boiling point (Kelvin)
520.15
General information
Molecular weight
101.12g/mol
Molar mass
101.1230g/mol
Density
1.0950g/cm3
Appearence

Morpholine-4-carbaldehyde is a clear, colorless to slightly yellow liquid. It has a characteristic odor that is slightly fruity and pungent. The compound is typically available in liquid form due to its relatively low melting point and is miscible with water and organic solvents.

Comment on solubility

Solubility of Morpholine-4-Carbaldehyde

Morpholine-4-carbaldehyde, with the chemical formula C5H9NO, exhibits interesting solubility properties that are worth noting. This compound is generally known to be soluble in various solvents, which broadens its applications in different chemical processes.


Key Solubility Characteristics:

  • Water Solubility: Morpholine-4-carbaldehyde is soluble in water, attributed to the presence of its polar functional groups.
  • Organic Solvents: It is also soluble in organic solvents such as ethanol, methanol, and chloroform, allowing for versatility in experimental conditions.
  • Temperature Dependence: The solubility can increase with temperature, making it easier to dissolve in hotter solvent mixtures.

In practical terms, its solubility characteristics facilitate its use in various industrial and research applications. As we consider its use, it is essential to remember that solubility can significantly impact reactivity and bioavailability.

Interesting facts

Interesting Facts about Morpholine-4-Carbaldehyde

Morpholine-4-carbaldehyde is a fascinating compound, often studied in the field of organic chemistry due to its unique structure and versatile applications. Below are some intriguing aspects of this compound:

  • Structurally Unique: The presence of both a morpholine ring and an aldehyde functional group makes this compound significant. The morpholine ring contributes to its heterocyclic nature, providing interesting properties such as increased stability.
  • Reactivity: Morpholine-4-carbaldehyde acts as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. The aldehyde group can participate in diverse chemical reactions, such as nucleophilic addition reactions and condensation reactions, making it a valuable resource for synthetic chemists.
  • Biological Activity: Compounds containing the morpholine structure are often associated with significant biological activity. Morpholine derivatives have shown potential as drugs, exhibiting anti-inflammatory, analgesic, and antimicrobial properties.
  • Industrial Applications: Beyond the laboratory, morpholine-4-carbaldehyde has practical applications in the formulation of agrochemicals, dyestuffs, and as a building block for synthesizing polymers and coatings.
  • Safety Considerations: As with many organic compounds, it is essential to handle morpholine-4-carbaldehyde with care. Ensure proper safety protocols are in place as exposure could lead to irritation.

In conclusion, morpholine-4-carbaldehyde stands out as a prime example of how a simple molecular structure can lead to complex behaviors and numerous applications in both academic and industrial settings.

Synonyms
4-Formylmorpholine
4394-85-8
morpholine-4-carbaldehyde
N-FORMYLMORPHOLINE
4-Morpholinecarboxaldehyde
formyl morpholine
UNII-D1E63XO4RH
NSC 14833
BRN 0110293
AI3-02845
1-formylmorpholine
EINECS 224-518-3
D1E63XO4RH
DTXSID7044427
NSC-14833
DTXCID5024427
N-MORPHOLINECARBOXALDEHYDE
EC 224-518-3
NFormylmorfolin
NFormylmorpholine
Morpholine, 4formyl
4Morpholinecarbaldehyde
Morpholine4carbaldehyde
4Morpholinecarboxaldehyde
FORMYL MORPHOLINE [INCI]
224-518-3
4-27-00-00274 (beilstein handbook reference)
inchi=1/c5h9no2/c7-5-6-1-3-8-4-2-6/h5h,1-4h
lcedqnddfocwgg-uhfffaoysa-n
Morpholine, 4-formyl-
N-Formylmorfolin
MFCD00006170
N-Formylmorpholine-13C
4-Morpholinecarbaldehyde
N-formyl morpholine
N-Formylmorfolin [Czech]
N-formyhnorpholine
N-Formyl Morpholin
(morpholino)methanone
morpholin-4-yl-methanone
morpholine-4-carboaldehyde
4-Formylmorpholine, 99%
4-Morpholinecarbaldehyde #
morpholine-4-carboxaldehyde
formylmorpholine
4-formyl morpholine
4-formyl-morpholine
Molsidomine impurity D
SCHEMBL7321
NSC14833
Tox21_302027
STL453676
AKOS000121906
AC-7190
CS-W016603
FF36650
s12160
NCGC00255758-01
DS-14377
SY004785
4-Morpholinecarbaldehyde N-Formylmorpholine
4-morpholinecarbaldehyde;n-formylmorpholine
CAS-4394-85-8
DB-070491
F0157
NS00006944
EN300-29852
Molsidomine Imp. D (EP); Molsidomine Impurity D
Q27275975
F8880-0659
Z295197308
Molsidomine impurity D, European Pharmacopoeia (EP) Reference Standard