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Morpholinylmethanone

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Identification
Molecular formula
C17H18N2O2
CAS number
23494-57-0
IUPAC name
morpholino(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)methanone
State
State

At room temperature, Morpholinylmethanone is a solid. Its crystalline nature allows it to be stable under standard conditions.

Melting point (Celsius)
201.50
Melting point (Kelvin)
474.70
Boiling point (Celsius)
435.30
Boiling point (Kelvin)
708.50
General information
Molecular weight
274.34g/mol
Molar mass
274.3370g/mol
Density
1.2212g/cm3
Appearence

Morpholinylmethanone appears as a crystalline powder with a pale yellow to off-white hue. In its pure form, it is typically odorless.

Comment on solubility

Solubility of Morpholino(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)methanone

The solubility of morpholino(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)methanone is a topic of interest due to its unique structural characteristics. This compound's solubility can be influenced by several factors, which include:

  • Polarity: Overall polarity plays a significant role in solubility. Polar solvents tend to dissolve polar compounds while non-polar solvents do the same for non-polar compounds.
  • Hydrogen Bonding: The presence of functional groups capable of forming hydrogen bonds can enhance solubility in polar solvents.
  • Temperature: Increasing temperature often results in increased solubility for many solid compounds.
  • pH Levels: The solubility of certain compounds, particularly those that can ionize, can be highly dependent on the pH of the solution.

As a general observation, compounds with a complex cyclic structure like this one may exhibit limited solubility in water, yet may dissolve well in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
Understanding its solubility characteristics is crucial not only for synthesis but also for applications in fields such as pharmacology, where it may affect bioavailability and therapeutic efficacy.

Interesting facts

Exploring the Compound: Morpholino(7,8,9,10-tetrahydro-6H-cycloheptabquinolin-11-yl)methanone

This intriguing compound belongs to a class of molecules known for their significant potential in pharmacology and medicinal chemistry. Morpholino derivatives, in general, are well-regarded for their ability to enhance the cellular uptake of nucleotides, making them valuable in genetic research.

Key Characteristics:

  • Versatile Applications: Morpholino compounds have garnered attention for their roles in drug development, especially in the targeting of antisense oligonucleotides, which can modulate gene expression.
  • Structural Complexity: The unique cyclic structure of the cyclohepta[b]quinoline moiety contributes to interesting interactions with biological systems, often enhancing selectivity and efficacy of therapeutic agents.
  • Binding Affinity: The morpholino group's incorporation can significantly improve the binding affinity of the compound to specific biological targets, facilitating enhanced biological activity.

Furthermore, studies have shown that compounds of this nature can help in the effective delivery of genetic material, making them key players in the fields of gene therapy and biotechnology. As scientists continue to investigate their properties, we may uncover even more remarkable applications that could transform our understanding of cellular mechanisms and therapeutic approaches.

In conclusion, the exploration of morpholino(7,8,9,10-tetrahydro-6H-cycloheptabquinolin-11-yl)methanone exemplifies the exciting intersection of organic chemistry and molecular biology, highlighting the importance of innovative compounds in modern scientific research.

Synonyms
BRN 1143969
6H-Cyclohepta(b)quinoline, 7,8,9,10-tetrahydro-11-(morpholinocarbonyl)-
KETONE, MORPHOLINO(7,8,9,10-TETRAHYDRO-11-(6H-CYCLOHEPTA(b)QUINOLINYL))
7101-65-7
DTXSID90221242
DTXCID90143733