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Morpholinothiobenzophenone

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Identification
Molecular formula
C11H13NOS
CAS number
2516-44-5
IUPAC name
morpholino(phenyl)methanethione
State
State

At room temperature, Morpholinothiobenzophenone is typically in a solid state. It is commonly handled in its crystalline form for various applications in chemical synthesis and analysis.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
333.20
Boiling point (Kelvin)
606.35
General information
Molecular weight
221.31g/mol
Molar mass
221.3130g/mol
Density
1.2844g/cm3
Appearence

Morpholinothiobenzophenone typically appears as a solid crystalline substance. It often exhibits a light yellow to beige color due to its aromatic structure and is known for its characteristic odor associated with organic thioketones.

Comment on solubility

Solubility of Morpholino(phenyl)methanethione

Morpholino(phenyl)methanethione, with its complex structure, presents an intriguing solubility profile. Understanding the solubility of this compound can be quite essential for its applications in various fields. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of morpholino(phenyl)methanethione can vary significantly based on the choice of solvent. In polar solvents, the compound may show enhanced solubility due to interactions with solvent molecules.
  • Temperature Effects: Generally, solubility tends to increase with rising temperature. Therefore, heating the solvent may help dissolve morpholino(phenyl)methanethione more efficiently.
  • Hydrophobic Effects: The presence of phenyl groups may impart some hydrophobic character to the compound, potentially reducing its solubility in water. It’s likely to be more soluble in organic solvents such as ethanol, acetone, or dichloromethane.
  • pH Influence: Changes in pH may also affect the ionization state of morpholino groups, further influencing its solubility. Testing in various pH environments can help determine the optimal conditions for solubility.

In conclusion, the solubility of morpholino(phenyl)methanethione is a multifaceted attribute that hinges on a variety of factors including solvent type, temperature, and environmental conditions. As reflected in its chemical properties, optimal solubility conditions should be explored to enhance its utility in practical applications.

Interesting facts

Interesting Facts about Morpholino(phenyl)methanethione

Morpholino(phenyl)methanethione is an intriguing compound known for its unique molecular structure and a wide range of applications in the chemical and pharmaceutical industries. Below are some fascinating aspects of this compound:

  • Versatile Applications: This compound is often utilized in the synthesis of various pharmaceuticals and agrochemicals, demonstrating its importance in medicinal chemistry.
  • Distinct Functional Groups: The morpholino group is recognized for its ability to improve solubility and bioavailability of compounds, while the phenyl moiety contributes to the stability and reactivity of the molecule.
  • Research Significance: Morpholino(phenyl)methanethione serves as a valuable building block in organic synthesis, allowing chemists to design complex molecular architectures.
  • Potential for Drug Development: Due to its intriguing biological activities and structural characteristics, researchers are increasingly investigating its potential in the development of new therapeutic agents.
  • Sustainability: The search for more sustainable synthetic routes has highlighted compounds like morpholino(phenyl)methanethione as subjects of interest, emphasizing the need for environmentally friendly production methods.

As a chemistry student, exploring compounds such as morpholino(phenyl)methanethione opens doors to understanding the intricate relationships between structure and functionality in organic molecules. Engaging in this area of study not only broadens one’s knowledge of synthetic strategies but also fosters the innovation necessary for advancing drug discovery.

In the words of a renowned chemist, “The beauty of chemistry lies in the endless possibilities one can create from a single compound.” This perfectly encapsulates the journey and exploration that compounds like morpholino(phenyl)methanethione offer the scientific community.

Synonyms
MORPHOLINE, 4-(THIOBENZOYL)-
2032-36-2
4-(Thiobenzoyl)morpholine
Morpholinylthiobenzamide
Thiobenzomorpholide
Thiobenzoylmorpholine
Morpholine, 4-(phenylthioxomethyl)-
4-thiobenzoylmorpholine
NSC 406657
BRN 0148024
4-(Phenylthioxomethyl)morpholine
AI3-04872
A6178K128R
NSC-406657
N-THIOBENZOYLMORPHOLINE
DTXSID30174208
4-(THIOBENZOYL)-MORPHOLINE
4-27-00-00281 (Beilstein Handbook Reference)
4-MORPHOLINYLPHENYLMETHANETHIONE
4-(PHENYLTHIOCARBONYL)MORPHOLINE
DTXCID0096699
653-546-2
morpholin-4-yl(phenyl)methanethione
morpholino(phenyl)methanethione
4-Benzothioylmorpholine
NSC406657
4-Benzothioylmorpholine #
Morpholine, 4-thiobenzoyl-
TimTec1_004985
SCHEMBL9180076
CHEMBL2262740
UNII-A6178K128R
AEKJTLISCSMKLR-UHFFFAOYSA-
AEKJTLISCSMKLR-UHFFFAOYSA-N
morpholin-4-yl-phenylmethanethione
HMS1548C13
BDBM50487504
CCG-49621
STK795377
AKOS000353160
EU-0017641
AF-615/00108022
SR-01000639067-1
InChI=1/C11H13NOS/c14-11(10-4-2-1-3-5-10)12-6-8-13-9-7-12/h1-5H,6-9H2