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Morpholino(phenyl)methanone

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Identification
Molecular formula
C11H13NO2
CAS number
26521-82-4
IUPAC name
morpholino(phenyl)methanone
State
State

At room temperature, morpholino(phenyl)methanone is typically in a solid state. It is commonly encountered as a powder.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.10
Boiling point (Celsius)
305.50
Boiling point (Kelvin)
578.60
General information
Molecular weight
193.22g/mol
Molar mass
193.2220g/mol
Density
1.1823g/cm3
Appearence

Morpholino(phenyl)methanone typically appears as a crystalline powder. Its color ranges from off-white to a pale yellow.

Comment on solubility

Solubility of Morpholino(phenyl)methanone

Morpholino(phenyl)methanone, with its unique structure, presents variable solubility characteristics. Understanding its solubility is essential for applications in pharmaceuticals and chemical research. Here are some key aspects to consider:

  • Polar and Non-Polar Interaction: Morpholino(phenyl)methanone features both polar moieties due to the morpholine ring and non-polar characteristics from the phenyl group. This dual nature can lead to interesting solubility behavior.
  • Common Solvents: It typically shows better solubility in polar aprotic solvents such as dimethyl sulfoxide (DMSO) or acetonitrile compared to water.
  • Hydrophobic Effects: The phenyl group contributes to hydrophobic interactions, potentially reducing solubility in aqueous environments.
  • pH Dependency: The presence of nitrogen atoms in the morpholine ring may make the compound sensitive to pH, influencing its solubility in different buffer systems.

In summary, the solubility of morpholino(phenyl)methanone is significantly influenced by both solvent choice and environmental conditions. Knowing these factors can aid in maximizing its use in various chemical applications.

Interesting facts

Interesting Facts about Morpholino(phenyl)methanone

Morpholino(phenyl)methanone is a fascinating compound that belongs to the class of ketones, featuring a unique structure that combines the morpholine and phenyl groups. Below are some intriguing aspects of this compound:

  • Versatile Applications: This compound serves as a versatile intermediate in organic synthesis, often utilized in the development of pharmaceuticals and agrochemicals.
  • Functional Modifications: The morpholino group confers unique properties, making it valuable in the design of biologically active molecules.
  • Research Significance: Morpholino derivatives are often studied for their potential in medicinal chemistry, particularly in the context of targeting RNA for gene regulation.
  • Physical Properties: While the specifics of its physical and chemical properties are essential for practical applications, the structural characteristics alone provide a rich ground for research and exploration.
  • Chemical Behavior: The presence of the carbonyl group as part of the ketone structure makes it reactive in various chemical reactions, such as nucleophilic addition.

Overall, morpholino(phenyl)methanone exemplifies how simple structural modifications in organic compounds can lead to diverse functionalities and applications in science. As research continues to explore this compound, it may play a critical role in innovative developments in chemistry and pharmacology.

Synonyms
4-Benzoylmorpholine
1468-28-6
N-Benzoylmorpholine
Morpholine, 4-benzoyl-
MORPHOLINE, N-BENZOYL-
J8WEF5G9W6
BENZOIC MORPHOLIDE
NSC-3129
4-morpholinylphenylMethanone
DTXSID7074533
DTXCID0034778
morpholino(phenyl)methanone
Benzomorpholide
morpholin-4-yl(phenyl)methanone
Benzoic acid, morpholide
MFCD00188446
N-Benzoyl morpholine
4-Benzoyl morpholine
NSC 3129
BRN 0148023
morpholin-4-yl-phenylmethanone
AI3-03344
NSC3129
Maybridge1_007854
UNII-J8WEF5G9W6
Cambridge id 5116372
WLN: T6N DOTJ AVR
4-27-00-00280 (Beilstein Handbook Reference)
SCHEMBL946143
HMS563M22
FLCWYEUDIOQXEB-UHFFFAOYSA-N
STK414043
XH1090
AKOS000265465
GS-6389
PB40737
SDCCGMLS-0064617.P001
SY083783
DB-063680
CS-0051030
F13677
Z31721234