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IRL752

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Identification
Molecular formula
C22H31IN2O
CAS number
1524878-20-6
IUPAC name
N-[1-[(4-iodophenyl)methyl]-4-piperidyl]-3-isopropoxy-N-methyl-pyridin-2-amine
State
State

At room temperature, IRL752 is in a solid state. It is generally stable and does not readily decompose under standard conditions of temperature and pressure. The compound may require suitable handling to avoid exposure to moisture and other reactive substances.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
617.00
Boiling point (Kelvin)
890.15
General information
Molecular weight
488.40g/mol
Molar mass
488.3200g/mol
Density
1.4950g/cm3
Appearence

IRL752 typically appears as a crystalline powder. The compound's appearance may vary slightly depending on the degree of purification and the specific form such as salt or free base, but generally, it presents as a solid with a uniform texture and color, ranging from white to off-white.

Comment on solubility

Solubility Characteristics of N-[1-[(4-iodophenyl)methyl]-4-piperidyl]-3-isopropoxy-N-methyl-pyridin-2-amine

The solubility of N-[1-[(4-iodophenyl)methyl]-4-piperidyl]-3-isopropoxy-N-methyl-pyridin-2-amine (C22H31IN2O) is an intriguing aspect of its chemical nature. This compound, with its complex structure, exhibits solubility properties that can be influenced by several factors:

  • Polarity: The presence of the isopropoxy and pyridin-2-amine functional groups suggests that the compound may exhibit moderate polarity, which could enhance its solubility in polar organic solvents.
  • Hydrogen Bonding: The NH groups in the piperidine and pyridine rings may encourage hydrogen bonding, potentially improving solubility in protic solvents like ethanol and methanol.
  • Interactions with Iodine: The 4-iodophenyl substituent can influence interactions with solvents, possibly increasing solubility in halogen-compatible solvents due to dipole interactions.
  • Temperature Dependency: Like many organic compounds, solubility may vary with temperature; therefore, examining its solubility at different temperatures could yield interesting results.

In summary, the solubility of this compound is not only determined by its structural features but is also greatly affected by external conditions and the specific solvent used. Understanding its solubility can aid in predicting its behavior in various chemical environments.

Interesting facts

Interesting Facts about N-[1-[(4-iodophenyl)methyl]-4-piperidyl]-3-isopropoxy-N-methyl-pyridin-2-amine

N-[1-[(4-iodophenyl)methyl]-4-piperidyl]-3-isopropoxy-N-methyl-pyridin-2-amine is a compound that exemplifies the fascinating intersection of organic chemistry and medicinal applications. Here are some intriguing aspects to consider:

  • Pharmacological Potential: This compound is known to exhibit significant biological activity, particularly in the realm of pharmacology. Its structural features make it a candidate for development as an pharmacological agent.
  • Iodine Involvement: The presence of an iodine atom in the compound is particularly noteworthy. Iodinated compounds often show enhanced biological activity or imaging capabilities, making them valuable in medicinal chemistry.
  • Piperidine Ring: The piperidine moiety in this structure serves as a versatile scaffold in drug discovery. It can modify the lipophilicity and binding affinity of the compound when interacting with biological targets.
  • Synthetic Methodologies: The synthesis of this compound involves multiple steps of organic reaction techniques, which can include halogenation, alkylation, and nucleophilic substitutions. Each of these steps showcases the rich chemistry behind complex organic molecules.
  • Significance of Aromaticity: The aromatic phenyl group improves the stability and reactivity of the overall compound. Aromatic systems are a staple in medicinal chemistry, contributing to the specific interactions of drug candidates with their targets.

As a compound with a complex structure, N-[1-[(4-iodophenyl)methyl]-4-piperidyl]-3-isopropoxy-N-methyl-pyridin-2-amine presents numerous avenues for investigation. Considered as a potential therapeutic agent, its exploration could lead to significant advancements in drug development and pharmaceutical sciences.

Synonyms
RBI257
RBI 257
CHEMBL4096543
N-[1-[(4-iodophenyl)methyl]piperidin-4-yl]-N-methyl-3-propan-2-yloxypyridin-2-amine
N-[1-[(4-Iodophenyl)methyl]-4-piperidinyl]-N-methyl-3-(1-methylethoxy)-2-pyridinamine
194038-94-3
RBI-257
N-(1-((4-iodophenyl)methyl)piperidin-4-yl)-N-methyl-3-propan-2-yloxypyridin-2-amine
GTPL981
BDBM50257034
NS00017950
Q27088519
1-(4-iodobenzyl)-4-(N-(3-isopropoxy-2-pyridinyl)-N-methyl)aminopiperidine