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N-(1-adamantyl)formamide

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Identification
Molecular formula
C11H17NO
CAS number
702-71-2
IUPAC name
N-(1-adamantyl)formamide
State
State

At room temperature, N-(1-adamantyl)formamide is a solid. Its structure is non-linear due to the bulky adamantane group, and it is relatively stable under standard conditions.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
179.27g/mol
Molar mass
179.2710g/mol
Density
1.0908g/cm3
Appearence

N-(1-adamantyl)formamide is a colorless to pale yellow crystalline solid. It is characterized by its crystalline nature and can appear as slightly waxy due to the adamantane core structure.

Comment on solubility

Solubility of N-(1-adamantyl)formamide

N-(1-adamantyl)formamide, with the chemical formula C11H15NO, displays interesting solubility characteristics that make it notable among chemical compounds. This substance is primarily a polar molecule due to the presence of the amide functional group, which contributes to its solubility in various solvents.

Key Solubility Insights:

  • Polar Solvents: N-(1-adamantyl)formamide is soluble in polar solvents like water and ethanol, owing to its polar nature.
  • Non-Polar Solvents: The bulky adamantyl group lends some non-polar character, potentially allowing for limited solubility in non-polar organic solvents.
  • Solubility Variability: The solubility can vary significantly depending on temperature and the presence of other solutes in the solution.

As a result, researchers often find it helpful to conduct preliminary solubility tests in different solvents to determine the most effective solvent for their applications. In conclusion, the solubility of N-(1-adamantyl)formamide is a balance between its polar and non-polar characteristics, making it a versatile compound in various chemical contexts.

Interesting facts

Interesting Facts About N-(1-adamantyl)formamide

N-(1-adamantyl)formamide is a fascinating compound that integrates the unique structure of adamantane, a polycyclic hydrocarbon well-known for its stability and distinctive cage-like shape. Here are some intriguing aspects of this compound:

  • Versatile Chemical Interactions: The presence of both the adamantyl group and the formamide functionality allows this compound to engage in a variety of chemical reactions, making it a valuable building block in organic synthesis.
  • Therapeutic Potential: Research has suggested that derivatives of formamide can exhibit biological activity, including antimicrobial and anti-inflammatory properties. The inclusion of the adamantyl moiety could enhance these pharmacological effects.
  • Influence on Molecular Stability: The adamantyl group contributes to the overall stability of the compound. This feature is essential for maintaining its functional integrity during various chemical processes.
  • Unique Physical Properties: Compounds with the adamantane structure often display interesting behavior in terms of their physical properties, such as thermal stability and solubility, which can affect their application in materials science and pharmaceuticals.

As quoted in the literature, “The unique architecture of adamantane derivatives opens up numerous avenues for exploration in medicinal chemistry.” This sentiment reflects the ongoing research and interest surrounding N-(1-adamantyl)formamide, paving the way for innovative applications in diverse fields.

In summary, N-(1-adamantyl)formamide stands out due to its intriguing combination of structural elements and potential applications. It exemplifies the broad scope of chemistry, where modifications of basic structures can lead to varied properties and uses in science and industry.

Synonyms
1-adamantylformamide
658-640-7
N-(1-Adamantyl)formamide
3405-48-9
FORMAMIDE, N-(1-ADAMANTYL)-
1-(Formylamino)adamantane
BRN 2209455
formylaminoadamantane
1-formamidoadamantane
SCHEMBL812583
Formamide, N-tricyclo(3.3.1.1(3,7))dec-1-yl-
DTXSID30187656
STL406639
AKOS003884886
AKOS006279875
Formamide, tricyclo[3.3.1.1]dec-1-yl-
N-tricyclo[3.3.1.1~3,7~]dec-1-ylformamide