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Raltegravir

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Identification
Molecular formula
C20H20FKN6O5
CAS number
518048-05-0
IUPAC name
N-[1-benzyl-2-(dimethylamino)-2-oxo-ethyl]-2-oxo-N'-[2-(2-pyridyl)ethyl]butanediamide
State
State

At room temperature, Raltegravir is in a solid state.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.00
Boiling point (Celsius)
760.00
Boiling point (Kelvin)
1 033.00
General information
Molecular weight
444.92g/mol
Molar mass
444.9240g/mol
Density
1.3000g/cm3
Appearence

Raltegravir is a white to off-white crystalline powder.

Comment on solubility

Solubility Profile of N-[1-benzyl-2-(dimethylamino)-2-oxo-ethyl]-2-oxo-N'-[2-(2-pyridyl)ethyl]butanediamide

The solubility of N-[1-benzyl-2-(dimethylamino)-2-oxo-ethyl]-2-oxo-N'-[2-(2-pyridyl)ethyl]butanediamide (C20H20FKN6O5) can be quite complex due to its intricate structure and functional groups. A few key points regarding its solubility are:

  • Polarity: The presence of amide and ketone groups suggests potential for hydrogen bonding, which typically increases solubility in polar solvents.
  • Hydrophobic Characteristics: The benzyl group can impart some hydrophobic character to the compound, which may limit its solubility in water.
  • Solvent Compatibility: It is likely more soluble in organic solvents such as ethyl acetate or dimethyl sulfoxide (DMSO) rather than in purely aqueous solutions.
  • pH Dependency: The solubility may also vary with pH, as the protonation state of the amine may influence solubility in different environments.

In conclusion, understanding the solubility behavior of this compound requires consideration of both its hydrophilic and hydrophobic elements. As a result, when assessing its solubility, one should consult experimental data and consider various solvent systems to determine optimal conditions for dissolution.

Interesting facts

Interesting Facts about N-[1-benzyl-2-(dimethylamino)-2-oxo-ethyl]-2-oxo-N'-[2-(2-pyridyl)ethyl]butanediamide

This fascinating compound is a member of the class of chemical compounds known for their versatile applications in medicinal chemistry and organic synthesis. It stands out due to the following characteristics:

  • Unique Structure: The compound features a complex structure with multiple functional groups such as amides and keto groups, making it interesting for the study of its reactivity and properties.
  • Pharmacological Potential: The presence of a dimethylamino group and a pyridine moiety suggests potential biological activity. Many compounds with similar structures exhibit notable pharmacological effects, including antitumor and antiviral properties.
  • Complex Synthesis: The synthesis of this compound requires advanced synthetic techniques, often involving multiple reaction steps and careful control of conditions, providing an excellent learning opportunity for chemistry students.
  • Interdisciplinary Connections: This compound exemplifies the intersection of organic chemistry with fields such as medicinal chemistry and biochemistry, showcasing how structural modifications can influence biological activity.

As a chemistry student or scientist, exploring compounds like this one can deepen your understanding of structure-activity relationships and inspire innovative research directions. Remember, each compound tells a story of its own, from its synthesis to its potential applications in medicine!

Synonyms
SCHEMBL4315317
PD042991