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N-(1-benzyl-3,3,3-trifluoro-2-oxo-propyl)acetamide

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Identification
Molecular formula
C12H12F3NO2
CAS number
4318-56-3
IUPAC name
N-(1-benzyl-3,3,3-trifluoro-2-oxo-propyl)acetamide
State
State

At room temperature, this compound exists in a solid state.

Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
259.20
Boiling point (Kelvin)
532.35
General information
Molecular weight
255.24g/mol
Molar mass
255.2390g/mol
Density
1.2400g/cm3
Appearence

The compound is a white to off-white solid with a crystalline appearance.

Comment on solubility

Solubility of N-(1-benzyl-3,3,3-trifluoro-2-oxo-propyl)acetamide

N-(1-benzyl-3,3,3-trifluoro-2-oxo-propyl)acetamide (C12H12F3NO2) showcases notable characteristics regarding its solubility profile. Understanding its behavior in various solvents is crucial for its applications in chemical processes. Here are some key points:

  • Polar Solvents: This compound is expected to show good solubility in polar solvents such as water and alcohols due to the presence of the amide functional group that can form hydrogen bonds.
  • Non-Polar Solvents: In contrast, its solubility in non-polar solvents, like hexane or benzene, may be significantly lower owing to the hydrophobic nature imparted by the benzyl and trifluoroalkyl moieties.
  • Temperature Influence: The solubility can also vary with temperature, generally increasing with temperature for organic compounds, facilitating more effective reactions in heated environments.
  • Concentration Factors: At higher concentrations, precipitation might occur if the solvent capacity is surpassed, reflecting a complex interplay in solubility dynamics.

In summary, the solubility of N-(1-benzyl-3,3,3-trifluoro-2-oxo-propyl)acetamide is greatly influenced by both its molecular structure and the nature of the solvent. Its potential applications will often hinge on this solubility behavior, making it a critical aspect to consider in laboratory and industrial scenarios.

Interesting facts

Interesting Facts about N-(1-benzyl-3,3,3-trifluoro-2-oxo-propyl)acetamide

N-(1-benzyl-3,3,3-trifluoro-2-oxo-propyl)acetamide is a unique compound that showcases fascinating chemical properties and potential applications.

Chemical Structure

This compound features a complex structure characterized by:

  • Trifluoromethyl Group: The presence of three fluorine atoms significantly alters the compound's reactivity and polarity, making it a subject of interest in synthetic organic chemistry.
  • Benzyl Group: The benzyl functional group contributes to the overall stability and hydrophobic characteristics, which can influence solubility in organic solvents.
  • Acetamide Linkage: The acetamide functional group can participate in hydrogen bonding, which may enhance interaction with biological targets, making it a candidate for drug development.

Potential Applications

This compound may have significant implications across various fields:

  • Pharmaceuticals: Due to its unique structure, it may serve as a lead compound in drug discovery, particularly in areas focused on anti-inflammatory and antitumor activities.
  • Materials Science: Its chemical properties might allow it to be used in creating specialized materials, such as coatings that demand high thermal stability and chemical resistance.

Research Insights

Recent studies suggest that compounds with trifluoromethyl groups can enhance metabolic stability and minimize off-target effects in biological systems. Furthermore, as researchers explore the interactions between such compounds and biological molecules, there is great potential for discovering new therapeutic avenues.

In conclusion, N-(1-benzyl-3,3,3-trifluoro-2-oxo-propyl)acetamide is not just a compound of chemical interest, but also a promising candidate in the realms of medicine and materials science. Its unique structural features warrant further investigation and could lead to groundbreaking discoveries.

Synonyms
128550-40-3
Acetamide, N-[3,3,3-trifluoro-2-oxo-1-(phenylmethyl)propyl]-
N-(4,4,4-trifluoro-3-oxo-1-phenylbutan-2-yl)acetamide
SCHEMBL13967231
DTXSID60274301
JTIIYPHJIDENCW-UHFFFAOYSA-N
N1,N5,N10,N14-tetra-tert-butoxycarbonyl-1,5,10,14,18-pentaazaoctadecane
PD037916