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Isopropoxyphenyl Piperidinyl Pyridin Amine

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Identification
Molecular formula
C20H29N3O
CAS number
1625-40-5
IUPAC name
N-(1-benzyl-4-piperidyl)-3-isopropoxy-N-methyl-pyridin-2-amine
State
State

This compound is typically a solid at room temperature, and it is usually handled as a powder.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
323.45g/mol
Molar mass
323.4480g/mol
Density
1.0200g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. It may have a slight odor depending on the specific formulation and impurities.

Comment on solubility

Solubility Characteristics of N-(1-benzyl-4-piperidyl)-3-isopropoxy-N-methyl-pyridin-2-amine (C20H29N3O)

The solubility of N-(1-benzyl-4-piperidyl)-3-isopropoxy-N-methyl-pyridin-2-amine is influenced by several factors due to its complex molecular structure. Here's a breakdown of its solubility properties:

  • Polarity: The presence of polar functional groups, such as the isopropoxy and pyridinamine moieties, suggests that the compound may exhibit moderate to good solubility in polar solvents like water and alcohols.
  • Hydrophobic Interactions: The benzyl and piperidine components contribute to hydrophobic interactions, which could reduce solubility in strictly polar solvents.
  • Solvent Systems: It is likely to be more soluble in organic solvents like methanol, ethanol, and dimethyl sulfoxide (DMSO) due to the combination of its polar and nonpolar features.
  • Temperature Dependence: Solubility may increase with temperature, which is a common behavior for many organic compounds.

In conclusion, while N-(1-benzyl-4-piperidyl)-3-isopropoxy-N-methyl-pyridin-2-amine shows potential for solubility in both polar and nonpolar environments, the specific solubility can vary significantly based on the solvent's nature, temperature, and concentration. Researchers aiming to utilize this compound should conduct empirical solubility tests in various solvents to determine optimal conditions for their specific applications.

Interesting facts

Interesting Facts about N-(1-benzyl-4-piperidyl)-3-isopropoxy-N-methyl-pyridin-2-amine

N-(1-benzyl-4-piperidyl)-3-isopropoxy-N-methyl-pyridin-2-amine is a fascinating compound with several intriguing features that make it noteworthy in the field of chemistry:

  • Pharmacological Potential: This compound belongs to a class of molecules that often exhibit promising pharmacological properties, particularly in the field of neuroscience and psychiatry. It's believed to interact with various neurotransmitter systems, potentially offering therapeutic effects.
  • Molecular Structure: The structure of this compound includes a complex arrangement of piperidine and pyridine rings, which contribute to its biological activity. The presence of both a benzyl group and isopropoxy group introduces steric hindrance, which can affect the compound's interactions with its biological targets.
  • Research Applications: Compounds like N-(1-benzyl-4-piperidyl)-3-isopropoxy-N-methyl-pyridin-2-amine might be the subject of ongoing research for their potential use in treating conditions like anxiety, depression, or even neurodegenerative diseases.
  • Synthesis and Stability: The synthetic pathways to create this compound can be complex, often involving multiple steps. Chemists are particularly interested in optimizing the synthesis to enhance yield and reduce potential side reactions.
  • Chemical Diversity: This compound exemplifies the vast diversity in chemical structures available in organic chemistry. The variations in side groups (like the isopropoxy and benzyl) dramatically alter the properties and behaviors of the molecules, leading to extensive applications.

As we continue to explore the properties and applications of this compound, it stands out as a prime candidate for future **research** and **development** in medicinal chemistry. The interplay of its unique structural features with biological systems is a testament to the complex and wonderful world of chemical compounds.

Synonyms
U 101958
U-101958
170856-57-2
U101958
DTXSID40168956
3-Isopropoxy-N-methyl-N-(1-(phenylmethyl)-4-piperidinyl)-2-pyridinylamine
N-methyl-N-[1-(phenylmethyl)piperidin-4-yl]-3-propan-2-yloxypyridin-2-amine
PNU 101958
CHEMBL64119
N-methyl-N-(1-(phenylmethyl)piperidin-4-yl)-3-propan-2-yloxypyridin-2-amine
NCGC00016072-01
Lopac-U-115
Lopac0_001276
GTPL5781
SCHEMBL8406537
CHEMBL1179189
DTXCID4091447
BDBM50071208
CCG-205349
SDCCGSBI-0051242.P002
NCGC00016072-02
NCGC00016072-03
NCGC00016072-05
NCGC00162387-01
Q27089043
(1-Benzyl-piperidin-4-yl)-(3-isopropoxy-pyridin-2-yl)-methyl-amine; compound with (Z)-but-2-enedioic acid