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N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide

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Identification
Molecular formula
C16H24N2O4S
IUPAC name
N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide
State
State

At room temperature, this compound is typically a solid, given its high melting point. It likely exists as crystalline or powdered form, stable under standard conditions.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
480.00
Boiling point (Kelvin)
753.15
General information
Molecular weight
354.46g/mol
Molar mass
354.4550g/mol
Density
1.2500g/cm3
Appearence

This compound is expected to be a crystalline solid. The specific color, if crystallized, would depend on the specific conditions of synthesis and the presence of any impurities. Typically, such compounds are white to off-white in color.

Comment on solubility

Solubility of N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide

The solubility of this compound, C16H24N2O4S, is influenced by various structural characteristics and interactions with solvents. Here are important factors to consider:

  • Polarity: The presence of the -O (methoxy) and -S (sulfonyl) functional groups contributes to the overall polarity of the molecule, enhancing solubility in polar solvents.
  • Hydrogen Bonding: The capability of the compound to participate in hydrogen bonding due to the nitrogen and oxygen atoms can significantly improve solubility in polar solvents such as water.
  • Hydrophobic Regions: However, the ethyl groups attached to the structure introduce hydrophobic character, which may hinder solubility in some polar solvents.

In general, one might observe that:

  • Solubility tends to be greater in organic solvents such as ethanol or DMSO due to their ability to interact with the hydrophobic regions of the molecule.
  • Conversely, limited solubility may be evident in highly polar solvents, which may not sufficiently compensate for the hydrophobic parts of the molecule.

Thus, to sum up, the solubility of N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide is a complex interplay of its structural features. As the saying goes, "solubility is the key to potential applications," making understanding its solubility a vital pursuit in chemical research.

Interesting facts

Interesting Facts about N-[(1-Ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide

This fascinating compound, with its complex structure, offers a rich area of study for both scientists and chemistry students alike. Here are some intriguing aspects:

  • Synthetic Relevance: The compound belongs to a class of molecules often explored in medicinal chemistry for their potential pharmacological properties. Understanding its synthesis can lead to insights on developing new therapeutic agents.
  • Structural Insights: The presence of the ethoxy and methoxy groups in the molecular structure suggests a role in enhancing bioactivity and modulating interaction with biological targets, making it a point of interest in drug development.
  • Biological Potential: Compounds containing sulfonyl groups are known for their ability to inhibit various enzymes and receptor interactions. Researching this compound could reveal its effects on specific biological pathways.
  • Amide Bond: The amide functional group contributes to the stability of the molecule and influences its solubility and reactivity, key factors in understanding how the compound behaves in biological systems.
  • Understanding Substituted Aromatic Compounds: This compound's aromatic system makes it a model for studying π-π stacking interactions, which are crucial in many biochemical processes. It can serve as a classroom example for students learning about molecular interactions.

As a compound that bridges organics with potential medicinal applications, N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide invites deep exploration. The intricate balance of structure and function exemplified here highlights the beauty of chemistry and its implications in pharmaceuticals.

As aspiring chemists delve into such compounds, it reinforces the notion that "every molecule tells a story," leading to an understanding that goes beyond mere formulas and into the realm of real-world applications.

Synonyms
Sultopride
53583-79-2
Barnetil
Topral
LIN 1418
Sultopridum [INN-Latin]
Sultopridum
Sultroprida
Sultopride [INN:DCF]
Sultroprida [INN-Spanish]
(+/-)-Sultopride
Sultoprida
LIN-1418
EINECS 258-641-9
AA0G3TW31W
Sultopride (INN)
BRN 0494772
SULTOPRIDE [MI]
SULTOPRIDE [INN]
N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide
SULTOPRIDE [WHO-DD]
Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-
CHEBI:9356
DTXSID9023627
5-22-08-00103 (Beilstein Handbook Reference)
Sultopridum (INN-Latin)
N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide
o-ANISAMIDE, N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-5-(ETHYLSULFONYL)-
Sultroprida (INN-Spanish)
N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide
(+/-)-N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-5-(ETHYLSULFONYL)-2-METHOXYBENZAMIDE
N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-5-(ETHYLSULFONYL)-2-METHOXYBENZAMIDE
NCGC00185771-01
UNII-AA0G3TW31W
N-((1-ethylpyrrolidin-2-yl)methyl)-5-ethylsulfonyl-2-methoxy-benzamide
N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
SCHEMBL149197
CHEMBL277945
DTXCID903627
BDBM86720
N05AL02
KXB00443
NSC_5357
PDSP1_001575
PDSP2_001559
AKOS024255726
DB13273
KS-5337
HY-42849
CAS_53583-79-2
DB-071706
CS-0040602
NS00009087
D08549
SBI-0654155.0001
EN300-18563734
L001065
Q4445779
5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide
N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-(methyloxy)benzamide
258-641-9