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N-(1-fluoro-9H-fluoren-2-yl)acetamide

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Identification
Molecular formula
C15H12FNO
CAS number
446-62-2
IUPAC name
N-(1-fluoro-9H-fluoren-2-yl)acetamide
State
State

At room temperature, N-(1-fluoro-9H-fluoren-2-yl)acetamide is a solid, which is typical for many organic compounds with relatively higher molecular weights and aromatic features.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
346.00
Boiling point (Kelvin)
619.15
General information
Molecular weight
227.26g/mol
Molar mass
227.2380g/mol
Density
1.3010g/cm3
Appearence

N-(1-fluoro-9H-fluoren-2-yl)acetamide typically appears as a white to off-white crystalline solid. The compound's appearance can vary slightly based on purity and specific manufacturing processes.

Comment on solubility

Solubility of N-(1-fluoro-9H-fluoren-2-yl)acetamide

N-(1-fluoro-9H-fluoren-2-yl)acetamide is a compound with intriguing solubility characteristics influenced by its molecular structure. Understanding the solubility of this compound can be crucial for various applications in the chemical and pharmaceutical industries. Here are some key points regarding its solubility:

  • Polarity: The presence of both the acetamide functional group and the fluoro substituent contributes to the overall polarity of the molecule. This can lead to enhanced solubility in polar solvents.
  • Solvent Interaction: N-(1-fluoro-9H-fluoren-2-yl)acetamide is likely to exhibit good solubility in solvents such as water, alcohols (like ethanol), and other polar protic solvents due to hydrogen bonding capabilities.
  • Temperature Dependence: The solubility of organic compounds often increases with temperature. Thus, warming the solvent may enhance the dissolution of this acetamide.
  • Application in Reactions: High solubility in polar solvents makes it an excellent candidate for mediation in reactive processes, allowing for better interaction with other chemical species.

In summary, the solubility of N-(1-fluoro-9H-fluoren-2-yl)acetamide is dictated by its structural features, particularly its functional groups, making it versatile in various solvent environments. The intricate balance of polarity and temperature plays a vital role in its dissolving behavior.

Interesting facts

Interesting Facts about N-(1-Fluoro-9H-fluoren-2-yl)acetamide

N-(1-Fluoro-9H-fluoren-2-yl)acetamide is a fascinating compound that showcases both the diversity of functional groups in organic chemistry and the utility of fluorinated derivatives in various applications. Here are some intriguing insights:

  • Fluorine Chemistry: The presence of fluorine in this compound enhances its reactivity and stability. Fluorine's electronegativity can influence the electronic properties of the molecule, making it an important element in medicinal chemistry.
  • Fluorenyl Moiety: The structural backbone of fluorenes is notable for its unique fused ring system, which imparts interesting photophysical properties. This makes fluorenes valuable in optoelectronic materials and as phosphorescent agents.
  • Potential Applications: Compounds like N-(1-Fluoro-9H-fluoren-2-yl)acetamide could be explored in drug design and development. Fluorinated compounds often display altered biological activity compared to their non-fluorinated counterparts.
  • Research Interest: The reactivity patterns of acetamide derivatives, particularly when fluorine is involved, have been the subject of extensive research due to their ability to form varied intermediates that are essential in synthesizing complex molecules.

As noted by chemists, “Understanding the role of fluorine in organic compounds is key to unlocking new pathways in synthetic chemistry.” The study of N-(1-Fluoro-9H-fluoren-2-yl)acetamide, therefore, not only highlights the intricacies of organic synthesis but also opens doors to innovative therapeutic agents and novel materials.

Synonyms
1-Fluoro-2-faa
1-Fluoro-2-acetylaminofluorene
2824-10-4
ACETAMIDE, N-(1-FLUOROFLUOREN-2-YL)-
N-(1-Fluorofluoren-2-yl)acetamide
Acetamide, N-(1-fluoro-9H-fluoren-2-yl)-
U48GC3MS6L
N-(1-fluoro-9H-fluoren-2-yl)acetamide
NSC-405795
NSC405795
NSC 405795
BRN 2811019
UNII-U48GC3MS6L
CHEMBL83541
DTXSID80182494
WLN: L B656 HHJ EMV1 FF