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Laurocapram

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Identification
Molecular formula
C15H31NO2
CAS number
59227-89-3
IUPAC name
N-(1-hydroxy-1-methyl-ethyl)dodecanamide
State
State

At room temperature, it is typically a solid, specifically a white crystalline solid.

Melting point (Celsius)
29.00
Melting point (Kelvin)
302.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
227.42g/mol
Molar mass
227.3960g/mol
Density
0.9006g/cm3
Appearence

Laurocapram, commonly known as Azone, is a white crystalline solid. It is often in the form of a white powder and is noted for its ability to enhance the penetration of substances through the skin, which is why it is frequently used in topical pharmaceutical formulations.

Comment on solubility

Solubility of N-(1-hydroxy-1-methyl-ethyl)dodecanamide

N-(1-hydroxy-1-methyl-ethyl)dodecanamide, often referred to simply as a long-chain amide, exhibits unique solubility properties that are influenced by its molecular structure.

Solubility Characteristics

This compound can be analyzed for solubility based on various solvents:

  • Water: Due to the presence of the hydroxyl group, N-(1-hydroxy-1-methyl-ethyl)dodecanamide may have some degree of solubility in water, although it is likely limited due to the hydrophobic dodecane tail.
  • Organic Solvents: It tends to be more soluble in organic solvents like ethanol, methanol, and chloroform, which can solvate both the polar and non-polar regions of its structure.
  • Oil: Given its long hydrocarbon chain, it exhibits high solubility in oils, making it a suitable candidate for formulations requiring non-polar mixtures.

In practical applications, the solubility behavior can be summarized as follows:

  1. Moderately soluble in polar solvents.
  2. Highly soluble in non-polar solvents.
  3. Low solubility in water due to the balance between hydrophobic and hydrophilic interactions.

In the context of applications, this solubility profile makes N-(1-hydroxy-1-methyl-ethyl)dodecanamide useful in cosmetic formulations and surfactant applications, where the balance of solubility can impact efficacy and stability.

Interesting facts

Interesting Facts About N-(1-hydroxy-1-methyl-ethyl)dodecanamide

N-(1-hydroxy-1-methyl-ethyl)dodecanamide, a fascinating compound with diverse applications, presents a unique landscape for scientific exploration. Here are some intriguing insights into its properties and uses:

  • Versatile Use: This compound serves as a significant ingredient in various industries, including cosmetics, pharmaceuticals, and agriculture. Its versatility makes it an attractive option for formulators seeking effective materials.
  • Biological Significance: As an amide, it may exhibit biological properties that could influence its potential use in drug formulation. Studying such compounds can lead to the discovery of new therapies and biological mechanisms.
  • Surface Activity: Due to its long carbon chain and polar amine group, this compound can act as an effective surfactant, improving the emulsification of various substances. This ability is critical in formulating creams and lotions where stability is essential.
  • Hydrophilic and Hydrophobic Balance: Its structure allows for a balance between hydrophilic and hydrophobic properties, making it useful in creating emulsions and enhancing solubility in different solvents.

Research on N-(1-hydroxy-1-methyl-ethyl)dodecanamide can lead to advancements in sustainable practices, especially in formulations that require biodegradable options. As scientists continue to investigate its functionalities, the compound may reveal even more potential applications that could benefit numerous fields.

In the words of a prominent chemist, "The most profound discoveries often come from exploring the simplest of compounds." Indeed, N-(1-hydroxy-1-methyl-ethyl)dodecanamide exemplifies how humble beginnings can lead to extraordinary innovations.

Synonyms
lauric isopropanol amide
SCHEMBL2380630
JHBUNKKNHQVQFT-UHFFFAOYSA-N
NS00076963