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N-(1-hydroxy-9H-fluoren-2-yl)acetamide

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Identification
Molecular formula
C15H13NO2
CAS number
3964-45-2
IUPAC name
N-(1-hydroxy-9H-fluoren-2-yl)acetamide
State
State

At room temperature, N-(1-hydroxy-9H-fluoren-2-yl)acetamide exists in a solid state. It is usually available as crystalline powder.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
487.80
Boiling point (Kelvin)
760.95
General information
Molecular weight
225.25g/mol
Molar mass
225.2470g/mol
Density
1.2190g/cm3
Appearence

N-(1-hydroxy-9H-fluoren-2-yl)acetamide typically appears as an off-white to pale yellow crystalline powder. It may also exhibit a mild odor.

Comment on solubility

Solubility of N-(1-hydroxy-9H-fluoren-2-yl)acetamide

The solubility of N-(1-hydroxy-9H-fluoren-2-yl)acetamide can be influenced by various factors such as temperature, pH, and the presence of other solutes. Generally, this compound is expected to be soluble in organic solvents due to its hydrophobic fluorene structure. Here are some key points to consider regarding its solubility:

  • Polar solvents: While it may exhibit limited solubility in water due to the large non-polar fluorene moiety, it can engage in hydrogen bonding through the hydroxyl group, potentially allowing for some solubility at elevated temperatures.
  • Non-polar solvents: The compound is likely to demonstrate higher solubility in non-polar solvents such as chloroform or benzene, aligning with the principles of 'like dissolves like.'
  • pH Influence: The ionizable amide group may respond to changes in pH, possibly enhancing solubility in more alkaline or acidic mediums.

Understanding the solubility behavior of N-(1-hydroxy-9H-fluoren-2-yl)acetamide is essential for applications in fields such as pharmaceuticals and materials science, where solvent compatibility can dictate efficacy and performance.

Interesting facts

Exploring N-(1-hydroxy-9H-fluoren-2-yl)acetamide

N-(1-hydroxy-9H-fluoren-2-yl)acetamide is a fascinating compound that finds its place in the realm of organic chemistry due to its unique structural features and potential applications. Here are some intriguing facts about this compound:

  • Structural Significance: The compound contains a fluorenyl group, which contributes to its distinctive structure. This fused ring system is known for its interesting electronic properties, making it a point of interest for chemists.
  • Versatile Applications: Compounds like N-(1-hydroxy-9H-fluoren-2-yl)acetamide are often explored in the fields of medicinal chemistry. They may have potential applications in drug development or serve as intermediates in the synthesis of more complex molecules.
  • Hydroxyl Functionality: The presence of the hydroxyl group (–OH) in the structure increases the compound's reactivity. Hydroxyl groups can participate in hydrogen bonding, which can influence solubility and interactions with biological systems.
  • Research Interest: Given its unique features, this compound has garnered attention in various research studies, particularly those focusing on organic synthesis and the development of new materials.

In summary, N-(1-hydroxy-9H-fluoren-2-yl)acetamide stands out due to its structural uniqueness and the potential it holds for future applications in scientific research. As chemists continue to delve into the properties and reactions of this compound, it may lead to new discoveries and advancements in the field.

Synonyms
2784-86-3
1-Hydroxy-2-acetamidofluorene
1-Hydroxy-2-acetylaminofluorene
N-(1-hydroxy-9H-fluoren-2-yl)acetamide
1-Hydroxy-N-2-fluorenylacetamide
acetamide, N-(1-hydroxy-9H-fluoren-2-yl)-
N-(1-Hydroxy-2-fluorenyl)acetamide
ACETAMIDE, N-(1-HYDROXYFLUOREN-2-YL)-
N-(1-Hydroxy-9H-fluoren-2-yl)-acetamide
E69KV8M7W5
CHEBI:34090
NSC-40565
CCRIS 2766
NSC 40565
BRN 2738062
UNII-E69KV8M7W5
hydroxy-2-acetylaminofluorene
4-13-00-02236 (Beilstein Handbook Reference)
CHEMBL50511
DTXSID20182155
CAA78486
NSC40565
WLN: L B656 HHJ EMV1 FQ
N-(1-Hydroxyfluoren-2-yl)-acetamide
HYDROXY-2-ACETYLAMINOFLUORENE, 1-
1-HYDROXY-N-ACETYL-2-AMINOFLUORENE
Q27115803
InChI=1/C15H13NO2/c1-9(17)16-14-7-6-12-11-5-3-2-4-10(11)8-13(12)15(14)18/h2-7,18H,8H2,1H3,(H,16,17