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Ivermectin

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Identification
Molecular formula
C48H74O14
CAS number
70288-86-7
IUPAC name
N-[(1-isopropyl-4-methyl-3-bicyclo[3.1.0]hexanylidene)amino]pyridine-4-carboxamide
State
State

Ivermectin typically is in a solid state at room temperature.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
718.00
Boiling point (Kelvin)
991.15
General information
Molecular weight
875.10g/mol
Molar mass
875.1020g/mol
Density
1.2200g/cm3
Appearence

Ivermectin is a white crystalline powder. It is generally found in a solid state at standard room temperature and pressure.

Comment on solubility

Solubility Characteristics

The solubility of N-[(1-isopropyl-4-methyl-3-bicyclo[3.1.0]hexanylidene)amino]pyridine-4-carboxamide can be influenced by various factors including its molecular structure, polarity, and intermolecular interactions. Here are some key points to consider:

  • Polarity: Compounds with polar functional groups tend to exhibit higher solubility in polar solvents such as water. The presence of the pyridine ring and the carboxamide group in this compound suggests some degree of polarity, potentially enhancing its solubility in polar environments.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly affect solubility. The carboxamide moiety is capable of forming hydrogen bonds with water, which may increase the solubility.
  • Cycloalkane Structure: The bicyclo[3.1.0]hexane component may introduce steric hindrance, which could complicate solubility due to less favorable interactions with solvent molecules.
  • Solvent Effects: In organic solvents such as ethanol or acetone, solubility may differ greatly compared to aqueous solutions. Thus, testing in various solvents can provide a better perspective on solubility.

In conclusion, the solubility of N-[(1-isopropyl-4-methyl-3-bicyclo[3.1.0]hexanylidene)amino]pyridine-4-carboxamide is likely moderate-to-high in polar solvents due to its functional groups, although the bicyclic structure may limit this in certain cases. It would be prudent to conduct empirical tests to determine its exact solubility profile.

Interesting facts

Unique Insights into N-[(1-Isopropyl-4-methyl-3-bicyclo[3.1.0]hexanylidene)amino]pyridine-4-carboxamide

N-[(1-Isopropyl-4-methyl-3-bicyclo[3.1.0]hexanylidene)amino]pyridine-4-carboxamide, a complex chemical compound, offers fascinating insights into its structure and potential applications. This compound falls into the category of substituted pyridines, which are especially important in medicinal chemistry due to their diverse biological activities.

Key Characteristics

  • Substituted Pyridine Structure: The presence of the pyridine ring suggests potential pharmacological activities, making it suitable for various drug development processes.
  • Bicyclic Influence: The bicyclo structure contributes to steric effects that can influence reactivity and interaction with biological targets.
  • Isopropyl and Methyl Groups: These groups not only affect the compound's geometry but may also enhance lipophilicity, which is crucial for membrane permeability in biological systems.

According to chemists, compounds like N-[(1-isopropyl-4-methyl-3-bicyclo[3.1.0]hexanylidene)amino]pyridine-4-carboxamide can often exhibit selective receptor activity. This means they may target specific pathways within biological systems, potentially leading to lower side effects compared to non-selective drugs. "The precision in targeting is what defines modern medicinal chemistry," a notable scientist once said.

Applications and Considerations

The compound's unique structure could lead to several intriguing applications:

  • **Pharmaceutical Research:** It may serve as a lead compound for developing therapies related to neurological or inflammatory conditions.
  • **Agricultural Chemistry:** Its properties might find applications in creating effective pesticides or herbicides that are selective to pests while being safe for the ecosystem.
  • **Material Science:** Modifications to the compound could result in novel materials with unique thermal or mechanical properties.

Given its complexity, further research and exploration of N-[(1-isopropyl-4-methyl-3-bicyclo[3.1.0]hexanylidene)amino]pyridine-4-carboxamide are essential to unlock its full potential and understand its mechanisms of action in biological systems. As the field of chemistry advances, compounds like this will undoubtedly play a key role in future innovations.