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Fentanyl

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Identification
Molecular formula
C22H28N2O
CAS number
437-38-7
IUPAC name
N-[1-methyl-2-(1-piperidyl)ethyl]-N-phenyl-propanamide
State
State

At room temperature, fentanyl is most commonly found as a solid, especially when synthesized as a powder for medicinal manufacturing processes. However, it can also be found in transdermal patches for pain management, where it is dispersed in a gel or liquid medium.

Melting point (Celsius)
87.50
Melting point (Kelvin)
360.65
Boiling point (Celsius)
760.00
Boiling point (Kelvin)
1 033.15
General information
Molecular weight
336.47g/mol
Molar mass
336.4710g/mol
Density
1.1576g/cm3
Appearence

Fentanyl is typically encountered as a white or off-white powder. It can also be found in solution form for intravenous use. In some cases, it can appear in patch form, which is used for slow absorption in medical treatments.

Comment on solubility

Solubility of N-[1-methyl-2-(1-piperidyl)ethyl]-N-phenyl-propanamide

The solubility of N-[1-methyl-2-(1-piperidyl)ethyl]-N-phenyl-propanamide is an intriguing aspect of its chemical behavior. Understanding the solubility characteristics of this compound can provide insights into its potential applications and interactions. Here are some key points regarding its solubility:

  • Polarity: The presence of both hydrophobic (phenyl group) and hydrophilic (amide group) characteristics suggests that this compound may exhibit moderate solubility in various solvents.
  • Solvent Compatibility: Organic solvents such as ethanol and dimethyl sulfoxide (DMSO) may be effective for dissolving this compound, while it may have limited solubility in non-polar solvents.
  • Temperature Influence: As with many organic compounds, solubility may increase with temperature; higher temperatures may favor solubility in a range of solvents.
  • pH Dependence: The ionization of the amide functional group could suggest that solubility might vary with changes in pH, leading to either enhanced or diminished solubility in aqueous environments.

In summary, the solubility of N-[1-methyl-2-(1-piperidyl)ethyl]-N-phenyl-propanamide is influenced by multiple factors, including its molecular structure and environmental conditions. Thus, experiments to determine specific solubility metrics in various solvents would provide valuable information for practical applications.

Interesting facts

Interesting Facts about N-[1-methyl-2-(1-piperidyl)ethyl]-N-phenyl-propanamide

N-[1-methyl-2-(1-piperidyl)ethyl]-N-phenyl-propanamide, often known by its shorthand, is a unique compound that belongs to the class of amides. This chemical structure has garnered attention due to its intriguing properties and potential applications. Here are some noteworthy facts about this compound:

  • Pharmacological Potential: The compound is believed to exhibit interesting pharmacological properties, making it a candidate for further research in medicinal chemistry. It may have implications for the development of new therapeutic agents.
  • Piperidine Derivative: The presence of the piperidine ring in its structure is significant. Piperidine is often found in various alkaloids and has been recognized for its role in the synthesis of pharmaceuticals.
  • Diverse Applications: Given its structure, N-[1-methyl-2-(1-piperidyl)ethyl]-N-phenyl-propanamide could be used in various fields, including:
    • Pharmaceutical research and development.
    • Chemical synthesis processes.
    • Possibly influencing neurological pathways.
  • Structure-Activity Relationship: Understanding the relationship between the structure of this compound and its biological activity could lead to significant insights in drug design.
  • Future Exploration: Scientists are encouraged to explore this compound's properties further. The unique combination of a piperidine moiety and an aromatic amide may lead to novel findings.

In summary, N-[1-methyl-2-(1-piperidyl)ethyl]-N-phenyl-propanamide is a compound that opens doors to various scientific inquiries. Its unique structure and potential applications emphasize the need for continued research in the field of chemistry and pharmacology. As the famous chemist Linus Pauling once said, “The best way to have a good idea is to have a lot of ideas.” So, let’s generate more ideas for this fascinating compound!

Synonyms
Phenampromide
Phenampromid
Fenampromida
129-83-9
Fenampromide
Phenampromidum
Fenampromide [DCIT]
Phenampromide [INN:BAN]
Fenampromida [INN-Spanish]
Phenampromidum [INN-Latin]
EINECS 204-967-1
N-(1-Methyl-2-piperidinoethyl)propionanilide
IDS-NP-019
0600L2M6EZ
PROPIONANILIDE, N-(1-METHYL-2-PIPERIDINOETHYL)-
PHENAMPROMIDE [MI]
PHENAMPROMIDE [INN]
Propanamide, N-(1-methyl-2-(1-piperidinyl)ethyl)-N-phenyl-
DTXSID10911012
N-phenyl-N-(1-piperidin-1-ylpropan-2-yl)propanamide
Phenampromide (INN)
Fenampromida (INN-Spanish)
Phenampromidum (INN-Latin)
Propanamide, N-[1-methyl-2-(1-piperidinyl)ethyl]-N-phenyl-
N-(1-METHYL-2-PIPERIDIN-1-YLETHYL)-N-PHENYLPROPANAMIDE
UNII-0600L2M6EZ
DEA No. 9638
SCHEMBL907886
CHEMBL2104589
DTXCID20810663
D12693
Q7181329
N-[1-Methyl-2-(1-piperidinyl)ethyl]-N-phenylpropanamide #
Propanamide, N-(1-methyl-2-(1-piperidinyl)ethyl)-N-phenyl-(9CI)
204-967-1