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Modafinil

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Identification
Molecular formula
C15H15NO4
CAS number
68693-11-8
IUPAC name
N-(1-methyl-2-phenyl-ethyl)-3-oxo-3-(3,4,5-trimethoxyphenyl)propanamide
State
State

At room temperature, Modafinil is a solid.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
348.50
Boiling point (Kelvin)
621.65
General information
Molecular weight
273.35g/mol
Molar mass
273.3490g/mol
Density
1.1000g/cm3
Appearence

Modafinil appears as a white to off-white, crystalline powder.

Comment on solubility

Solubility of N-(1-methyl-2-phenyl-ethyl)-3-oxo-3-(3,4,5-trimethoxyphenyl)propanamide

The solubility of N-(1-methyl-2-phenyl-ethyl)-3-oxo-3-(3,4,5-trimethoxyphenyl)propanamide is an intriguing aspect to explore, given its complex structure. This compound, like many organic molecules, demonstrates specific solubility characteristics influenced by its functional groups and molecular interactions.

Factors Affecting Solubility

Several factors contribute to the solubility of this compound:

  • Polarity: The presence of the amide functional group can enhance polarity, leading to stronger interactions with polar solvents like water.
  • Structural Features: The bulky aromatic rings can hinder solubility in aqueous environments, affecting how well the compound interacts with other molecules.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the amide bond can also facilitate solubility in polar solvents.

Solubility in Different Solvents

This compound is likely to exhibit:

  • Moderate solubility in polar solvents: Its ability to interact favorably with polar compounds may result in decent solubility.
  • Poor solubility in non-polar solvents: The structure implies that solubility in non-polar solvents could be limited due to significant steric hindrance.

In conclusion, while the exact solubility data might be scarce, understanding the influencing factors can guide prediction and practical applications. As with many complex organic compounds, empirical testing in various solvents would provide definitive insights into its solubility profile.

Interesting facts

Interesting Facts about N-(1-methyl-2-phenyl-ethyl)-3-oxo-3-(3,4,5-trimethoxyphenyl)propanamide

N-(1-methyl-2-phenyl-ethyl)-3-oxo-3-(3,4,5-trimethoxyphenyl)propanamide is an intriguing compound that has garnered attention in various fields of research. Here are some noteworthy facts about this complex molecule:

  • Complex Structure: The compound features a multi-ring structure that incorporates multiple functional groups, making it a fascinating subject for chemists interested in organic synthesis and medicinal chemistry.
  • Biological Activity: Preliminary studies suggest that this compound may have potential pharmacological properties. Compounds with similar structures have been investigated for their effects on the central nervous system and as anti-inflammatory agents.
  • Synthetic Pathways: The synthesis of N-(1-methyl-2-phenyl-ethyl)-3-oxo-3-(3,4,5-trimethoxyphenyl)propanamide often involves intricate synthetic pathways that require advanced organic chemistry techniques. This aspect makes it an excellent case study for students learning about multi-step synthesis.
  • Applications in Medicinal Chemistry: Due to the presence of the phenyl and methoxy groups, the compound is of interest in the field of medicinal chemistry, potentially enabling new avenues for drug development targeting specific receptors in the body.
  • Insights on Structure-Activity Relationships: The study of this compound can provide insights into structure-activity relationships (SAR) which are crucial for understanding how modifications to molecular structure can influence biological activity.

Overall, N-(1-methyl-2-phenyl-ethyl)-3-oxo-3-(3,4,5-trimethoxyphenyl)propanamide serves as a prime example of how complex organic compounds can not only be a challenge to synthesize but also offer vast potential in the field of drug discovery. As one researcher noted, “The beauty of synthetic organic chemistry lies in its ability to create compounds that can change lives.”

Synonyms
23771-15-5
DTXSID20946557
3-Oxo-N-(1-phenylpropan-2-yl)-3-(3,4,5-trimethoxyphenyl)propanimidic acid
RefChem:1068423
DTXCID801374840
N-(alpha-Methylphenethyl)-2-(3,4,5-trimethoxybenzoyl)-acetamide
ACETAMIDE, N-(alpha-METHYLPHENETHYL)-2-(3,4,5-TRIMETHOXYBENZOYL)-