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Propacetamol

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Identification
Molecular formula
C18H22N2O3
CAS number
66532-86-3
IUPAC name
N-(1-methylpyrrolidin-3-yl)-2-phenoxy-N-phenyl-acetamide
State
State

At room temperature, propacetamol is a solid. Given its pharmaceutical applications, it might be found in various preparations like powders or capsules.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
320.39g/mol
Molar mass
320.3930g/mol
Density
1.1310g/cm3
Appearence

Propacetamol is typically available in the form of a white or off-white powder. It may also be processed into tablets or an injectable solution when prepared for medical uses. The compound generally has no distinct odor.

Comment on solubility

Solubility of N-(1-methylpyrrolidin-3-yl)-2-phenoxy-N-phenyl-acetamide

The solubility of N-(1-methylpyrrolidin-3-yl)-2-phenoxy-N-phenyl-acetamide, often referred to as a pharmaceutical compound, is an important characteristic that can affect its bioavailability and therapeutic efficacy. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of both hydrophilic (water-attracting) and hydrophobic (water-repelling) functional groups in the chemical structure plays a crucial role in its solubility profile.
  • pH Level: The solubility can vary significantly with pH, as alterations in the ionization state of the amide group can improve or hinder interaction with solvents.
  • Temperature: Higher temperatures typically enhance solubility, a key consideration in formulation processes.
  • Solvent Type: Since this compound is likely to have varied solubility in different solvents, it is more soluble in non-polar solvents compared to polar ones.

In many cases, compounds like N-(1-methylpyrrolidin-3-yl)-2-phenoxy-N-phenyl-acetamide exhibit limited solubility in water, which poses challenges for formulation in aqueous environments. Therefore, careful selection of excipients and formulation conditions is essential to optimize solubility. Understanding solubility can ultimately guide the development of effective dosage forms and enhance the delivery of this compound in therapeutic applications.

Interesting facts

Exploring N-(1-methylpyrrolidin-3-yl)-2-phenoxy-N-phenyl-acetamide

N-(1-methylpyrrolidin-3-yl)-2-phenoxy-N-phenyl-acetamide is a fascinating compound that has drawn the attention of chemists and pharmacologists alike due to its unique structure and potential applications. Here are some intriguing facts about this compound:

  • Structural Features: This compound features a pyrrolidine ring and both phenoxy and phenyl groups. The presence of these functional groups contributes to its versatility in diverse chemical contexts.
  • Pharmacological Potential: It has been the subject of study for its possible therapeutic applications, particularly in the realm of neurological disorders. Researchers are investigating its interaction with various biological targets, which might lead to new treatments.
  • Agonist Activity: The structural analogs of this compound show promise as agonists for specific receptors in the brain. This could have implications for developing medications aimed at conditions like anxiety and depression.
  • Synthesis Challenges: The synthesis of N-(1-methylpyrrolidin-3-yl)-2-phenoxy-N-phenyl-acetamide can be complex. Synthetic chemists are continually looking for more efficient pathways to create this compound while maintaining integrity in its structure.
  • Interdisciplinary Interest: Apart from chemistry, this compound intersects the fields of medicine, pharmacology, and materials science, showcasing the importance of interdisciplinary approaches in modern scientific research.

Overall, N-(1-methylpyrrolidin-3-yl)-2-phenoxy-N-phenyl-acetamide represents a rich tapestry of opportunity and challenge within the realm of chemical research. As studies continue, who knows what new discoveries may arise concerning its properties and potential uses?