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Dextropropoxyphene

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Identification
Molecular formula
C22H29NO
CAS number
469-62-5
IUPAC name
N-(1-methylpyrrolidin-3-yl)-N,2-diphenyl-acetamide
State
State

At room temperature, dextropropoxyphene is typically found as a solid crystalline substance.

Melting point (Celsius)
39.00
Melting point (Kelvin)
312.15
Boiling point (Celsius)
632.20
Boiling point (Kelvin)
905.35
General information
Molecular weight
339.47g/mol
Molar mass
339.4670g/mol
Density
0.9869g/cm3
Appearence

Dextropropoxyphene generally appears as a white crystalline powder and can sometimes have a faint odor.

Comment on solubility

Solubility of N-(1-methylpyrrolidin-3-yl)-N,2-diphenyl-acetamide

N-(1-methylpyrrolidin-3-yl)-N,2-diphenyl-acetamide is a compound with interesting solubility characteristics that largely depend on its molecular structure. This compound, with a complex aromatic system combined with a pyrrolidine moiety, exhibits unique interactions with solvents. Here are some key points to consider:

  • Polarity: The presence of the polar acetamide group contributes to enhanced solubility in polar solvents such as water and alcohols.
  • Aromatic interactions: The diphenyl groups increase hydrophobic character, allowing for favorable solubility in non-polar solvents like chloroform and benzene.
  • Hydrogen bonding: The potential for hydrogen bonding from the acetamide group may facilitate solubility improvements in various solvent systems.
  • Thermal stability: Typically, solubility can be temperature-dependent; thus, higher temperatures might lead to increased solubility due to enhanced molecular movement.

In summary, N-(1-methylpyrrolidin-3-yl)-N,2-diphenyl-acetamide showcases varying solubility based on the solvent conditions, and it provides a fascinating study of the interplay between polar and non-polar characteristics within a single compound.

Interesting facts

Interesting Facts about N-(1-methylpyrrolidin-3-yl)-N,2-diphenyl-acetamide

N-(1-methylpyrrolidin-3-yl)-N,2-diphenyl-acetamide is a fascinating compound that bridges the realms of organic chemistry and pharmacology. Here are some engaging aspects of this compound:

  • Structural Complexity: This compound features a unique combination of a pyrrolidine ring and diphenyl groups, which can contribute to its biological activity. The presence of nitrogen in the pyrrolidine enhances its reactivity and potential interactions with biological targets.
  • Pharmacological Potential: Compounds with structures similar to N-(1-methylpyrrolidin-3-yl)-N,2-diphenyl-acetamide have been studied for their potential uses in treating various neurological disorders. The incorporation of a pyrrolidine moiety may allow for enhanced interaction with neurotransmitter receptors.
  • Research Significance: It is essential in the development of novel medicinal agents due to its possible roles as a scaffold for synthesizing new drugs. The influence of different substituents on the activity of such compounds is a key area of investigation in medicinal chemistry.
  • Analytical Techniques: The synthesis and characterization of this compound are often explored using various analytical techniques, such as NMR spectroscopy and mass spectrometry, which provide critical insights into its molecular structure and behavior.
  • Interdisciplinary Applications: This compound exemplifies how organic chemistry intersects with pharmacology, allowing scientists to design compounds with specific biological activities. This cross-disciplinary approach can lead to breakthroughs in drug discovery.

In conclusion, N-(1-methylpyrrolidin-3-yl)-N,2-diphenyl-acetamide stands as a testament to the intricate connections between molecular structure and function, showcasing the beauty and complexity that characterizes modern chemical research.

Synonyms
23150-72-3
ACETANILIDE, N-(1-METHYL-3-PYRROLIDINYL)-2-PHENYL-
BRN 0423689
N-(1-Methyl-3-pyrrolidinyl)-2-phenylacetanilide
N-(1-methylpyrrolidin-3-yl)-N,2-diphenylacetamide
RefChem:1075483
DTXSID60945827