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Naphazoline

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Identification
Molecular formula
C14H14N2
CAS number
835-31-4
IUPAC name
N-(1-naphthyl)-4,5-dihydro-1H-imidazol-2-amine
State
State

At room temperature, Naphazoline is generally in a solid state as a crystalline powder. When used in solutions, it is in liquid form.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
232.28g/mol
Molar mass
232.2910g/mol
Density
1.0510g/cm3
Appearence

Naphazoline is typically a white to off-white crystalline powder. It is often found in ophthalmic solutions, appearing as a clear, colorless liquid when dissolved.

Comment on solubility

Solubility of N-(1-naphthyl)-4,5-dihydro-1H-imidazol-2-amine

N-(1-naphthyl)-4,5-dihydro-1H-imidazol-2-amine, a compound known for its unique structure, exhibits interesting solubility characteristics that are worth exploring.

Key Points on Solubility:

  • Polar and Non-Polar Interactions: This compound, containing both polar and non-polar groups, may likely show differential solubility depending on the solvent used. For example, it might be more soluble in polar organic solvents due to the presence of its imidazole moiety.
  • Solvent Choice: Common solvents that can dissolve similar compounds often include DMSO, ethyl acetate, or methanol, but testing is required for precise solubility data.
  • Temperature Dependence: As with many organic compounds, its solubility may increase with temperature, making it worthwhile to investigate how heat affects its dissolution behavior.
  • Effect of Functional Groups: The presence of the naphthyl group could also *stabilize certain interactions*, potentially enhancing solubility in specific mediums.

In summary, understanding the solubility of N-(1-naphthyl)-4,5-dihydro-1H-imidazol-2-amine is crucial for applications in various fields, as it may influence its efficacy and utility in chemical reactions and formulations.

Interesting facts

Exploring N-(1-naphthyl)-4,5-dihydro-1H-imidazol-2-amine

N-(1-naphthyl)-4,5-dihydro-1H-imidazol-2-amine is a fascinating compound that has captured the interest of chemists and researchers alike for its unique structural properties and potential applications. Below are some interesting facts that highlight its significance:

  • Structural Characteristics: The compound contains a naphthalene moiety, which contributes to its aromatic stability and chemical reactivity. The imidazole ring adds a level of versatility, allowing for various substitutions and modifications.
  • Pharmaceutical Potential: Compounds like N-(1-naphthyl)-4,5-dihydro-1H-imidazol-2-amine are investigated for their biological activities. This particular compound may exhibit significant properties, including potential anti-cancer and anti-inflammatory effects.
  • Synthetic Approach: The synthesis of this compound typically involves multi-step organic reactions, showcasing the creativity required in modern organic chemistry. It's a testament to the intricate planning and execution that chemists must undertake to create complex molecules.
  • Investigation in Research: Researchers have been exploring similar imidazole derivatives due to their roles as intermediates in various chemical processes and their functional capabilities in medicinal chemistry. They often serve as important building blocks for the development of new drugs and other functional materials.
  • Interesting Interactions: The presence of the naphthyl group can enhance interactions with biological targets, thus altering the compound’s pharmacokinetics. Understanding these interactions can significantly impact drug design strategies.

In summary, N-(1-naphthyl)-4,5-dihydro-1H-imidazol-2-amine is not just a molecular entity; it represents a gateway to exploring the complex world of organic synthesis and medicinal chemistry. As we continue to delve into its properties and applications, we stand on the cusp of potentially discovering new therapeutic avenues that could benefit human health.

Synonyms
4751-46-6
2-(1-Naphthylamino)-2-imidazoline
1-NAPHTHYLAMINE, N-(2-IMIDAZOLIN-2-YL)-
N-(2-Imidazolin-2-yl)-1-naphthylamine
DTXSID90197170
DTXCID00119661
N-(Naphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
N-naphthalen-1-yl-4,5-dihydro-1H-imidazol-2-amine
SCHEMBL1741683
imidazolidin-2-ylidene-naphthalen-1-yl-amine
N-(2-imidazolidinylidene)-1-naphthalenamine