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Amiloride hydrochloride

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Identification
Molecular formula
C6H5NH(Cl)C(NH)2
CAS number
2016-88-8
IUPAC name
[N'-(1-naphthylmethyl)carbamimidoyl]ammonium;chloride
State
State

At room temperature, this compound is a solid.

Melting point (Celsius)
288.00
Melting point (Kelvin)
561.15
Boiling point (Celsius)
183.00
Boiling point (Kelvin)
456.15
General information
Molecular weight
266.11g/mol
Molar mass
266.1100g/mol
Density
1.4880g/cm3
Appearence

Amiloride hydrochloride typically appears as a white to almost white crystalline powder. It is odorless and is usually available in a hydrated form.

Comment on solubility

Solubility of N'-(1-naphthylmethyl)carbamimidoyl;chloride

The compound N'-(1-naphthylmethyl)carbamimidoyl ammonium chloride, also represented as [N'-(1-naphthylmethyl)carbamimidoyl]ammonium;chloride, exhibits interesting solubility characteristics that can be influenced by several factors:

  • Polar Solubility: As an ammonium salt, it tends to have good solubility in polar solvents, particularly water, due to its ionic nature.
  • Non-Polar Solubility: The presence of the naphthyl group may provide some degree of hydrophobicity, potentially limiting solubility in non-polar solvents.
  • Temperature Dependence: The solubility of this compound is likely to increase with temperature, which is a common trait for many salts.
  • pH Influence: The solubility can also vary with pH, as the ionization state of the ammonium component can change, affecting the compound's overall solubility.

In conclusion, while [N'-(1-naphthylmethyl)carbamimidoyl]ammonium;chloride shows compatibility with polar solvents, it is crucial to consider the environmental conditions that might enhance or inhibit its solubility. As emphasized, its behavior in a solution is notably dependent on factors such as temperature and pH levels.

Interesting facts

Interesting Facts about N'-(1-naphthylmethyl)carbamimidoyl; Ammonium Chloride

N'-(1-naphthylmethyl)carbamimidoyl ammonium chloride is a fascinating compound that serves various roles in both organic synthesis and medicinal chemistry. Here are some intriguing points about this compound:

  • Biological Importance: The naphthylmethyl group in this compound is often associated with biological activity, and compounds that incorporate this moiety have been studied for their potential roles as pharmaceutical agents.
  • Synthesis Versatility: This compound can be synthesized through a variety of methods, allowing for the exploration of different chemical pathways. Its versatility makes it an excellent subject for study in organic reaction mechanisms.
  • Solubility Enhancer: Being a quaternary ammonium salt, it may exhibit properties that enhance the solubility of otherwise insoluble compounds, making it useful in compound formulation and delivery systems.
  • Research Applications: Researchers have utilized this compound in studies dealing with reactive intermediates and catalysis, demonstrating its potential in advancing modern synthetic methodologies.
  • Intermolecular Interactions: The compound's structure allows it to engage in various intermolecular interactions, which can be essential in forming complex structures or influencing reaction pathways.

Overall, N'-(1-naphthylmethyl)carbamimidoyl ammonium chloride is not just a chemical entity; it represents a bridge between fundamental research and practical applications in chemistry and biology. Its unique structure and properties invite scientists to explore the endless possibilities that lie within its molecular framework.