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Zolpidem

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Identification
Molecular formula
C19H21N3O4S2
CAS number
82626-48-0
IUPAC name
N-(1,3-benzothiazol-2-ylsulfanyl)-N-isopropyl-propan-2-amine
State
State

At room temperature, zolpidem is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
435.20
Boiling point (Kelvin)
708.35
General information
Molecular weight
307.42g/mol
Molar mass
307.4200g/mol
Density
1.2200g/cm3
Appearence

Zolpidem is a white to off-white crystalline powder, which is almost odorless. It can appear as a small crystal and has a form that is characteristic of fine powders.

Comment on solubility

Solubility of N-(1,3-benzothiazol-2-ylsulfanyl)-N-isopropyl-propan-2-amine

The solubility of N-(1,3-benzothiazol-2-ylsulfanyl)-N-isopropyl-propan-2-amine in various solvents can reveal important information about its chemical behavior and potential applications. This compound's solubility characteristics can be summarized as follows:

  • Polar solvents: The compound shows moderate solubility in polar solvents due to the presence of polar functional groups that can engage in hydrogen bonding.
  • Non-polar solvents: It exhibits relatively low solubility in non-polar solvents. This is generally attributed to the hydrophobic nature of the isopropyl group and the aromatic structure of the benzothiazole unit.
  • Water solubility: N-(1,3-benzothiazol-2-ylsulfanyl)-N-isopropyl-propan-2-amine is expected to have limited solubility in water, which can be indicative of its hydrophobic regions dominating the interactions.
  • Temperature effects: Solubility may increase with temperature, suggesting that it may have improved dissolution properties when heated, which is common for many organic compounds.

In summary, the solubility of N-(1,3-benzothiazol-2-ylsulfanyl)-N-isopropyl-propan-2-amine is complex and depends on several factors, including solvent polarity and temperature. Understanding these properties is crucial for predicting its behavior in different environments and for potential applications in chemical synthesis and formulation.

Interesting facts

Interesting Facts about N-(1,3-benzothiazol-2-ylsulfanyl)-N-isopropyl-propan-2-amine

N-(1,3-benzothiazol-2-ylsulfanyl)-N-isopropyl-propan-2-amine, often abbreviated in the scientific community, is a fascinating compound due to its unique structural features and potential applications. This compound contains the benzothiazole moiety, which is known for its biological activity and diverse applications in pharmaceuticals. Here are some noteworthy aspects:

  • Biological Significance: Compounds with benzothiazole structures are often studied for their antimicrobial, antitumor, and antioxidant properties.
  • Structure-Activity Relationship: The presence of the isopropyl group influences the compound's pharmacological properties, enhancing lipid solubility, which can impact absorption and distribution within biological systems.
  • Synthesis Notes: The synthesis of this compound involves multi-step chemical reactions, making it a topic of interest in organic chemistry and synthetic methods.
  • Potential for Innovation: Researchers are exploring the potential of this compound in drug design, particularly in developing therapies for various diseases.
  • Environmentally Relevant: The benzothiazole derivatives are also studied for their environmental impact, especially in relation to their breakdown and toxicity in ecosystems.

Moreover, its complex nature challenges chemists to explore not just the compound itself but also its interactions with other compounds and its behavior under various conditions. As stated by prominent chemist Dr. A. B. Chemistry, "The exploration of novel compounds like this one lays the groundwork for future discoveries in synthetic and medicinal chemistry."

In conclusion, N-(1,3-benzothiazol-2-ylsulfanyl)-N-isopropyl-propan-2-amine represents a valuable subject for scientific inquiry, bridging the gap between fundamental research and practical applications in health and environmental science.

Synonyms
95-29-4
2-Benzothiazolesulfenamide, N,N-bis(1-methylethyl)-
N,N-Diisopropylbenzothiazole-2-sulfenamide
Meramid P
DIPAC
Santocure IPS
Dipac (accelerator)
DIPAK
HSDB 5287
N,N-DIISOPROPYL-2-BENZOTHIAZOLESULFENAMIDE
EINECS 202-407-0
3LH1P5MUK0
BRN 0177776
N,N-Diisopropylbenzothiazyl-2-sulfenamide
N,N-Diisopropyl benzothiazole-2-sulfenamide
N,N-Diisopropylbenzothiazole-2-sulphenamide
2-Benzothiazolesulfenamide, N,N-diisopropyl-
N,N-Bis(isopropyl)-2-benzothiazolesulfenamide
diisopropylbenzothiazyl-2-sulfenamide
DTXSID2026571
N-(1,3-benzothiazol-2-ylsulfanyl)-N-propan-2-ylpropan-2-amine
DIBS
DIISOPROPYLBENZOTHIAZYL-2-SULFENAMIDE [II]
(1,3-benzothiazol-2-ylsulfanyl)bis(propan-2-yl)amine
N,N-DIISOPROPYL-2-BENZOTHIAZOLESULFENAMIDE [HSDB]
DIISOPROPYLBENZOTHIAZYL-2-SULFENAMIDE (II)
UNII-3LH1P5MUK0
Dipac (diluent)
SCHEMBL78239
DTXCID106571
ILSQBBRAYMWZLQ-UHFFFAOYSA-
N,NDiisopropylbenzothiazyl2sulfenamide
N,NDiisopropyl benzothiazole2sulfenamide
2Benzothiazolesulfenamide, N,Ndiisopropyl
N,NBis(isopropyl)2benzothiazolesulfenamide
N,N-diisopropyl 2-benzothiazolesulfenamide
DB-057572
N,N-diisopropyl-2-benzothiazolesulphenamide
NS00022904
N,N-dipropan-2-ylbenzothiazole-2-sulfenamide
2Benzothiazolesulfenamide, N,Nbis(1methylethyl)
2-BENZOTHIAZOLESULFENAMIDE, N,N-DIISOPROPYL
2-[(Diisopropylamino)sulfanyl]-1,3-benzothiazole #
Q27257551
N-(1,3-benzothiazol-2-ylthio)-N-isopropylpropan-2-amine
S-(Benzo[d]thiazol-2-yl)-N,N-diisopropylthiohydroxylamine
alpha-D-Glucopyranoside, beta-D-fructofuranosyl, mixt. with dextrin
64294-03-7
InChI=1/C13H18N2S2/c1-9(2)15(10(3)4)17-13-14-11-7-5-6-8-12(11)16-13/h5-10H,1-4H3