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Phenazone

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Identification
Molecular formula
C11H12N2O
CAS number
60-80-0
IUPAC name
N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-2-nitro-benzamide
State
State

At room temperature, phenazone is in a solid state. It is stable under normal conditions and should be kept in a well-closed container to prevent it from absorbing moisture from the air.

Melting point (Celsius)
156.50
Melting point (Kelvin)
429.65
Boiling point (Celsius)
342.90
Boiling point (Kelvin)
616.05
General information
Molecular weight
188.23g/mol
Molar mass
188.2300g/mol
Density
1.2970g/cm3
Appearence

Phenazone, also known as antipyrine, appears as a white crystalline powder. It is odorless and has a bitter taste. The crystals are usually shiny and can form as needles when crystallized from an appropriate solvent.

Comment on solubility

Solubility of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-2-nitro-benzamide

N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-2-nitro-benzamide, a complex organic compound, exhibits unique solubility characteristics that are crucial for its applications in various fields.

Solubility Characteristics:

  • Polarity: This compound is polar due to the presence of nitro and carbonyl functional groups, which generally enhances solubility in polar solvents.
  • Solvent Interaction: It tends to dissolve well in solvents like methanol, dimethyl sulfoxide (DMSO), and possibly some other polar organic solvents.
  • Water Solubility: Despite its polar character, the overall structure may limit water solubility, possibly resulting in only limited solubility due to hydrophobic phenyl and ethyl groups.
  • Temperature Influence: Solubility often increases with temperature, making it essential to consider conditions during synthesis and application.

The overall solubility of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-2-nitro-benzamide is a balance of its contrasting functional groups and molecular structure. As stated, "the solubility of a compound is determined by the attraction between solute and solvent molecules." Thus, understanding this balance helps predict its behavior in various environments.

Interesting facts

Interesting Facts About N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-2-nitro-benzamide

N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-2-nitro-benzamide, often recognized for its complex structure and potential industrial applications, is a fascinating compound in the realm of organic chemistry.

Key Highlights

  • Diverse Applications: This compound showcases versatility, with potential uses in pharmaceuticals, particularly in creating drugs that target specific inflammatory or cancerous pathways.
  • Unique Structure: The presence of a pyrazole ring, alongside an aromatic nitro substituent, contributes to the compound's unique reactivity and biological activity.
  • Potential Therapeutic Uses: Compounds containing pyrazole moieties are often explored for their anti-inflammatory and analgesic properties, making them suitable candidates for further medicinal research.
  • Synthetic Relevance: The synthesis of this compound often involves multi-step organic reactions, highlighting the complexity and creativity involved in organic synthesis.

As noted by chemists, "The unexpected reactions and interactions of aromatic compounds challenge our understanding of chemical behavior and reactivity." This underscores the compound's importance in academia and industry, where understanding its behavior can lead to significant advancements in material science and drug design.

The study of compounds like N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-2-nitro-benzamide not only enhances our chemical knowledge but also paves the way for innovative solutions in health and technology.

Synonyms
BENZAMIDE, N-ANTIPYRINYL-N-ETHYL-o-NITRO-
15054-47-4
TA 9
N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-ethyl-2-nitrobenzamide
N-Antipyrinyl-N-ethyl-o-nitrobenzamide
BRN 0586706
N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-N-ethyl-2-nitrobenzamide
Oprea1_560363
DTXSID30164568
SR-01000231961
SR-01000231961-1