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Phenazone

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Identification
Molecular formula
C11H12N2O
CAS number
60-80-0
IUPAC name
N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-3-nitro-benzamide
State
State
At room temperature, Phenazone is a solid. It is typically handled and stored in this solid form for pharmaceutical purposes.
Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
395.80
Boiling point (Kelvin)
668.95
General information
Molecular weight
188.23g/mol
Molar mass
188.2260g/mol
Density
1.3000g/cm3
Appearence
Phenazone typically appears as a white crystalline powder. Its crystals may also appear colorless or faintly colored, appearing translucent in nature.
Comment on solubility

Solubility of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-3-nitro-benzamide

The solubility of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-3-nitro-benzamide is influenced by several factors, primarily its molecular structure and the presence of functional groups. This compound features both polar and non-polar characteristics, which can significantly affect its interaction with solvents.

Key Points to Consider:

  • Polarity: The presence of the nitro group and carbonyl functionality suggests potential for increased solubility in polar solvents, such as water.
  • Hydrophobic Regions: The phenyl and ethyl groups contribute hydrophobic properties, which may limit solubility in aqueous environments.
  • Solvent Type: While the compound may exhibit some solubility in organic solvents (e.g., ethanol, methanol), it could remain relatively insoluble in highly polar solvents.

In summary, one might expect this compound to demonstrate moderate solubility in certain organic solvents while potentially facing challenges in fully dissolving in aquatic solutions due to its mixed polarities. Understanding its solubility profile is essential for applications in pharmaceutical formulations and chemical syntheses.

Interesting facts

Interesting Facts about N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-3-nitro-benzamide

N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-3-nitro-benzamide, more commonly referred to by its abbreviated name, is a compound that showcases the fascinating interplay of heterocyclic chemistry and pharmacology. This compound has garnered interest for its potential applications in medicinal chemistry. Here are some intriguing details about this compound:

  • Pharmacological Properties: Many derivatives of benzamide are known for their diverse biological activities, including anti-inflammatory, analgesic, and antitumor effects. The structural components in this compound suggest possible interactions with biological targets.
  • Synthetic Routes: The synthesis of this compound typically involves multiple reaction steps that can include the formation of pyrazole rings and subsequent functionalizations. Understanding these pathways is fundamental in designing similar molecules.
  • Structural Diversity: The presence of the nitro group, the methyl substituents, and the phenyl moiety contributes significantly to the compound's activity profile. Research in drug design often leverages structure-activity relationships (SAR) to maximize efficacy.
  • Interdisciplinary Significance: Compounds like this one bridge various disciplines, including medicinal chemistry, organic synthesis, and pharmacology, highlighting the collaborative nature of modern scientific research.

As a chemist or a chemistry student, recognizing the potential of compounds such as N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-3-nitro-benzamide can ignite a passion for exploration and innovation in the field. Such molecules may pave the way for the next generation of therapeutic agents, reinforcing the idea that each compound holds the promise of discovery:

"Every molecule tells a story, and through careful study, we unlock its secrets." - Anonymous Chemist

Overall, N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-3-nitro-benzamide represents a captivating example of how even complex structures can lead to groundbreaking developments in science.

Synonyms
BENZAMIDE, N-ANTIPYRINYL-N-ETHYL-m-NITRO-
15166-20-8
TA 8
N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-ethyl-3-nitrobenzamide
N-Antipyrinyl-N-ethyl-m-nitrobenzamide
BRN 0586658
N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-N-ethyl-3-nitrobenzamide
Oprea1_524198
DTXSID70164845
AB00105539-01
SR-01000232473
SR-01000232473-1