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Phenazone

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Identification
Molecular formula
C11H12N2O
CAS number
60-80-0
IUPAC name
N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide
State
State

At room temperature, Phenazone is in a solid state. The compound is typically stable under normal conditions of use and storage.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
288.00
Boiling point (Kelvin)
561.15
General information
Molecular weight
220.25g/mol
Molar mass
220.2480g/mol
Density
1.2180g/cm3
Appearence

Phenazone generally appears as a white crystalline powder. It is odorless and has a bitter taste. The compound's crystalline form is due to the arrangement of its molecules in a precise, repetitive pattern.

Comment on solubility

Solubility of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide

N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide is a compound that exhibits distinct solubility characteristics, which play a critical role in its applications and behavior in various environments.

The solubility of this compound can be influenced by several factors, including:

  • Polarity: N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide contains both polar and nonpolar functional groups, making it a moderately polar compound.
  • Solvent Interaction: It is likely to be more soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), rather than in water due to its hydrophobic characteristics.
  • Temperature: Increased temperature typically enhances solubility; thus, warming the solvent may increase the amount of compound that can dissolve.

In many practical situations, this compound's solubility can be summarized with the statement: "The solubility is dependent on the nature of the solvent and specific conditions." This emphasizes that understanding the solubility profile is crucial for applications in medicinal chemistry and material sciences where solubility directly affects bioavailability and stability.

Researchers often need to consider employing co-solvents or modifying the compound structure to enhance solubility for desired applications.

Interesting facts

Interesting Facts about N-(1,5-Dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide

N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide is a fascinating compound that captivates the interest of chemists and researchers alike. This compound belongs to a class known as pyrazoles, which are five-membered aromatic rings harboring nitrogen atoms. Below are some key points that highlight its significance:

  • Pharmacological Activity: Compounds containing pyrazole moieties have been extensively studied for a variety of biological activities, including anti-inflammatory, analgesic, and antitumor effects. The unique structure of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide could also suggest potential therapeutic applications.
  • Synthetic Pathways: The synthesis of this compound often involves specific multistep reactions that can illustrate fundamental principles of organic chemistry, such as nucleophilic substitution and decarboxylation. These reactions provide insights into tailored compound design.
  • Research Potential: With growing interest in developing novel drugs, this compound may serve as a lead compound, inspiring modifications to enhance its efficacy or reduce side effects.
  • Structure-Activity Relationship (SAR): Understanding how alterations in its structure affect biological activity is a key area of research, contributing to the design of more effective chemical agents.

As chemists delve into the intricacies of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide, they quote Albert Einstein: "The important thing is not to stop questioning. Curiosity has its own reason for existing." This captures not only the essence of studying such compounds but also the quest to unravel more about their roles and functionalities within biological systems.

In summary, N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)benzamide serves as an exemplary nexus where organic chemistry, pharmacology, and innovative research converge, making it a subject worthy of exploration.

Synonyms
4-Benzamidoantipyrine
N-Antipyrinylbenzamide
BRN 0036367
Antipyrine, 4-benzamido-
5702-68-1
1-Phenyl-2,3-dimethyl-4-benzoylamino-5-pyrazolone
BENZAMIDE, N-ANTIPYRINYL-
DTXSID50205629
4-25-00-03579 (Beilstein Handbook Reference)
Benzamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-
Antipyrine, 4-benzamido-(7CI)
DTXCID30128120
N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)benzamide
Antipyrine, 4-benzamido- (7CI)
ChemDiv3_000032
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-benzamide
Oprea1_150486
Oprea1_406438
MLS000526562
CHEMBL1432031
HMS1473B10
HMS2191H17
STK084120
AKOS000747541
WAY-112801
IDI1_019350
NCGC00176102-01
SMR000117036
SR-01000393028
SR-01000393028-1