Skip to main content

Phenylbutazone

ADVERTISEMENT
Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide
State
State

Phenylbutazone is a solid at room temperature.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
308.37g/mol
Molar mass
308.3720g/mol
Density
1.2000g/cm3
Appearence

Phenylbutazone typically appears as a white or light-yellow crystalline powder. It is odorless or may have a very slight odor.

Comment on solubility

Solubility of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide

The solubility of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide can be influenced by several factors, making it a fascinating compound to examine in terms of its interactions with solvents.

In general, the solubility of compounds such as this one can be outlined as follows:

  • Polarity: The presence of functional groups can enhance or reduce polarity, affecting solubility in polar versus non-polar solvents.
  • Hydrogen Bonding: Ability to form hydrogen bonds can increase solubility in polar solvents, while a lack thereof can lead to poor solubility.
  • Temperature: Generally, solubility increases with temperature, particularly in solid compounds, allowing for better dissolution in solvents.
  • pH Levels: Changes in pH can affect the ionization state of a compound, influencing its solubility in aqueous environments.

For N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide, it is typically expected to have moderate solubility in common organic solvents like ethanol and DMSO, but limited solubility in water due to its relatively hydrophobic character. This characteristic highlights the **importance of solvent selection** in the dissolution process, which may often determine the practicality of the compound's application.

As a takeaway, one might say, "Understanding the solubility properties of a compound is not merely a matter of chemistry; it opens doors to myriad applications and interactions." Thus, further experimental investigation is crucial for a detailed understanding of this compound's solubility profile in various conditions.

Interesting facts

Interesting Facts about N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide

N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide is a fascinating compound that lies at the intersection of medicinal chemistry and organic synthesis. This compound incorporates a pyrazole structure, which is notable for its diverse biological activities. Here are some intriguing facts about this compound:

  • Pharmacological Potential: Compounds containing the pyrazole moiety have been studied extensively for their potential as anti-inflammatory, analgesic, and anticancer agents. The unique structure of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide may contribute to novel therapeutic applications.
  • Synthetic Versatility: The synthesis of such complex molecules often involves multiple reaction steps that can be challenging yet rewarding. Researchers explore various synthetic pathways, which not only enhance their creativity but also expand their knowledge of organic reaction mechanisms.
  • Structure-Activity Relationship (SAR): Understanding how changes to the molecular framework affect biological activity is crucial in drug development. The evaluation of N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide can provide insights into how specific substitutions influence its pharmacological properties.
  • Chemical Stability: The stability of this compound under various conditions is an essential area of research. Knowing how stable the compound is can help in determining its storage requirements, as well as its suitability for pharmaceutical applications.
  • Research Applications: This compound serves as a valuable building block in the synthesis of further derivatives that may exhibit enhanced efficacy or reduced toxicity. Its exploration lends itself to advancements in both organic chemistry and drug discovery.

In summary, N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)butanamide represents not only a promising subject of study in the realm of pharmacology but also a rich area for exploration in synthetic organic chemistry. As researchers continue to elucidate the intricacies of such compounds, they pave the way for innovative solutions to contemporary health challenges.

Synonyms
BUTYRAMIDE, N-ANTIPYRINYL-
N-Antipyrinylbutyramide
4417-84-9
BRN 0620886
1-Phenyl-2,3-dimethyl-4-butyrylamino-5-pyrazolone
DTXSID30196061
Butanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-
DTXCID40118552
5-25-14-00100 (beilstein handbook reference)
N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)butanamide
n-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)butyramide
N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)butanamide
CBMicro_035651
Oprea1_172034
Oprea1_261591
AKOS001630554
BIM-0035532.P001
CS-0297170
AG-205/08035038
SR-01000454192
SR-01000454192-1
Z27661936