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N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide

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Identification
Molecular formula
C14H15N3O3
CAS number
220991-20-8
IUPAC name
N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide
State
State
The compound is typically in a solid state at room temperature, appearing as a crystalline solid.
Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
447.80
Boiling point (Kelvin)
720.95
General information
Molecular weight
273.30g/mol
Molar mass
273.2980g/mol
Density
1.2110g/cm3
Appearence

The compound appears as a crystalline solid.

Comment on solubility

Solubility of N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide

The solubility of N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide can be influenced by several factors, particularly its molecular structure and polarity. In general terms, this compound exhibits:

  • Low to Moderate Water Solubility: Due to the presence of both hydrophobic benzamide and aromatic groups, along with polar nitro and pyridine functionalities, its solubility in water may not be highly significant.
  • Solubility in Organic Solvents: Conversely, this compound is likely to demonstrate good solubility in organic solvents such as dimethyl sulfoxide (DMSO), ethanol, or methanol. This favors the dissolution of non-polar and polar components alike.
  • pH Dependency: The solubility might also be pH-dependent, as changes in the acidity can affect the ionization state of the molecule, potentially enhancing solubility in various media.

As a general rule, compounds with > a log P (partition coefficient) value are usually less soluble in water but can dissolve in organic solvents. Therefore, understanding the solubility profile of N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide is critical for its application in biological and chemical processes.

In conclusion, the overall solubility characteristics of N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide make it a compound of interest, especially when considering its interactions in various solvent systems.

Interesting facts

Introduction to N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide

N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide is an intriguing compound that blends elements of both organic chemistry and medicinal chemistry. This compound belongs to the class of amides, which are essential in various biological processes and pharmaceutical applications.

Key Attributes

  • Diverse Applications: This compound has potential applications in drug development due to its unique structure, which may interact with biological targets in novel ways.
  • Structural Features: The presence of both a pyridine moiety and a nitro group contributes to the compound's reactivity and biological activity, making it a subject of interest in synthetic organic chemistry.
  • Research Potential: Scientific studies exploring the pharmacological properties of similar compounds highlight their potential in treating various diseases, including neurodegenerative disorders.

Research Insights

Despite being a relatively complex compound, ongoing research may reveal:

  • Mechanistic Pathways: Understanding how N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide interacts at the molecular level can open new avenues for therapeutic interventions.
  • Cosmetic and Agricultural Use: Beyond medical applications, similar compounds are often explored for uses in cosmetics and agrochemicals, highlighting their versatile nature in different fields.

Conclusion

In summary, N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitro-benzamide stands out as an important compound within the landscape of organic chemistry and pharmacology. As research continues, there is anticipation for its potential to contribute crucial insights into chemical reactivity and biological functions.

Synonyms
T546QZ99P4
UNII-T546QZ99P4
1,2,5,6-Tetrahydro-1,3-dimethyl-4-(4-nitrobenzamido)pyridine
1702-19-8
Benzamide, 4-nitro-N-(1,2,3,6-tetrahydro-1,5-dimethyl-4-pyridinyl)-
DTXSID10274553
N-(1,5-dimethyl-3,6-dihydro-2H-pyridin-4-yl)-4-nitrobenzamide