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Bendazac

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Identification
Molecular formula
C12H14Cl2N2
CAS number
2012-77-7
IUPAC name
N-(1H-benzimidazol-2-ylmethyl)-2-chloro-N-(2-chloroethyl)ethanamine
State
State

At room temperature, Bendazac is found in a solid state. It is stable under standard temperature and pressure conditions.

Melting point (Celsius)
193.00
Melting point (Kelvin)
466.00
Boiling point (Celsius)
351.00
Boiling point (Kelvin)
624.00
General information
Molecular weight
282.17g/mol
Molar mass
282.1690g/mol
Density
1.2300g/cm3
Appearence

Bendazac, also known as N-(1H-benzimidazol-2-ylmethyl)-2-chloro-N-(2-chloroethyl)ethanamine, typically appears as a white to off-white crystalline solid. It is insoluble in water but soluble in organic solvents such as ethanol and acetone.

Comment on solubility

Solubility of N-(1H-benzimidazol-2-ylmethyl)-2-chloro-N-(2-chloroethyl)ethanamine

N-(1H-benzimidazol-2-ylmethyl)-2-chloro-N-(2-chloroethyl)ethanamine is a compound with a unique structure that influences its solubility characteristics.

Key points about its solubility include:

  • Solvent Compatibility: This compound is expected to be soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), which can effectively solvate its molecular structure.
  • Water Solubility: Limited solubility in water may be anticipated due to the presence of hydrophobic aromatic rings and chlorine substituents, which decrease overall polarity.
  • Temperature Effects: Like many amines, solubility may increase with temperature, suggesting that higher temperatures could enhance dissolution rates in suitable solvents.

Overall, while the solubility of this compound depends significantly on its chemical environment and temperature, its primary solvation may be realized in non-polar to mildly polar organic solvents.
As such, careful selection of solvent is crucial for effective application in laboratory settings.

Interesting facts

Interesting Facts about N-(1H-benzimidazol-2-ylmethyl)-2-chloro-N-(2-chloroethyl)ethanamine

N-(1H-benzimidazol-2-ylmethyl)-2-chloro-N-(2-chloroethyl)ethanamine is a fascinating compound characterized by its unique structural components and potential applications in various fields. Here are some intriguing details:

  • Pharmacological Relevance: This compound features a benzimidazole moiety, which is known for its significance in medicinal chemistry. Compounds containing benzimidazole have shown promising activities, including anti-inflammatory, antifungal, and anticancer properties.
  • Substituent Diversity: The presence of two chloro groups in its structure introduces unique electronic and steric properties, potentially influencing the reactivity and biological activity of the compound.
  • Mechanism of Action: Compounds similar to this one have been studied for their ability to interact with biological targets such as enzymes and receptors. Their mechanisms often involve inhibition or modulation of key metabolic pathways.
  • Research Significance: This compound can serve as a valuable starting point for further chemical modifications aimed at enhancing its therapeutic efficacy or reducing toxicity, making it a subject of interest for ongoing chemical research.
  • Numerous Analogues: Given its structural complexity, variations of this compound may lead to a whole library of analogues, each with potential new properties and activities. The exploration of such analogues can vastly expand the understanding of this chemical class.

As research continues, N-(1H-benzimidazol-2-ylmethyl)-2-chloro-N-(2-chloroethyl)ethanamine stands out as a noteworthy compound in the quest for innovative pharmaceutical agents. Its intricate design showcases the beautiful complexity of chemical synthesis and the endless possibilities that emerge from it.

Synonyms
3689-77-8
2-(Bis(beta-chloroethyl)aminomethyl)benzimidazole
Dimezol 14
1H-Benzimidazole-2-methanamine, N,N-bis(2-chloroethyl)-
BENZIMIDAZOLE, 2-(BIS-(2-CHLOROETHYL)AMINOMETHYL)-
DTXSID90958086
NSC 23891
2-(bis(2-chloroethyl)aminomethyl)benzimidazole
N-[(1H-Benzimidazol-2-yl)methyl]-2-chloro-N-(2-chloroethyl)ethan-1-amine