N-(1H-indol-3-ylmethyleneamino)pyridine-4-carboxamide

Identification

Molecular formula

C₁₅H₁₂N₄O

CAS number

5053-32-3

IUPAC name

N-(1H-indol-3-ylmethyleneamino)pyridine-4-carboxamide

State

The compound is in a solid state at room temperature. It typically forms crystalline powder with a stable form under normal conditions. The substance is handled in its solid form for most laboratory applications.

Melting point (Celsius)

210.00

Melting point (Kelvin)

483.15

Boiling point (Celsius)

435.00

Boiling point (Kelvin)

708.15

General information

Molecular weight

265.29g/mol

Molar mass

265.2930g/mol

Density

1.3245g/cm³

Appearence

This compound is typically a solid at room temperature, often appearing as a crystalline powder. The color can range from pale yellow to off-white, depending on the specific conditions and purity of the compound. It is usually opaque with a flat texture.

Comment on solubility

Solubility of N-(1H-indol-3-ylmethyleneamino)pyridine-4-carboxamide

N-(1H-indol-3-ylmethyleneamino)pyridine-4-carboxamide, with the chemical formula C₁₅H₁₂N₄O, exhibits intriguing solubility characteristics that are important for its applications. The solubility of this compound can be influenced by various factors, including:

Polarity: The presence of both an indole moiety and a pyridine structure affects the overall polarity of the molecule, which can enhance its solubility in polar solvents.
Hydrogen Bonding: The functional groups in the compound allow for potential hydrogen bonding with solvent molecules, leading to increased solubility in certain conditions.
pH Levels: Solubility may vary with pH; altering the ionization of the amine groups can change the solubility in aqueous solutions.

In general, this compound tends to have moderate solubility in common organic solvents such as DMSO (Dimethyl sulfoxide) and methanol, while its solubility in water may be limited. For example, one might say:

"The solubility in organic solvents often suggests that N-(1H-indol-3-ylmethyleneamino)pyridine-4-carboxamide can be effectively utilized in various biological and chemical environments."

Understanding the solubility of this compound is crucial for its application in pharmaceutical formulations, where solubility plays a vital role in bioavailability and therapeutic effectiveness. As with most compounds, in-depth characterization through experimentation is essential to draw definitive conclusions regarding its solubility across different solvent systems.

Interesting facts

Interesting Facts about N-(1H-indol-3-ylmethyleneamino)pyridine-4-carboxamide

N-(1H-indol-3-ylmethyleneamino)pyridine-4-carboxamide is a fascinating compound that presents a unique structure combining two important heterocyclic moieties: indole and pyridine. Both of these components are crucial in pharmaceuticals and biochemistry, contributing to the compound’s potential applications.

Key Highlights:

Indole and Pyridine: Indole is known for its role in various biochemical processes and its presence in many natural products, while pyridine is commonly found in pharmaceuticals and agrochemicals.
Biological Activity: Many derivatives of indole and pyridine exhibit pharmacological activities. This compound may have relevance in medicinal chemistry, potentially serving as a framework for developing novel drugs.
Synthesis: The synthesis of compounds like this often involves intricate synthetic pathways, showcasing the skill required in organic chemistry to construct complex structures.
Research Interest: Due to its unique structure, this compound has garnered interest for studies related to cancer therapeutics, anti-inflammatory agents, and more.

As chemists explore the properties of N-(1H-indol-3-ylmethyleneamino)pyridine-4-carboxamide, they emphasize the importance of structure-activity relationships (SAR) in the development of effective medicinal compounds. The interplay between its indole and pyridine groups may provide insights into optimizing the compound’s pharmacological properties.

In conclusion, this compound is not just a representation of organic synthetic chemistry but also a potential player in the vast realm of drug discovery. As we delve deeper into its study, the possibilities in therapeutic applications are indeed exciting!

Synonyms

HMS2517O05