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Melatonin

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Identification
Molecular formula
C13H16N2O
CAS number
73-31-4
IUPAC name
N-[2-(1H-indol-3-yl)ethyl]pyridine-4-carboxamide
State
State

Melatonin is typically found in solid state at room temperature.

Melting point (Celsius)
116.50
Melting point (Kelvin)
389.65
Boiling point (Celsius)
373.90
Boiling point (Kelvin)
647.05
General information
Molecular weight
232.28g/mol
Molar mass
232.2780g/mol
Density
1.1740g/cm3
Appearence

Melatonin appears as a white to off-white powder. It is crystalline in nature and generally soluble in organic solvents such as ethanol and methanol.

Comment on solubility

Solubility of N-[2-(1H-indol-3-yl)ethyl]pyridine-4-carboxamide

The solubility of N-[2-(1H-indol-3-yl)ethyl]pyridine-4-carboxamide is a notable feature, influenced by its structure and functional groups. Understanding its solubility can help predict its behavior in various environments and applications.

Factors Affecting Solubility

  • Polarity: The presence of polar functional groups often enhances solubility in polar solvents, whereas nonpolar regions may promote solubility in organic solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly increase solubility in water and other polar solvents.
  • Structural Characteristics: The indole and pyridine moieties can interact differently with solvents, impacting the overall solubility profile.

It is generally observed that compounds featuring a balance of hydrophobic and hydrophilic characteristics exhibit better solubility in a range of solvents. In the case of N-[2-(1H-indol-3-yl)ethyl]pyridine-4-carboxamide, one might find it moderately soluble in organic solvents, but the exact solubility depends on precise conditions such as temperature and pH.

Practical Implications

For practical applications, knowing the solubility behavior is crucial. It can affect:

  • **Drug formulation**: Solubility impacts bioavailability.
  • **Chemical reactions**: Solvent choice can influence reaction kinetics and equilibria.
  • **Environmental interactions**: Understanding solubility helps in assessing the compound's fate in the environment.

Thus, evaluating the solubility of N-[2-(1H-indol-3-yl)ethyl]pyridine-4-carboxamide is essential for both its applications and its interactions within biological and chemical contexts.

Interesting facts

Exploring N-[2-(1H-indol-3-yl)ethyl]pyridine-4-carboxamide

N-[2-(1H-indol-3-yl)ethyl]pyridine-4-carboxamide, often abbreviated as a complex name, is a fascinating compound that draws interest from various fields, particularly in medicinal chemistry and pharmacology. Here are some interesting facts about this intriguing molecule:

  • Biological Significance: This compound contains an indole moiety, which is notable for its presence in numerous biologically active compounds. Indoles are known for their roles in neurotransmission, particularly in the synthesis of serotonin.
  • Potential Pharmacological Applications: Researchers are investigating derivatives of this compound for their potential therapeutic effects, especially as anti-cancer agents or anti-inflammatory compounds.
  • Structural Diversity: The combination of an indole and a pyridine ring creates a unique structural diversity that could lead to varied biological activities, making it a promising candidate for drug design.
  • Impact of Functional Groups: The carboxamide functional group contributes to the compound's polarity and aqueous solubility, making it potentially active in biological systems.
  • Research & Development: Ongoing studies are looking at the modification of this compound to enhance its efficacy and selectivity in targeting specific biological pathways.

In summary, N-[2-(1H-indol-3-yl)ethyl]pyridine-4-carboxamide stands as a testament to the intricate relationship between structure and function in chemical compounds. As scientists continue to unveil its properties and potential applications, this compound remains a subject of great intrigue in the world of chemistry.

Synonyms
Oprea1_090712
Oprea1_689528
AKOS000545689
CCG-278508
Z26395434