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Disulfiram

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Identification
Molecular formula
C10H20N2S4
CAS number
97-77-8
IUPAC name
N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide
State
State

At room temperature, Disulfiram is in the form of a solid, crystalline powder. It is stable under normal conditions, but should be kept away from strong oxidizing agents.

Melting point (Celsius)
70.50
Melting point (Kelvin)
343.65
Boiling point (Celsius)
252.30
Boiling point (Kelvin)
525.45
General information
Molecular weight
296.54g/mol
Molar mass
296.5400g/mol
Density
1.8000g/cm3
Appearence

Disulfiram appears as a white to off-white crystalline powder. It is tasteless and has no odor.

Comment on solubility

Solubility of N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide

N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide is a fascinating compound with unique solubility properties. Understanding its solubility is crucial for its usage in various chemical contexts.

When discussing solubility, it is important to consider several factors:

  • Polarity: The presence of acetamide groups typically suggests that this compound may exhibit polar characteristics, which can enhance its solubility in polar solvents, such as water.
  • Hydrogen bonding: The capability of forming hydrogen bonds due to amide linkages can contribute positively to solubility in aqueous solutions.
  • Disulfide bond: The presence of the disulfide bond may limit the solubility in certain conditions, potentially leading to precipitation in non-polar solvents.

Overall, while N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide is likely to be soluble in polar solvents, particularly water, its solubility can be quite variable depending on the surrounding conditions, such as temperature and solvent composition. As with many compounds, it might be prudent to conduct specific solubility tests for precise applications.

In conclusion, the solubility of N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide is influenced by its molecular structure, including:

  • Polarity
  • Potential for hydrogen bonding
  • Presence of disulfide bonds

Understanding these factors will guide researchers in predicting behavior in various solvent systems.

Interesting facts

Interesting Facts about N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide

N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide is a fascinating compound with intriguing chemical characteristics and potential applications. Here are some compelling points to consider:

  • Biochemical Importance: This compound contains a disulfide linkage, which is crucial in biological systems. Disulfide bonds play significant roles in the structure and function of proteins, influencing their stability and activity.
  • Potential Antioxidant Activity: Compounds that contain sulfur are often studied for their antioxidant properties. The presence of disulfide could suggest a role in scavenging free radicals, which might be beneficial in various medicinal applications.
  • Drug Development: The compound's structural features make it a potential candidate for drug design. Modifications to the acetamido and disulfanyl groups may lead to new therapeutic agents targeting specific diseases.
  • Research Applications: Its unique structure allows it to serve as a valuable probe in biochemical studies, particularly in research focused on redox biology, where the formation and breaking of disulfide bonds are integral.

As a student or scientist, delving into the properties and reactions of N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide can provide insights into the vast world of organic chemistry and its implications in biological systems. Quote from a popular chemistry textbook: "Understanding the interplay between structure and function is key to advancing our knowledge in biochemical pathways."

In summary, N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide is more than just a chemical formula; it represents the intersection of organic chemistry and biochemistry, offering a gateway to new scientific discoveries.

Synonyms
N,N'-(Dithiodiethylene)bisacetamide
211-338-5
2-Acetamidoethyl disulfide
638-44-8
Disulfide, bis(acetamidoethyl)
Bis(acetamidoethyl)disulfide
Cystamine, N,N'-diacetyl-
N-[2-(2-acetamidoethyldisulfanyl)ethyl]acetamide
Acetamide, N,N-(dithiodiethylene)di-
NSC 175859
Acetamide, N,N'-(dithiodiethylene)bis-
N,N'-(Dithiodi-2,1-ethanediyl)bisacetamide
Acetamide, N,N'-(dithiodi-2,1-ethanediyl)bis-
ACETAMIDE, N,N-DITHIODIETHYLENEDI-
N-{2-[(2-ACETAMIDOETHYL)DISULFANYL]ETHYL}ACETAMIDE
Bis[acetamidoethyl]disulfide
Disulfide, bis[acetamidoethyl]
N,N'-(Disulfanediylbis(ethane-2,1-diyl))diacetamide
EINECS 211-338-5
N,N-Dithiodiethylenediacetamide
BRN 1783915
n,n'-diacetylcystamine
acetamidoethyl disulfide
Cystamine,N'-diacetyl-
WLN: 1VM2SS2MV1
CBDivE_005129
SCHEMBL917149
Acetamide, N,N'-(dithiodi-2,1-ethanediyl)bis- (9CI)
DTXSID10213245
Acetamide,N-(dithiodiethylene)di-
N,N-(Dithiodiethylene)diacetamide
N,N'-(Dithiodiethylene)diacetamide
AAA63844
Acetamide,N'-(dithiodiethylene)bis-
NSC175859
AKOS024356785
NSC-175859
Acetamide,N'-(dithiodi-2,1-ethanediyl)bis-
NS00035590
2,2'-Dithiobis(ethanamine), N,N'-diacetyl-
EN300-312247
N-(2-([2-(Acetylamino)ethyl]disulfanyl)ethyl)acetamide #