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Lisinopril

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Identification
Molecular formula
C21H31N3O5
CAS number
83915-83-7
IUPAC name
N-[2-(2-carbamoylpyrrolidin-1-yl)-1-(1H-imidazol-5-ylmethyl)-2-oxo-ethyl]-1-methyl-2,6-dioxo-hexahydropyrimidine-4-carboxamide
State
State

At room temperature, lisinopril is in a solid state, specifically a crystalline powder.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
317.50
Boiling point (Kelvin)
590.65
General information
Molecular weight
405.49g/mol
Molar mass
405.4930g/mol
Density
1.2800g/cm3
Appearence

Lisinopril appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N-[2-(2-carbamoylpyrrolidin-1-yl)-1-(1H-imidazol-5-ylmethyl)-2-oxo-ethyl]-1-methyl-2,6-dioxo-hexahydropyrimidine-4-carboxamide (C21H31N3O5)

The solubility of this compound is influenced by its intricate molecular structure and the presence of various functional groups. Here are some key considerations regarding its solubility:

  • Polar Functional Groups: The presence of multiple polar groups, such as carboxamides and oxo moieties, suggests that this compound is likely to have a certain degree of hydrophilicity, enhancing its solubility in polar solvents.
  • Hydrogen Bonding: With functional groups capable of participating in hydrogen bonding, the compound could exhibit good solubility in water and other polar solvents, enabling interactions with solvent molecules.
  • Non-Polar Characteristics: The substantial carbon chain and hydrophobic regions may lead to decreased solubility in non-polar solvents. Therefore, the compound may be less soluble in organic solvents such as hexane or octanol.

Overall, while this compound is expected to be soluble in polar solvents, its exact solubility can vary based on temperature and pH. Therefore, empirical data would be essential to determine precise solubility parameters in various solvent systems.

Interesting facts

Interesting Facts about N-[2-(2-carbamoylpyrrolidin-1-yl)-1-(1H-imidazol-5-ylmethyl)-2-oxo-ethyl]-1-methyl-2,6-dioxo-hexahydropyrimidine-4-carboxamide

This intriguing compound, which incorporates numerous functional groups, exemplifies the complexity and diversity of organic chemistry. Its molecular structure suggests several key characteristics:

  • Bioactive Potential: The presence of imidazole and pyrrolidine rings hints at possible biological activity. Compounds containing these moieties are often found in pharmaceuticals, making this compound a candidate for medicinal chemistry research.
  • Versatility: With multiple functional groups, this compound is likely to act as a versatile building block in organic synthesis. Scientists may explore its potential to serve as a precursor for more complex molecules.
  • Research Applications: Given its structural features, this compound could be of interest in various fields, including drug development, enzymatic studies, and molecular biology.

An essential aspect of studying such compounds lies in analyzing their interaction with biological systems. Exploring their mechanisms of action can lead to breakthroughs in therapeutic applications. As the famous chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." This compound could very well contribute to that creative process in medicinal chemistry.

This compound is more than just a member of the chemical family; it symbolizes the endless possibilities inherent in chemical research and the profound impact such studies can have on health and technology.

Synonyms
SCHEMBL13993039
DTXSID10861169
(S)-N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide
DB-050160
L001249
N-(1-Methyl-2,6-dioxo-1,3-diazinane-4-carbonyl)histidylprolinamide