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Metformin Hydrochloride

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Identification
Molecular formula
C4H11N5 · HCl
CAS number
1115-70-4
IUPAC name
[N'-[2-(2-methylpiperidin-1-ium-1-yl)ethyl]carbamimidoyl]ammonium;sulfate
State
State

At room temperature, Metformin hydrochloride exists as a solid.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
867.00
Boiling point (Kelvin)
1 140.00
General information
Molecular weight
165.63g/mol
Molar mass
165.6300g/mol
Density
1.6500g/cm3
Appearence

Metformin hydrochloride is typically white to off-white in appearance. It presents itself as a crystalline powder.

Comment on solubility

Solubility of [N'-[2-(2-methylpiperidin-1-ium-1-yl)ethyl]carbamimidoyl]ammonium sulfate

The solubility of the compound [N'-[2-(2-methylpiperidin-1-ium-1-yl)ethyl]carbamimidoyl]ammonium sulfate, is influenced by several factors, which can be summarized as follows:

  • Polar Nature: Due to its quaternary ammonium structure, the compound is expected to exhibit good solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of multiple functional groups in the molecule can facilitate hydrogen bonding, further enhancing solubility in aqueous environments.
  • Counterion Influence: The sulfate ion is known to be highly soluble in water and typically promotes the overall solubility of the associated ammonium salt.
  • Temperature Dependence: Solubility may also vary with temperature; generally, an increase in temperature can lead to an increase in solubility for many ionic compounds.

In conclusion, while the specific solubility value might require empirical measurement, we can predict that this compound is likely to be highly soluble in polar solvents, particularly water, due to its ionic nature and the influence of its sulfate component. As with many such compounds, further studies may reveal more nuanced behavior under various conditions.

Interesting facts

Interesting Facts About N'-[2-(2-methylpiperidin-1-ium-1-yl)ethyl]carbamimidoyl]ammonium; sulfate

This intriguing compound presents a unique structure that piques the interest of both chemical scientists and students alike. The presence of the piperidinium group marks it as a compound with potential implications in medicinal chemistry, particularly in the design of pharmaceuticals. Here are some noteworthy facts about this compound:

  • Structural Dynamics: The compound features a complex arrangement, integrating a piperidinium moiety, which is known for its ability to modulate biological activity due to its nitrogen atom's positive charge.
  • Applications in Research: Researchers are exploring the potential of similar compounds in various fields such as neuropharmacology and materials science, taking advantage of the unique properties of piperidines and ammonium ions.
  • Inhibition Mechanisms: Compounds like this one can act as enzyme inhibitors, and the carbamimidoyl group may contribute to the compound's ability to interact with biological targets, making it a candidate for further investigation in drug design.
  • Hydrogen Bonding: The ammonium part of this structure is anticipated to engage in significant hydrogen bonding, which may enhance the solubility profile and reactivity of the compound within biological systems.
  • Ion Pair Considerations: As a sulfate salt, this compound may exhibit distinct physical properties compared to its free base, influencing its behavior in solution and potential use in formulations.

This compound embodies the fascinating intersection of organic chemistry and pharmacology, and studying its properties can yield insights into the development of novel therapeutic agents. As the field of medicinal chemistry progresses, compounds like N'-[2-(2-methylpiperidin-1-ium-1-yl)ethyl]carbamimidoyl] ammonium; sulfate are likely to play a pivotal role in future innovations.