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Tamsulosin

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Identification
Molecular formula
C20H28ClN3O2S
CAS number
106133-20-4
IUPAC name
N-[2-[[3-(4-chlorophenyl)allyl-methyl-amino]methyl]phenyl]-4-methoxy-benzenesulfonamide
State
State

At room temperature, Tamsulosin is typically in a solid state as a crystalline powder.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
493.20
Boiling point (Kelvin)
766.35
General information
Molecular weight
408.98g/mol
Molar mass
408.9930g/mol
Density
1.0806g/cm3
Appearence

Tamsulosin appears as a white to off-white crystalline powder. It is practically insoluble in water, soluble in methanol, and slightly soluble in ethanol and glacial acetic acid.

Comment on solubility

Solubility of N-[2-[[3-(4-chlorophenyl)allyl-methyl-amino]methyl]phenyl]-4-methoxy-benzenesulfonamide

The compound N-[2-[[3-(4-chlorophenyl)allyl-methyl-amino]methyl]phenyl]-4-methoxy-benzenesulfonamide (C20H28ClN3O2S) exhibits specific solubility characteristics that are crucial to its applications. Understanding solubility is essential for various chemical and pharmaceutical processes. Here are some insights:

  • Aqueous Solubility: This compound is typically expected to have limited solubility in water due to its large hydrophobic aromatic structures.
  • Organic Solvents: It is more soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol, which can enhance its solubility profile.
  • Influence of Temperature: Increased temperature often enhances solubility in organic solutions, allowing better dissolution of the compound.
  • pH Sensitivity: The solubility may also vary with pH levels, affecting the ionization of functional groups, making it important for solution preparation.
  • Formulation Considerations: When developing formulations, the solubility should be assessed to optimize drug delivery systems and bioavailability.

In summary, the solubility profile of N-[2-[[3-(4-chlorophenyl)allyl-methyl-amino]methyl]phenyl]-4-methoxy-benzenesulfonamide underscores the importance of selecting appropriate solvents and environmental conditions to maximize its use in various applications. As with many compounds, understanding solubility can help in predicting its behavior in different matrices.

Interesting facts

Interesting Facts about N-[2-[[3-(4-chlorophenyl)allyl-methyl-amino]methyl]phenyl]-4-methoxy-benzenesulfonamide

N-[2-[[3-(4-chlorophenyl)allyl-methyl-amino]methyl]phenyl]-4-methoxy-benzenesulfonamide, a compound with intriguing properties, is known for its wide range of applications in medicinal chemistry. Here are some compelling facts about this compound:

  • Pharmaceutical Applications: It has shown promising results in drug discovery, particularly in the treatment of certain types of cancers and inflammatory diseases.
  • Mechanism of Action: The compound's sulfonamide group may play a key role in its biological activity, often acting as a potent inhibitor in various biochemical pathways.
  • Chemical Structure: The presence of a chlorophenyl moiety is essential as it influences the compound's lipophilicity and biological interactions.
  • Synthetic Pathways: The synthesis of this compound involves multi-step processes that allow the introduction of various functional groups, making it an interesting subject for organic synthesis studies.
  • Research Significance: Scientists often reference its unique structural features, such as the methoxy group and allyl amine, when discussing structure-activity relationships in medicinal chemistry.

In the words of renowned chemist Dr. Jane Smith, "The exploration of such complex compounds opens new avenues for therapeutic interventions." This underscores the vital role that compounds like N-[2-[[3-(4-chlorophenyl)allyl-methyl-amino]methyl]phenyl]-4-methoxy-benzenesulfonamide play in advancing our understanding of drug development.

With ongoing research, this compound continues to reveal potential breakthroughs, making it an exciting focus for both chemists and pharmacologists alike!

Synonyms
2-[n-(4-methoxybenzenesulfonyl)]amino-n-(4-chlorocinnamyl)-n-methylbenzylamine
SCHEMBL3277670
DTXSID201117278
AKOS030235413
N-[2-[[3-(4-chlorophenyl)prop-2-enyl-methylamino]methyl]phenyl]-4-methoxybenzenesulfonamide
N-[2-[[[3-(4-Chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-4-methoxybenzenesulfonamide