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Melatonin

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Identification
Molecular formula
C13H16N2O2S
CAS number
73-31-4
IUPAC name
N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide
State
State

At room temperature, melatonin is a solid. It exists in a stable form as a crystalline powder and does not exhibit a liquid or gaseous state unless it is heated above its melting point.

Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
552.30
Boiling point (Kelvin)
825.45
General information
Molecular weight
232.35g/mol
Molar mass
232.3170g/mol
Density
1.1740g/cm3
Appearence

Melatonin appears as a white to off-white crystalline powder. It is generally characterized by its solid form and its crystalline nature under normal conditions. The purity can affect the exact shade and crystalline form, but it is typically uniform in its appearance when observed in a pure state.

Comment on solubility

Solubility of N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide

N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide is a compound of interest due to its potential biological activity.

In terms of solubility, it exhibits several key characteristics:

  • Polarity: The presence of the acetamide group contributes to a degree of polarity, which can influence its interaction with solvents.
  • Solvents: This compound may be soluble in polar organic solvents such as:
    1. Dimethyl sulfoxide (DMSO)
    2. Ethanol
    3. Water, to a lesser extent, due to its hydrophobic components
  • Hydrophobic Considerations: The methoxybenzothiophene moiety is largely hydrophobic, possibly hindering solubility in purely aqueous environments.
  • pH Impact: Changes in pH can alter the solubility profile, particularly if the compound can ionize under certain conditions.

In summary, while N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide may show reasonable solubility in certain organic solvents, its overall solubility is mediated by its structural components and environmental conditions. Understanding these solubility characteristics is crucial for applications in medicinal chemistry and material science.


Interesting facts

Interesting Facts about N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide

N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide is a compound that belongs to a fascinating class of molecules with intriguing characteristics. Here are some compelling insights about this chemical:

  • Molecular Structure: This compound features a benzothiophene backbone, which is a fused bicyclic structure containing a sulfur atom. This unique arrangement contributes to the compound's distinct chemical reactivity and biological properties.
  • Biological Significance: Compounds like N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide are often studied for their potential therapeutic effects. They may exhibit significant biological activity, making them valuable in drug discovery and development.
  • Research Potential: The presence of the methoxy group can influence the compound's lipophilicity and selectivity in biological systems. Researchers are particularly interested in how such modifications can enhance the efficacy of medicinal compounds.
  • Applications: Due to its structure, this compound may have applications that span various fields, including pharmacology, material science, and organic synthesis.
  • Future Directions: Continued research into compounds like N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide could pave the way for developing new therapies that target specific biological pathways, especially in diseases where traditional treatments have limitations.

This compound exemplifies how modifications at a molecular level can create substances with diverse and potentially beneficial applications. As scientists continue to explore its properties, N-[2-(5-methoxybenzothiophen-3-yl)ethyl]acetamide may hold the key to unlocking new scientific discoveries.

Synonyms
ACETAMIDE, N-(2-(5-METHOXYBENZO(b)THIEN-3-YL)ETHYL)-
28462-87-5
DTXSID10182664
RefChem:1075324
DTXCID50105155
CHEMBL109235
BRN 1379764
N-(2-(5-Methoxybenzo(b)thien-3-yl)ethyl)acetamide
SCHEMBL7024784
BDBM50037219
N-[2-(5-Methoxy-benzo[b]thiophen-3-yl)-ethyl]-acetamide