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Acetanilide

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Identification
Molecular formula
C10H11NO
CAS number
103-84-4
IUPAC name
N-(2-acetylphenyl)acetamide
State
State

Acetanilide is in a solid state at room temperature. It is often encountered in powdered or crystalline form, underscoring its stability and ease of handling under standard conditions.

Melting point (Celsius)
114.30
Melting point (Kelvin)
387.45
Boiling point (Celsius)
304.00
Boiling point (Kelvin)
577.15
General information
Molecular weight
135.16g/mol
Molar mass
135.1630g/mol
Density
1.2190g/cm3
Appearence

Acetanilide is a white crystalline solid with a distinctive odor. It possesses a shimmering appearance and is typically found as a fine powder or crystalline flakes.

Comment on solubility

Solubility of N-(2-acetylphenyl)acetamide

N-(2-acetylphenyl)acetamide, with the chemical formula C10H11NO2, exhibits intriguing solubility characteristics that are important for its applications in various chemical processes.

When discussing its solubility, it's essential to consider:

  • Solvent Interaction: N-(2-acetylphenyl)acetamide is generally soluble in polar solvents, such as water, due to the presence of functional groups capable of hydrogen bonding.
  • Organic Solvents: This compound also shows solubility in common organic solvents like ethanol and acetone, which facilitate its use in organic synthesis.
  • Temperature Dependency: The solubility may increase with temperature; hence, higher temperatures can enhance the dissolution process.

Overall, the solubility of N-(2-acetylphenyl)acetamide is a crucial factor for its usability in pharmaceuticals and chemical formulations. It is often said that "the more soluble a compound, the more versatile it becomes in chemical applications."

Researchers should always consider the solubility profile of this compound to ensure optimal conditions for synthesis and application. With its effective solvation characteristics, N-(2-acetylphenyl)acetamide remains an interesting subject for further studies in solubility behavior.

Interesting facts

Interesting Facts about N-(2-acetylphenyl)acetamide

N-(2-acetylphenyl)acetamide, often referred to in research and industrial chemistry settings, is a fascinating compound that showcases the intricate interplay between organic chemistry and biological activity. Here are some noteworthy aspects:

  • Organic Synthesis: This compound serves as a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its structure allows for numerous chemical modifications, making it versatile in synthesizing complex molecules.
  • Biological Properties: N-(2-acetylphenyl)acetamide is of interest for its potential biological activities. Research has indicated that it may possess anti-inflammatory and analgesic properties, making it a candidate for further studies in drug development.
  • Research Applications: In the realm of research, compounds like N-(2-acetylphenyl)acetamide are often utilized to explore reaction mechanisms and to test the efficacy of new synthetic pathways. They provide insights into reaction conditions and catalysts.
  • Importance in Medicinal Chemistry: The functional groups present in N-(2-acetylphenyl)acetamide allow for interactions with biological targets, enhancing our understanding of structure-activity relationships (SAR) in drug design.
  • Market Significance: Given its potential applications, this compound is of interest not only in academic research but also in the industrial sector, particularly in the production of specialty chemicals and fine pharmaceuticals.

As scientists continue to explore the properties and applications of N-(2-acetylphenyl)acetamide, it becomes increasingly clear that compounds like this one pave the way for innovations in medicine and chemical synthesis. Their role in connecting diverse fields of study underscores the beauty of chemistry as a discipline.

Synonyms
N-(2-Acetylphenyl)acetamide
5234-26-4
N-(2-acetyl-phenyl)-acetamide
2'-Acetamidoacetophenone
o-Acetamidoacetophenone
2'-Acetylacetanilide
Acetamide, N-(2-acetylphenyl)-
ACETANILIDE, 2'-ACETYL-
2'-(Acetylamino)acetophenone
2-ACETAMIDOACETOPHENONE
F1K8P8A71N
NSC-12469
ACETOPHENONE, O-ACETYLAMINO
Acetamido-2 acetophenone [French]
Acetamido-2 acetophenone
NSC 12469
BRN 0908950
NSC12469
MFCD00032277
UNII-F1K8P8A71N
4-14-00-00092 (Beilstein Handbook Reference)
SCHEMBL505353
N-(2-Acetylphenyl)-acetamide
DTXSID80200369
1-[2-(acetylamino)phenyl]ethanone
N-(O-ACETYLPHENYL)ACETAMIDE
AKOS000190275
2'-(N-ACETYLAMINO)ACETOPHENONE
AB19004
BS-28554
N-[2-(1-oxo-1-ethanyl)phenyl]acetamide
DB-071516
N-[2-(1-oxo-1-ethanyl)-phenyl]acetamide
CS-0453237
N-(2-Acetylphenyl)-acetamide;2'-Acetylacetanilide
Z27879706