Skip to main content

Trimetazidine

ADVERTISEMENT
Identification
Molecular formula
C14H22N2O3
CAS number
5011-34-7
IUPAC name
N-[(2-amino-6-methyl-3-pyridyl)methyl]-3,4,5-trimethoxy-benzamide
State
State

At room temperature, trimetazidine is in a solid state, typically a crystalline powder. It is commonly encountered in a pharmaceutical context as a component in tablet formulations.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.15
Boiling point (Celsius)
618.00
Boiling point (Kelvin)
891.15
General information
Molecular weight
266.34g/mol
Molar mass
0.0000g/mol
Density
1.2112g/cm3
Appearence

Trimetazidine is usually available in the form of white to off-white crystalline powder. The substance is odorless, and its appearance can also be described as solid at room temperature.

Comment on solubility

Solubility of N-[(2-amino-6-methyl-3-pyridyl)methyl]-3,4,5-trimethoxy-benzamide

The solubility of N-[(2-amino-6-methyl-3-pyridyl)methyl]-3,4,5-trimethoxy-benzamide can be quite complex due to its multi-functional structure. The presence of the pyridine moiety and various methoxy groups contributes to its unique solubility characteristics. Here are some key points to consider:

  • Solvent Dependence: This compound is generally expected to exhibit variable solubility in different organic solvents. It may show a higher solubility in polar solvents compared to non-polar ones.
  • Hydrogen Bonding: The amino group may facilitate hydrogen bonding interactions with solvents, enhancing solubility in polar environments.
  • Temperature Impact: As with many organic compounds, increasing the temperature could lead to increased solubility, particularly in organic solvents.
  • pH Influence: Alteration of the pH can also influence solubility due to potential protonation of the amino group, affecting the compound's behavior in aqueous environments.

In summary, the solubility of N-[(2-amino-6-methyl-3-pyridyl)methyl]-3,4,5-trimethoxy-benzamide is influenced by several factors including solvent type, temperature, and pH. Understanding these parameters is crucial for practical applications.

Interesting facts

Interesting Facts about N-[(2-amino-6-methyl-3-pyridyl)methyl]-3,4,5-trimethoxy-benzamide

N-[(2-amino-6-methyl-3-pyridyl)methyl]-3,4,5-trimethoxy-benzamide is an intriguing chemical compound with several noteworthy characteristics, making it a subject of interest for both researchers and students in the pharmaceutical and chemical sciences. Here are some key facts:

  • Pharmacological Relevance: This compound is often studied for its potential as a therapeutic agent. The presence of the benzamide structure linked to a pyridyl ring suggests that it may interact with various biological targets.
  • Structure-Activity Relationship: The unique combination of methoxy groups on the benzene ring and the amine substitution on the pyridine provides a rich field for understanding how structural variations influence biological activity.
  • Research Applications: Studies involving this compound may explore its role in receptor binding, enzyme inhibition, or as a potential lead compound for drug development, especially in the context of neurological disorders.
  • Academic Interest: Chemistry students often investigate this compound through practical laboratory work, focusing on synthesis and characterization methods, which enhances their understanding of organic synthesis principles.
  • Chemical Behavior: The presence of different functional groups in this molecule contributes to its reactivity and can lead to various derivatives, broadening its scope in chemical studies.

As noted by researchers, "Compounds like N-[(2-amino-6-methyl-3-pyridyl)methyl]-3,4,5-trimethoxy-benzamide highlight the intricate relationships between molecular structure and function. A thorough understanding can pave the way for novel therapeutic strategies." This highlights the importance of continuing research in this area.

In conclusion, this compound adds to the diverse landscape of organic compounds, attracting interest for its application in medicinal chemistry, synthetic methodology, and the exploration of chemical properties.

Synonyms
Trimetamide
TRIMETHAMIDE
5789-72-0
Trimetamida
Trimetamide [INN]
Trimetamidum
UNII-839184U8NM
839184U8NM
TRIMETAMIDE [WHO-DD]
DTXSID9075036
N-((2-Amino-6-methyl-3-pyridyl)methyl)-3,4,5-trimethoxybenzamide
Benzamide, N-((2-amino-6-methyl-3-pyridinyl)methyl)-3,4,5-trimethoxy-
Benzamide, N-((2-amino-6-methyl-3-pyridyl)methyl)-3,4,5-trimethoxy-
DTXCID7042277
N-[(2-amino-6-methylpyridin-3-yl)methyl]-3,4,5-trimethoxybenzamide
SCHEMBL6767972
CHEMBL2106481
NS00124780
Q27269415
N-(2-amino-6-methyl-3-pyri-dylmethyl)-3,4,5-trimethoxy-benzamid