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N-(2-aminoethyl)-4-chloro-benzamide

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Identification
Molecular formula
C9H11ClN2O
CAS number
121-56-8
IUPAC name
N-(2-aminoethyl)-4-chloro-benzamide
State
State

At room temperature, N-(2-aminoethyl)-4-chloro-benzamide is typically found as a solid.

Melting point (Celsius)
124.00
Melting point (Kelvin)
397.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
200.65g/mol
Molar mass
200.6520g/mol
Density
1.2960g/cm3
Appearence

N-(2-aminoethyl)-4-chloro-benzamide typically appears as an off-white to light yellow crystalline solid. The color and texture can vary depending on the purity and the specific conditions of the sample.

Comment on solubility

Solubility of N-(2-aminoethyl)-4-chloro-benzamide

N-(2-aminoethyl)-4-chloro-benzamide, with the chemical formula C9H11ClN2O, exhibits interesting solubility characteristics that can be influenced by its molecular structure. Here are some key points regarding its solubility:

  • Polarity: The presence of the amino group and the carbonyl (amide) group in the molecule contributes to a degree of polarity, which often enhances solubility in polar solvents.
  • Solvent Compatibility: This compound is likely to be soluble in water and other polar solvents due to its ability to form hydrogen bonds. However, its solubility in organic solvents can vary significantly.
  • Concentration Dependency: The solubility may increase with temperature, or it may demonstrate concentration-dependent behavior, which is crucial for applications in synthesis and formulation.
  • Performance in Different pH Conditions: As the amine can accept protons, varying the pH can significantly affect its solubility. In acidic conditions, the molecule may become more soluble as it forms a positively charged species.

Overall, understanding the solubility of N-(2-aminoethyl)-4-chloro-benzamide is essential for its practical applications, including its use in biochemical studies, pharmaceuticals, and material sciences. The interplay of its functional groups and the surrounding environment uniquely dictate its solubility behavior.

Interesting facts

Interesting Facts about N-(2-Aminoethyl)-4-chloro-benzamide

N-(2-aminoethyl)-4-chloro-benzamide is a fascinating compound that finds its applications in the fields of medicinal chemistry and organic synthesis. Here are some intriguing aspects of this compound:

  • Pharmaceutical Relevance: This compound is often studied for its potential role in drug development, particularly as a scaffold for creating various pharmaceutical agents.
  • Biological Activity: N-(2-aminoethyl)-4-chloro-benzamide may exhibit significant interaction with biological targets, making it a candidate for further investigation in the realm of biological sciences.
  • Synthesis Challenge: Its synthesis can be quite challenging, often requiring careful consideration of reaction conditions and reagent selection, providing a valuable learning experience for budding chemists.
  • Applications in Research: This compound is often utilized in research to explore the structure-activity relationships of similar chemical entities, broadening the understanding of how different functional groups affect the properties of compounds.
  • Multi-Functional Potential: Due to the presence of both amine and amide functional groups, N-(2-aminoethyl)-4-chloro-benzamide can serve as a versatile intermediate in organic transformations.

The study of compounds like N-(2-aminoethyl)-4-chloro-benzamide not only enhances our understanding of chemistry but also paves the way for future innovations in pharmaceuticals and materials science. As a quote by renowned chemist Robert H. Grubbs states, "Chemistry is the science of matter, but I prefer to see it as the science of change." In this case, the study of such compounds exemplifies the transformative nature of chemical research.

Synonyms
N-(2-aminoethyl)-4-chlorobenzamide
87235-61-8
CHEMBL338404
Ro 16-6491
Ro-166491
Benzamide, N-(2-aminoethyl)-4-chloro-
Ro 16-6941
Ro-16-6491
Spectrum_000099
Tocris-0376
Lopac-R-106
Spectrum2_001968
Spectrum3_001603
Spectrum4_000880
Spectrum5_001211
Lopac0_001103
BSPBio_003205
KBioGR_001579
KBioSS_000519
DivK1c_000673
SPBio_002095
SCHEMBL3506361
CHEBI:92783
KBio1_000673
KBio2_000519
KBio2_003087
KBio2_005655
KBio3_002425
RO 16-6491 (free base)
AIHKMGLJGLKLSI-UHFFFAOYSA-N
NINDS_000673
DTXSID101007432
BBL018643
BDBM50063994
STL194214
N-(2-aminoethyl)-4-chloro-benzamide
AKOS000147526
CCG-205179
IDI1_000673
UPCMLD0ENAT5970959:001
NCGC00015879-01
NCGC00015879-02
NCGC00015879-03
NCGC00024560-01
NCGC00024560-02
VS-06721
DB-230893
CS-0268166
EN300-57536
F21193
BRD-K44899736-003-02-1
Q27164544
N- (2-AMINOETHYL)-4-CHLOROBENZAMIDE (RO-16-6491)