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Brompheniramine

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Identification
Molecular formula
C16H19BrN2O
CAS number
86-22-6
IUPAC name
N'-(2-bromo-4,5-dimethoxy-phenyl)-N'-[2-(diethylamino)ethyl]-N,N-diethyl-ethane-1,2-diamine
State
State

At room temperature, Brompheniramine is in solid state. It is typically found in crystalline form, which is stable under normal conditions and suitable for compounding into tablets or capsules for pharmaceutical use.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.15
Boiling point (Celsius)
456.50
Boiling point (Kelvin)
729.70
General information
Molecular weight
435.34g/mol
Molar mass
435.3410g/mol
Density
1.1920g/cm3
Appearence

Brompheniramine typically appears as a white to off-white crystalline powder. It is slightly soluble in water and freely soluble in alcohol, acetone, and chloroform, reflecting its commonly observed physical state for laboratory use and pharmaceutical preparations.

Comment on solubility

Solubility Overview

The compound N'-(2-bromo-4,5-dimethoxy-phenyl)-N'-[2-(diethylamino)ethyl]-N,N-diethyl-ethane-1,2-diamine exhibits unique solubility characteristics that can be influenced by various factors.

Solubility Characteristics

  • Polar vs. Nonpolar: Its structure contains both polar and nonpolar regions, suggesting that it may be miscible in both polar solvents (like water) and nonpolar solvents (such as organic solvents).
  • Presence of Functional Groups: The presence of multiple alkyl chains and ether functionalities suggests enhanced solubility in organic solvents, while the amine groups could facilitate better interaction with polar solvents.
  • Temperature Dependence: The solubility may increase with temperature, which is common for many organic compounds.
  • pH Dependence: Changes in pH can lead to ionization of the amine groups, enhancing solubility in aqueous solutions.

In summary, the solubility of this compound is likely to be affected by its unique structure and the chemical environment. The balance of polar and nonpolar characteristics, along with environmental factors, plays a crucial role in determining its overall solubility profile.

Interesting facts

Exploring N'-(2-bromo-4,5-dimethoxy-phenyl)-N'-[2-(diethylamino)ethyl]-N,N-diethyl-ethane-1,2-diamine

N'-(2-bromo-4,5-dimethoxy-phenyl)-N'-[2-(diethylamino)ethyl]-N,N-diethyl-ethane-1,2-diamine is a fascinating compound that embodies a rich tapestry of chemical intrigue.

Key Attributes

  • Pharmacological Relevance: This compound is of particular interest in medicinal chemistry, where it may exhibit potential therapeutic effects, specifically in neurological studies.
  • Structural Diversity: The presence of multiple functional groups, including the bromo and methoxy moieties, enhances its reactivity and applicability in organic synthesis.
  • Biological Interaction: The diethylamino group may facilitate interaction with biological receptors, making it a suitable candidate for drug design.

According to researchers in the field, "Compounds with complex substitutions often reveal hidden biochemical properties." This statement rings true for this compound, as its unique structure can significantly affect its biological activity.

Potential Applications

  • Drug Development: Its innovative structure could lend itself to the creation of novel pharmaceuticals.
  • Research Tool: This compound can serve as a probe in various biochemical assays, helping to elucidate molecular mechanisms.

The continuous exploration of compounds like N'-(2-bromo-4,5-dimethoxy-phenyl)-N'-[2-(diethylamino)ethyl]-N,N-diethyl-ethane-1,2-diamine not only advances our understanding of chemical interactions but also pushes the frontiers of drug discovery. The intersection of chemistry and biological sciences leads to exciting possibilities, highlighting the importance of such structurally rich compounds in ongoing research.

Synonyms
RC-12
RC 12
BRN 2820583
3U40NC6I9X
WR 27653
1,2-Dimethoxy-4-(bis-diethylaminoethyl)-amino-5-bromobenzene
UNII-3U40NC6I9X
DTXSID60209173
1,2-Ethanediamine, N-(2-bromo-4,5-dimethoxyphenyl)-N-(2-(diethylamino)ethyl)-N',N'-diethyl-
WR-27653
DIETHYLENETRIAMINE, 4-(2-BROMO-4,5-DIMETHOXYPHENYL)-1,1,7,7-TETRAETHYL-
N-(2-Bromo-4,5-dimethoxyphenyl)-N-(2-(diethylamino)ethyl)-N',N'-diethyl-1,2-ethanediamine
2-BROMO-N,N-BIS(DIETHYLAMINO)-4,5-DIMETHOXYANILINE
1,2-ETHANEDIAMINE, N1-(2-BROMO-4,5-DIMETHOXYPHENYL)-N1-(2-(DIETHYLAMINO)ETHYL)-N2,N2-DIETHYL-
N1-(2-BROMO-4,5-DIMETHOXYPHENYL)-N1-(2-(DIETHYLAMINO)ETHYL)-N2,N2-DIETHYL-1,2-ETHANEDIAMINE
DTXCID80131664
1,2-dimethoxy-4-bis(diethylaminoethyl)amino-5-bromobenzene
6042-36-0
4-(2-Bromo-4,5-dimethoxyphenyl)-1,1,7,7-tetraethyldiethylenetriamine
N-(2-BROMO-4,5-DIMETHOXYPHENYL)-N-(2-DIETHYLAMINOETHYL)-N',N'-DIETHYLETHANE-1,2-DIAMINE