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Brompheniramine

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Identification
Molecular formula
C16H19BrClN
CAS number
86-22-6
IUPAC name
N-[(2-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine
State
State

At room temperature, brompheniramine is in a solid state, usually found in pharmaceutical preparations such as tablets and liquid formulations.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
195.00
Boiling point (Kelvin)
468.15
General information
Molecular weight
319.66g/mol
Molar mass
319.6610g/mol
Density
1.2800g/cm3
Appearence

Brompheniramine maleate typically appears as an off-white to yellowish, crystalline solid. It may be available as a powder or for pharmaceutical use, in forms such as tablets with additional excipients.

Comment on solubility

Solubility of N-[(2-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine

The solubility of N-[(2-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine exhibits certain intriguing characteristics that are worth discussing:

  • Polarity: This compound, with its bromo and chloro substituents, tends to be somewhat polar. This polarity may enhance its solubility in polar solvents.
  • Solvent Compatibility: The following solvent systems are likely to impact its solubility:
    • Highly polar solvents (e.g., water, methanol): Moderate solubility expected due to polar interactions.
    • Non-polar solvents (e.g., hexane, toluene): Limited solubility likely due to the compound's polar character.
  • Temperature Influence: As with many organic compounds, solubility can increase with temperature. For applications where higher solubility is desired, consider adjusting the temperature:
    • Increased kinetic energy helps overcome solvation barriers.
  • Structural Factors: The presence of halogens (bromo and chloro groups) plays a significant role in solubility, influencing both intermolecular forces and the overall hydrophobic character.

In summary, while N-[(2-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine displays certain solubility trends, predicting exact values requires precise experimental data. Its unique structure creates a fascinating interplay between polar and non-polar characteristics that can affect its solubility in various environments.

Interesting facts

Interesting Facts about N-[(2-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine

The compound N-[(2-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine is a fascinating example of how modifications to organic compounds can lead to significant changes in their chemical behavior and potential applications. Below are some intriguing aspects of this compound:

  • Structural Complexity: This compound contains a unique structure featuring both bromine and chlorine atoms, which can influence its chemical reactivity and interaction with biological systems.
  • Pharmacological Potential: Due to its amine functional groups, this compound may exhibit pharmacological properties, making it a candidate for further study in medicinal chemistry.
  • Reactivity: The presence of halogens, such as bromine and chlorine, often enhances the reactivity of organic molecules, providing potential pathways for various chemical reactions.
  • Application in Synthesis: Compounds with similar structures are often utilized as intermediates in the synthesis of more complex molecules, especially in the pharmaceutical industry.
  • Environmental Considerations: The halogenated nature of this compound may pose environmental concerns, particularly regarding bioaccumulation and toxicity, prompting further investigation into its environmental fate.

In summary, N-[(2-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine serves as an excellent example of how organic chemistry can lead to compounds with diverse applications, while also highlighting the importance of understanding their environmental impact. As chemists explore such compounds, they unlock potential innovations in drug development and materials science.

Synonyms
N,N-Bis(2-chloroethyl)-o-bromobenzylamine
2361-57-1
N-[(2-bromophenyl)methyl]-2-chloro-N-(2-chloroethyl)ethanamine
2-Bromo-N,N-bis(2-chloroethyl)benzenemethanamine
o-Bromo-dcba
BRN 2838712
o-Bromo-di-(2-chloroethyl)-benzylamine
Benzenemethanamine, 2-bromo-N,N-bis(2-chloroethyl)-
BENZYLAMINE, N,N-BIS(2-CHLOROETHYL)-o-BROMO-
DTXSID00178273
Benzenemethanamine, 2-bromo-N,N-bis(2-chloroethyl)- (9CI)
A1-06038